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STS-135: Difference between revisions
>Oskykins m Text replacement - "There is some concern over the potential toxicity of fluorinated cannabinoids and their napthalene metabolites, so it is strongly discouraged take this substance for extended periods of time or take it in excessive doses.<ref name="one">Rational Cannabinoid Design - From Intoxicant to Chemical Weapon, Blue-Light | http://www.bluelight.org/vb/threads/762639-Rational-Cannabinoid-Design-From-Intoxicant-to-Chemical-Weapon</ref><ref n... |
>Oskykins m Text replacement - "<ref>Every-Palmer, S. Synthetic cannabinoid use and psychosis: an explorative study. Journal of Drug and Alcohol Dependence 2011.</ref> <ref>http://www.sciencedirect.com/science/article/pii/S0736467910008802</ref> <ref>http://journals.lww.com/pec-online/Abstract/2010/06000/A_Teenager_With_Agitation__Higher_Than_She_Should.16.aspx</ref>" to "<ref>Every-Palmer, S. Synthetic cannabinoid use and psychosis: an explorative study. Journal of Drug and Alcohol Dependence 2011.</ref... |
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The toxicity and long-term health effects of recreational STS-135 use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because STS-135 has very little history of human usage. Anecdotal evidence from people who have tried STS-135 within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). Informal experiments have shown that overdose will cause physical discomfort including heart palpitations, vertigo and sedation at much lower than dangerous doses, usually causing the user to suffer large amounts of [[anxiety]] or to fall asleep. | The toxicity and long-term health effects of recreational STS-135 use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because STS-135 has very little history of human usage. Anecdotal evidence from people who have tried STS-135 within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). Informal experiments have shown that overdose will cause physical discomfort including heart palpitations, vertigo and sedation at much lower than dangerous doses, usually causing the user to suffer large amounts of [[anxiety]] or to fall asleep. | ||
It has often been recommended that those with severe pre-existing mental conditions should not ingest these substances due to the way they strongly increase the current mindstate of the person. Also, like [[THC]], prolonged usage of [[cannabinoids]] including STS-135 may increase one's disposition to mental illness and psychosis <ref>http://bjp.rcpsych.org/content/184/2/110.short</ref>, especially in vulnerable individuals with risk factors for psychotic illnesses (like a past or family history of psychosis).<ref>Every-Palmer, S. Synthetic cannabinoid use and psychosis: an explorative study. Journal of Drug and Alcohol Dependence 2011.</ref> <ref>http://www.sciencedirect.com/science/article/pii/S0736467910008802</ref> <ref>http://journals.lww.com/pec-online/Abstract/2010/06000/A_Teenager_With_Agitation__Higher_Than_She_Should.16.aspx</ref> | It has often been recommended that those with severe pre-existing mental conditions should not ingest these substances due to the way they strongly increase the current mindstate of the person. Also, like [[THC]], prolonged usage of [[cannabinoids]] including STS-135 may increase one's disposition to mental illness and psychosis <ref>http://bjp.rcpsych.org/content/184/2/110.short</ref>, especially in vulnerable individuals with risk factors for psychotic illnesses (like a past or family history of psychosis).<ref>Every-Palmer, S. Synthetic cannabinoid use and psychosis: an explorative study. Journal of Drug and Alcohol Dependence 2011.</ref><ref>http://www.sciencedirect.com/science/article/pii/S0736467910008802</ref><ref>http://journals.lww.com/pec-online/Abstract/2010/06000/A_Teenager_With_Agitation__Higher_Than_She_Should.16.aspx</ref> | ||
As the material is active in the milligram range, it is important to [[Responsible use|remain vigilant when dosing]] as to avoid a negative experience. | As the material is active in the milligram range, it is important to [[Responsible use|remain vigilant when dosing]] as to avoid a negative experience. | ||