25I-NBOMe: Difference between revisions
>Jkadosh15 →Subjective effects: multiple reports of Rhabdomyolysis has been reported due to intoxication with this substance |
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It is worth noting that compounds of the [[25x-NBOMe|NBOMe]] family (any of which could be referred to as "N-Bomb", especially 25I-NBOMe and [[25N-NBOMe]]) should be administered [[sublingual|sublingually]] by placing and holding it into one's mouth and allowing it to absorb over a period of 15-25 minutes. | It is worth noting that compounds of the [[25x-NBOMe|NBOMe]] family (any of which could be referred to as "N-Bomb", especially 25I-NBOMe and [[25N-NBOMe]]) should be administered [[sublingual|sublingually]] by placing and holding it into one's mouth and allowing it to absorb over a period of 15-25 minutes. | ||
Extremely little is known about the pharmacological properties, metabolism, and toxicity of 25I-NBOMe in humans. It had no history of human use before being sold online as a [[designer drug]] in 2010. | Extremely little is known about the pharmacological properties, metabolism, and toxicity of 25I-NBOMe in humans. It had no history of human use before being sold online as a [[designer drug]] in 2010.<ref>Musselman ME, Hampton JP. "[https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.1424 Not for human consumption": a review of emerging designer drugs]. Pharmacotherapy. 2014 Jul;34(7):745-57. doi: 10.1002/phar.1424. Epub 2014 Apr 8.</ref> It has been associated with many deaths and hospitalizations. Anecdotal reports suggest that this substance may be difficult to use safely due to its highly sensitive dose-response and unpredictable effects. | ||
==Chemistry== | ==Chemistry== |