List of polysubstance combinations
Poly drug use refers to the use of two or more psychoactive drugs in combination to achieve a particular effect. In many cases one drug is used as a base or primary drug, with additional drugs to leaven or compensate for the side effects of the primary drug and make the experience more enjoyable with drug synergy effects, or to supplement for primary drug when supply is low.

Notable combinations
- Cocaine
- DMT
- Pharmahuasca: DMT with MAOIs
- Ayahuasca: DMT with MAOIs
- MDMA
- Candyflip: MDMA with LSD[2]
- Elephant flipping: MDMA with PCP[3]
- Hippy flipping: MDMA with magic mushroom[4]
- Jedi flipping: MDMA with magic mushroom and LSD[5]
- Kitty flipping: MDMA with ketamine[6]
- Love flipping: MDMA with mescaline[7]
- Nexus flip: MDMA with 2C-B[8]
- Robo flipping: MDMA and DXM[9]
- Sextasy: MDMA with sildenafil (Viagra)[10]
- Time flipping: MDMA with DMT
- Purple drank: Codeine with promethazine
References
- ↑ https://www.urbandictionary.com/define.php?term=cocoa+puffs
- ↑ https://www.urbandictionary.com/define.php?term=candy%20flip
- ↑ https://www.urbandictionary.com/define.php?term=Elephant%20Flipping
- ↑ http://www.urbandictionary.com/define.php?term=hippy%20flipping
- ↑ https://www.urbandictionary.com/define.php?term=jedi+flipping
- ↑ https://www.urbandictionary.com/define.php?term=kitty+flipping
- ↑ https://www.urbandictionary.com/define.php?term=love%20flip
- ↑ https://www.urbandictionary.com/define.php?term=Nexus%20flip
- ↑ https://www.urbandictionary.com/define.php?term=Robo+Flipping
- ↑ https://www.urbandictionary.com/define.php?term=sextacy