List of polysubstance combinations

Poly drug use refers to the use of two or more psychoactive drugs in combination to achieve a particular effect. In many cases one drug is used as a base or primary drug, with additional drugs to leaven or compensate for the side effects of the primary drug and make the experience more enjoyable with drug synergy effects, or to supplement for primary drug when supply is low.

Notable combinations

DMT
- Pharmahuasca: DMT with MAOIs
- Ayahuasca: DMT with MAOIs
MDMA
- Candyflip: MDMA with LSD^[1]
- Elephant flipping: MDMA with PCP^[2]
- Love flipping: MDMA with mescaline^[3]
- Sextasy: MDMA with sildenafil (Viagra)^[4]
- Hippy flipping: MDMA with magic mushroom^[5]
Purple drank: Codeine with promethazine
Speedball: Cocaine with heroin or morphine
- Cocoa puffs: Cocaine with cannabis.^[6]

References

[1] ttps://www.urbandictionary.com/define.php?term=candy%20flip

[2] ttps://www.urbandictionary.com/define.php?term=Elephant%20Flipping

[3] ttps://www.urbandictionary.com/define.php?term=love%20flip

[4] ttps://www.urbandictionary.com/define.php?term=sextacy

[5] ttp://www.urbandictionary.com/define.php?term=hippy%20flipping

[6] ttps://www.urbandictionary.com/define.php?term=cocoa+puffs

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