Talk:Cinolazepam: Difference between revisions

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'''Cinolazepam''' ('''Gerodorm''') is a a short-acting [[psychoactive]] drug of the [[Chemical class::benzodiazepine]] class which produces hypnotic, anxiolytic, sedative, muscle relaxant, [[anticonvulsant]], and amnesic effects. Due to its strong sedative properties, it is primarily used as an hypnotic.

'''Cinolazepam''' ('''Gerodorm''') is a a short-acting [[psychoactive]] drug of the [[Chemical class::benzodiazepine]] class which produces hypnotic, anxiolytic, sedative, muscle relaxant, [[anticonvulsant]], and amnesic effects.<ref>A clinical and neurophysiological evaluation of clotiazepam, a new thienodiazepine derivative. | http://www.ncbi.nlm.nih.gov/pubmed/2885366</ref> Due to its strong sedative properties, it is primarily used as an hypnotic.<ref>Short-term sleep laboratory studies with cinolazepam in situational insomnia induced by traffic noise. | http://www.ncbi.nlm.nih.gov/pubmed/2889679</ref>

Cinolazepam has an elimination half-life of approximately 9 hours, and is considered to be a short-acting benzodiazepine. It has a fast onset of action, with a peak blood level occurring 0.5 to 2 hours after oral administration.

Cinolazepam has an elimination half-life of approximately 9 hours, and is considered to be a short-acting benzodiazepine. It has a fast onset of action, with a peak blood level occurring 0.5 to 2 hours after oral administration.<ref>Drug bank | http://www.drugbank.ca/drugs/DB01594</ref>`

At heavy doses, Cinolazepam has been anecdotally reported<ref>https://drugs-forum.com/forum/showpost.php?p=1287037&postcount=2</ref> to produce atypical hallucinatory effects, like those of [[Zolpidem]] and [[Zopiclone]], although to a lighter extent.

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Cinolazepam likely has a [[Toxicity::low toxicity]] relative to dose.<ref>Benzodiazepine metabolism: an analytical perspective (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/18855614</ref> However, it is [[Toxicity::potentially [[respiratory depression|lethal]] when mixed with [[depressants]] like [[alcohol]] or [[opioids]]]].

It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.

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-'''Cinolazepam''' ('''Gerodorm''') is a a short-acting [[psychoactive]] drug of the [[Chemical class::benzodiazepine]] class which produces hypnotic, anxiolytic, sedative, muscle relaxant, [[anticonvulsant]], and amnesic effects. Due to its strong sedative properties, it is primarily used as an hypnotic.
+'''Cinolazepam''' ('''Gerodorm''') is a a short-acting [[psychoactive]] drug of the [[Chemical class::benzodiazepine]] class which produces hypnotic, anxiolytic, sedative, muscle relaxant, [[anticonvulsant]], and amnesic effects.<ref>A clinical and neurophysiological evaluation of clotiazepam, a new thienodiazepine derivative. | http://www.ncbi.nlm.nih.gov/pubmed/2885366</ref> Due to its strong sedative properties, it is primarily used as an hypnotic.<ref>Short-term sleep laboratory studies with cinolazepam in situational insomnia induced by traffic noise. | http://www.ncbi.nlm.nih.gov/pubmed/2889679</ref>
-Cinolazepam has an elimination half-life of approximately 9 hours, and is considered to be a short-acting benzodiazepine. It has a fast onset of action, with a peak blood level occurring 0.5 to 2 hours after oral administration.
+Cinolazepam has an elimination half-life of approximately 9 hours, and is considered to be a short-acting benzodiazepine. It has a fast onset of action, with a peak blood level occurring 0.5 to 2 hours after oral administration.<ref>Drug bank | http://www.drugbank.ca/drugs/DB01594</ref>`
 At heavy doses, Cinolazepam has been anecdotally reported<ref>https://drugs-forum.com/forum/showpost.php?p=1287037&postcount=2</ref> to produce atypical hallucinatory effects, like those of [[Zolpidem]] and [[Zopiclone]], although to a lighter extent.
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 {{Main|Research chemicals#Toxicity and harm potential}}
 Cinolazepam likely has a [[Toxicity::low toxicity]] relative to dose.<ref>Benzodiazepine metabolism: an analytical perspective (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/18855614</ref> However, it is [[Toxicity::potentially [[respiratory depression|lethal]] when mixed with [[depressants]] like [[alcohol]] or [[opioids]]]].
 It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.