Ibotenic acid

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Ibotenic acid or (S)-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid (also referred to as ibotenate) is a psychoactive substance which occurs naturally in Amanita muscaria and related species of mushrooms. It is an analogue of the neurotransmitter glutamate, and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist.

Ibotenic acid can be a powerful neurotoxin, and is employed as a "brain-lesioning agent" through cranial injections in scientific research.

Chemistry

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Pharmacology

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Subjective effects

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