LAE-32
Lysergic acid ethylamide (also known as LAE-32, LAE, and d-ethyllysergamide) is a semisynthetic psychedelic substance of the lysergamide class that is structurally similar to LSD. LAE-32 is one of the least known and least researched psychedelic substances. The pharmacology of LAE-32 is complex[citation needed], but it acts primarily by binding to serotonin receptors in the brain, much like LSD and other serotonergic psychedelics.[citation needed]
LAE-32 | |||||||||||||
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Chemical Nomenclature | |||||||||||||
Common names | LAE-32, LAE | ||||||||||||
Substitutive name | d-Lysergic acid ethylamide | ||||||||||||
Systematic name | N-ethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide | ||||||||||||
Class Membership | |||||||||||||
Psychoactive class | Psychedelic | ||||||||||||
Chemical class | Lysergamide | ||||||||||||
Routes of Administration | |||||||||||||
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Interactions | |||||||||||||
Cannabis | |||||||||||||
Amphetamines | |||||||||||||
Cocaine | |||||||||||||
Tramadol | |||||||||||||
Summary sheet: LAE-32 |
The CIA and Project MKULTRA Findings
LAE-32 was experimented with by the CIA as part of Project MKULTRA. It was reported to create a condition similar to that of schizophrenia in mentally healthy individuals, characterized by indifference and depersonalization. While it was reported that, when used on schizophrenics, it created a condition that allowed the patients to become indifferent to their hallucinations and cease hallucinatory excitation.