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Talk:Etazene
Revision as of 12:23, 13 January 2021 by >Stung1130(new article)
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WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.
DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Very little is known about etaznenes origin, it first came to the public eye in 2020, when it was first siezed by law enforcement. People speculate it is a etazene like Research chemical, with similar effects but a much lower LD50
etazene is an analgesic drug, first reported in 2020, that has been shown to have approximately one thousand to one thousand five hundred times the potency of morphine in animal models, but only sixty to seventy times the potency in humans.
Because it is characterized by a strong dependency potential and a tendency to produce profound respiratory depression, it is not used in humans. It is, however, useful in animal models for addiction studies, particularly those requiring the animals to drink or ingest the agent, because it is not as bitter as opiate salts like morphine sulfate.
Pharmacology
etazene is a synthetic opioid in the phenylpiperidine family, which includes sufentanil, alfentanil, remifentanil, and carfentanil
The structures of opioids share many similarities. Whereas opioids like codeine, hydrocodone, oxycodone, and hydromorphone are synthesized by simple modifications of morphine, etazene and its relatives are synthesized by modifications of meperidine. Meperidine is a fully synthetic opioid, and other members of the phenylpiperidine family like alfentanil and sufentanil are complex versions of this structure. etazene is a weak base that is highly lipid-soluble, protein-bound, and protonated at physiological pH
Subjective effects
subjective effects include:
euphoria
muscle relaxation
sedation
pupil constriction
mood lift
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI),It is worth noting that these effects will not necessarily occur in a consistent or reliable manner, although higher doses are more likely to induce the full spectrum of effects. Likewise, adverse effects become much more likely with higher doses and may include serious injury or death.
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Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
Physical effects
You may select physical effects to add below [[
Sedation - etazene can be described as much more sedating then other opiates. Even at moderate dosages, etazene can result in overwhelming feelings of sedation and tiredness that is considerably more sedating than that of heroin and oxycodone.
Pain relief - In comparison to other opiates, etazene can be described as a strong analgesic, providing relief even at non-recreational doses.
Physical euphoria - etazene can be considered as less intense in its physical euphoria when compared with that of morphine or diacetylmorphine (heroin). The sensation itself can be described as strong feelings of intense physical comfort, warmth and bliss which spread throughout the body.
Itchiness - Unlike other opioids, etazene presents very little itch response due to little to no amounts of released histamines.
Respiratory depression - In comparison to other opiates, etazene displays this effect at lower doses relative to euphoria then other opiates, and even at low doses results in the sensation that the breath is slowed down mildly to moderately, but does not cause noticeable impairment. At high doses and overdoses, opioid-induced respiratory depression can result in a shortness of breath, abnormal breathing patterns, semi-consciousness, or unconsciousness. Severe overdoses can result in a coma or death without immediate medical attention.
Constipation
Cough suppression
Decreased libido
Difficulty urinating
Pupil constriction
Increased perspiration
Decreased blood pressure
Appetite suppression
Orgasm suppression
]].
Cognitive effects
etazene may produce cognitive impairment and decrease your reflexes significantly, depending on the dose. it might induce slurred speech.
You may select from a list of transpersonal effects to add below here.
Experience reports
There are currently 0 experience reports which describe the effects of this substance in our experience index.
This toxicity and harm potential section is a stub.
As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it. Note: Always conduct independent research and use harm reduction practices if using this substance.
Tolerance to ethazene builds up rather quickly and can be compared to the tolerance build up of fentanyl and other analogues. it is unclear how addictive it is but most anecdotal reports find it very easy to abuse, mainly due to the compulsive redosing disorder wich often occurs under the influence