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Research chemicals: Difference between revisions
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In terms of known risk factors, common issues for research chemicals include the the mislabeling, misidentification, and misrepresentation of products; the adulteration of other compounds; and issues of purity.<ref name="erowid">Experimental & Research Chemicals (Synthetic Drugs, Novel Psychoactive Substances, New Psychoactive Substances, NPS, Replacement Psychoactives) (Erowid) | https://www.erowid.org/psychoactives/research_chems/</ref> Combining research chemicals presents a risk due to the lack of research and understanding of the drugs' pharmacology. For example, if a research chemical has [[MAOI]] effects (like 2C-T-7), this could make it dangerous to combine it with other [[MAOI]]s, [[stimulant]]s and certain substances which release [[serotonin]] or [[dopamine]]. It is recommended to avoid blends or branded products if the active psychoactive compounds are not listed on the labelling.<ref name="tripsit">Research Chemicals (Tripsit) | https://wiki.tripsit.me/wiki/Research_Chemicals</ref> | In terms of known risk factors, common issues for research chemicals include the the mislabeling, misidentification, and misrepresentation of products; the adulteration of other compounds; and issues of purity.<ref name="erowid">Experimental & Research Chemicals (Synthetic Drugs, Novel Psychoactive Substances, New Psychoactive Substances, NPS, Replacement Psychoactives) (Erowid) | https://www.erowid.org/psychoactives/research_chems/</ref> Combining research chemicals presents a risk due to the lack of research and understanding of the drugs' pharmacology. For example, if a research chemical has [[MAOI]] effects (like 2C-T-7), this could make it dangerous to combine it with other [[MAOI]]s, [[stimulant]]s and certain substances which release [[serotonin]] or [[dopamine]]. It is recommended to avoid blends or branded products if the active psychoactive compounds are not listed on the labelling.<ref name="tripsit">Research Chemicals (Tripsit) | https://wiki.tripsit.me/wiki/Research_Chemicals</ref> | ||
Several fatal overdoses have occurred due to [[Bromo-DragonFLY]] accidentally being mislabelled by online vendors as both [[2C-B- | Several fatal overdoses have occurred due to [[Bromo-DragonFLY]] accidentally being mislabelled by online vendors as both [[2C-B-FLY]]<ref name="2cbfly">Information on Reported Deaths Related to 2C-B-FLY Misidentified Substance is Most Likely Bromo-dragonfly by the Erowid Crew v1.6 - Nov 9, 2009 | https://www.erowid.org/chemicals/2cb_fly/2cb_fly_death1.shtml</ref> and [[2C-E]].<ref name="2ce">Bromo-Dragonfly Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/bromo_dragonfly/bromo_dragonfly_death.shtml</ref><ref name="2ce2">Second Victim Dies After Taking Designer Drug In Konawa | http://www.newson6.com/story/14641463/second-victim-dies-after-taking-designer-drug-in-konawa</ref> The former is active in the 200-800ug range and is significantly more potent than 2C-E. Situations like this can be avoided by simply dosing a minuscule amount of a drug (roughly 0.5 milligrams) and waiting for several hours. It is recommended to do this for all new batches of drugs that you do not completely trust. | ||
Anecdotal evidence from people who have tried research chemicals within the community suggest that there do not seem to be any negative health effects attributed to simply trying research chemicals at low to moderate doses by themselves and using them sparingly, but nothing can be completely guaranteed. For example, in one extreme case, the research chemical [[MPPP]] was found in some cases to contain an impurity called [[MPTP]], which caused brain damage that could result in a syndrome identical to full-blown Parkinson's disease from only a single dose.<ref name="faq"></ref> | Anecdotal evidence from people who have tried research chemicals within the community suggest that there do not seem to be any negative health effects attributed to simply trying research chemicals at low to moderate doses by themselves and using them sparingly, but nothing can be completely guaranteed. For example, in one extreme case, the research chemical [[MPPP]] was found in some cases to contain an impurity called [[MPTP]], which caused brain damage that could result in a syndrome identical to full-blown Parkinson's disease from only a single dose.<ref name="faq"></ref> | ||
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*'''[[25C-NBOMe]]'''<ref name="two">25C-NBOMe (2C-C-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2cc_nbome/2cc_nbome_death.shtml</ref> | *'''[[25C-NBOMe]]'''<ref name="two">25C-NBOMe (2C-C-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2cc_nbome/2cc_nbome_death.shtml</ref> | ||
*'''[[5-MeO-DiPT]]'''<ref>Japanese Death Associated with 5-MeO-DIPT by Erowid v1.1 May 4, 2006 | https://www.erowid.org/chemicals/5meo_dipt/5meo_dipt_media1.shtml</ref> | *'''[[5-MeO-DiPT]]'''<ref>Japanese Death Associated with 5-MeO-DIPT by Erowid v1.1 May 4, 2006 | https://www.erowid.org/chemicals/5meo_dipt/5meo_dipt_media1.shtml</ref> | ||
*'''[[Bromo-DragonFLY]]''' - Bromo-DragonFLY, accidentally mislabelled as both [[2C-E]]<ref name="2ce">Bromo-Dragonfly Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/bromo_dragonfly/bromo_dragonfly_death.shtml</ref><ref name="2ce2">Second Victim Dies After Taking Designer Drug In Konawa | http://www.newson6.com/story/14641463/second-victim-dies-after-taking-designer-drug-in-konawa</ref> and [[2C-B- | *'''[[Bromo-DragonFLY]]''' - Bromo-DragonFLY, accidentally mislabelled as both [[2C-E]]<ref name="2ce">Bromo-Dragonfly Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/bromo_dragonfly/bromo_dragonfly_death.shtml</ref><ref name="2ce2">Second Victim Dies After Taking Designer Drug In Konawa | http://www.newson6.com/story/14641463/second-victim-dies-after-taking-designer-drug-in-konawa</ref> and [[2C-B-FLY]]<ref name="2cbfly">Information on Reported Deaths Related to 2C-B-FLY Misidentified Substance is Most Likely Bromo-dragonfly by the Erowid Crew v1.6 - Nov 9, 2009 | https://www.erowid.org/chemicals/2cb_fly/2cb_fly_death1.shtml</ref>, has caused the deaths of three people, possibly due to producing pronounced [[vasoconsctriction]] under some circumstances.<ref>Bromo-Dragonfly Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/bromo_dragonfly/bromo_dragonfly_death.shtml</ref><ref>A fatal poisoning involving Bromo-Dragonfly. | https://www.ncbi.nlm.nih.gov/pubmed/19091499</ref> | ||
====Dissociatives==== | ====Dissociatives==== | ||
*'''[[MXP]]'''<ref>Elliott SP, Brandt SD, Wallach J, Morris H, Kavanagh PV. “First Reported Fatalities Associated with the 'Research Chemical' 2-Methoxydiphenidine”. J Anal Toxicol. 2015 May;39(4):287-293. | https://www.erowid.org/references/refs_view.php?ID=8804</ref> | *'''[[MXP]]'''<ref>Elliott SP, Brandt SD, Wallach J, Morris H, Kavanagh PV. “First Reported Fatalities Associated with the 'Research Chemical' 2-Methoxydiphenidine”. J Anal Toxicol. 2015 May;39(4):287-293. | https://www.erowid.org/references/refs_view.php?ID=8804</ref> | ||