Reuptake inhibitor: Difference between revisions

Line 1:

A '''reuptake inhibitor''', also known as a transporter blocker, is a drug that inhibits the reuptake of a [[neurotransmitter]] from the synapse into the presynaptic neurone, leading to an increase in the extracellular concentrations of the neurotransmitter and therefore an increase in neurotransmission. Various drugs utilize reuptake inhibition to exert their psychological and physiological effects, including many [[antidepressants]] and [[stimulants]].

Most known reuptake inhibitors affect the monoamine neurotransmitters [[serotonin]], [[noradrenaline]] (and [[adrenaline]]), and [[dopamine]]. However, there are also a number of pharmaceuticals and [[research chemicals]] that act as reuptake inhibitors for other neurotransmitters such as [[glutamate]], [[GABA]], glycine, adenosine, choline (the precursor of [[acetylcholine]]), and the endocannabinoids~~, among others~~.

Most known reuptake inhibitors affect the monoamine neurotransmitters [[serotonin]], [[noradrenaline]] (and [[adrenaline]]), and [[dopamine]]. However, there are also a number of pharmaceuticals and [[research chemicals]] that act as reuptake inhibitors for other neurotransmitters such as [[glutamate]], [[GABA]], glycine, adenosine, choline (the precursor of [[acetylcholine]]), and the endocannabinoids.

==Mechanism of action==

@@ Line 1: / Line 1: @@
 A '''reuptake inhibitor''', also known as a transporter blocker, is a drug that inhibits the reuptake of a [[neurotransmitter]] from the synapse into the presynaptic neurone, leading to an increase in the extracellular concentrations of the neurotransmitter and therefore an increase in neurotransmission. Various drugs utilize reuptake inhibition to exert their psychological and physiological effects, including many [[antidepressants]] and [[stimulants]].
-Most known reuptake inhibitors affect the monoamine neurotransmitters [[serotonin]], [[noradrenaline]] (and [[adrenaline]]), and [[dopamine]]. However, there are also a number of pharmaceuticals and [[research chemicals]] that act as reuptake inhibitors for other neurotransmitters such as [[glutamate]], [[GABA]], glycine, adenosine, choline (the precursor of [[acetylcholine]]), and the endocannabinoids, among others.
+Most known reuptake inhibitors affect the monoamine neurotransmitters [[serotonin]], [[noradrenaline]] (and [[adrenaline]]), and [[dopamine]]. However, there are also a number of pharmaceuticals and [[research chemicals]] that act as reuptake inhibitors for other neurotransmitters such as [[glutamate]], [[GABA]], glycine, adenosine, choline (the precursor of [[acetylcholine]]), and the endocannabinoids.
 ==Mechanism of action==