GABA: Difference between revisions
>Tracer m Added F-phenibut in Drugs targeting GABAB |
>Tracer m Grammatics |
||
Line 1: | Line 1: | ||
{{DepressantOD|GABAergics}} | {{DepressantOD|GABAergics}} | ||
[[File:GABA.svg|250px|thumb|right|Skeletal structure of the GABA molecule.]] | [[File:GABA.svg|250px|thumb|right|Skeletal structure of the GABA molecule.]] | ||
'''GABA''', also known as '''gamma-aminobutyric acid''', is the main inhibitory neurotransmitter. Drugs targeting GABA include [[Benzodiazepine|benzodiazepines]], [[barbiturates]], [[alcohol]] and [[GHB]]/[[GBL]]. | '''GABA''', also known as '''gamma-aminobutyric acid''', is the main inhibitory [[neurotransmitter]]. Drugs targeting GABA include [[Benzodiazepine|benzodiazepines]], [[barbiturates]], [[alcohol]] and [[GHB]]/[[GBL]]. | ||
A GABAergic agent is a substance which functions to directly modulate the GABA system, the main inhibitory neurotransmitter, in the body or brain. This can include GABA receptor | A GABAergic agent is a substance which functions to directly modulate the GABA system, the main inhibitory neurotransmitter, in the body or brain. This can include GABA [[receptor]] [[agonist]]s, GABA receptor antagonists, and GABA [[reuptake inhibitor]]s. | ||
Substances that indirectly modulate the GABA system are known as "positive allosteric modulators, | Substances that indirectly modulate the GABA system are known as "positive allosteric modulators", and includes [[barbiturates]] and [[benzodiazepines]] as well as [[alcohol]]. [[Flumazenil]] is an example of a "negative allosteric modulator".{{citation needed}} | ||
==Chemistry== | ==Chemistry== |