Dextroamphetamine: Difference between revisions

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'''Dextroamphetamine''' (also known as '''Dexamphetamine~~''', '''D-Amphetamine'''~~, ~~'''~~Dex~~'''~~, ~~'''~~Dexies''', ~~or by~~ brand names ~~including '~~''Adderall''', ''~~'Attentin'~~'', ''~~'Dexedrine'~~'') is a [[stimulant~~]] substance~~ and the right-handed [~~[enantiomer~~]~~] of~~ [[~~amphetamine~~]].

'''Dextroamphetamine''' (also known as ''Dexamphetamine, Dex, Dexies'', and sold under brand names like ''[[Adderall]]'', ''[https://www.webmd.com/drugs/2/drug-1636-9080/dextroamphetamine-sulfate-oral/dextroamphetamine-oral/details Dexedrine]'', and ''[https://zenzedi.com/ Zenzedi]'') is a central nervous system stimulant and the right-handed enantiomer of amphetamine. It's more potent than its mirror twin, [https://en.wikipedia.org/wiki/Levoamphetamine levoamphetamine], especially in stimulating dopamine and [[Noradrenaline|norepinephrine]] activity in the brain.

~~Dextroamphetamine is the more potent~~ [[~~enantiomer~~]] ~~of the two~~, ~~but the effects are also slightly different in character. The small difference in affinity affects the mechanism resulting in a more mentally focused~~ [[~~stimulation~~]] ~~rather than physical~~, ~~thus creating a~~ [[~~stimulant~~]] ~~that~~ is ~~more fit~~ as a ~~therapeutic drug rather than a recreational one~~. ~~Therefore~~, ~~the dextrorotatory enantiomer is preferred in treatment of attention deficit hyperactivity disorder~~, ~~whereas~~ a [[~~racemic~~]] ~~mixture like~~ [[~~amphetamine~~]] is ~~found when sold on the streets~~.

[[Subjective effects]] include [[stimulation]], increased focus, [[Motivation enhancement|motivation enhancement]], [[Appetite suppression|appetite suppression]], [[wakefulness]], [[Thought acceleration|thought acceleration]], and [[euphoria]]. At lower to moderate doses, it can promote productivity, alertness, and sociability. However, higher doses may induce restlessness, anxiety, compulsive redosing, and over-stimulation. It is classified as a classical stimulant due to its ability to promote mental and physical arousal through increased catecholamine activity.

A notable property of dextroamphetamine is its high potential for abuse and rapid tolerance buildup. Repeated use over short periods can lead to diminished effects, compulsive use patterns, and a pronounced comedown characterized by [https://en.wikipedia.org/wiki/Fatigue#Mental mental fatigue], [[irritability]], and [[anhedonia]].

Recreational or street amphetamine is usually a racemic mix of both enantiomers, resulting in a broader and less focused effect profile compared to pure dextroamphetamine.

It is highly advised to use [[Harm reduction practices|harm reduction practices]] if using this substance.

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==See also==

*[[Responsible use]]

*[[Stimulant]]

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==External links==

*[[wikipedia:Dextroamphetamine|Dextroamphetamine (Wikipedia)]]

*[https://erowid.org//chemicals/amphetamines/amphetamines.shtml Dextroamphetamine (Erowid Vault)]

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 {{SubstanceBox/Dextroamphetamine}}
-'''Dextroamphetamine''' (also known as '''Dexamphetamine''', '''D-Amphetamine''', '''Dex''', '''Dexies''', or by brand names including '''Adderall''', '''Attentin''', '''Dexedrine''') is a [[stimulant]] substance and the right-handed [[enantiomer]] of [[amphetamine]].
+'''Dextroamphetamine''' (also known as ''Dexamphetamine, Dex, Dexies'', and sold under brand names like ''[[Adderall]]'', ''[https://www.webmd.com/drugs/2/drug-1636-9080/dextroamphetamine-sulfate-oral/dextroamphetamine-oral/details Dexedrine]'', and ''[https://zenzedi.com/ Zenzedi]'') is a central nervous system stimulant and the right-handed enantiomer of amphetamine. It's more potent than its mirror twin, [https://en.wikipedia.org/wiki/Levoamphetamine levoamphetamine], especially in stimulating dopamine and [[Noradrenaline|norepinephrine]] activity in the brain.
-Dextroamphetamine is the more potent [[enantiomer]] of the two, but the effects are also slightly different in character. The small difference in affinity affects the mechanism resulting in a more mentally focused [[stimulation]] rather than physical, thus creating a [[stimulant]] that is more fit as a therapeutic drug rather than a recreational one. Therefore, the dextrorotatory enantiomer is preferred in treatment of attention deficit hyperactivity disorder, whereas a [[racemic]] mixture like [[amphetamine]] is found when sold on the streets.
+[[Subjective effects]] include [[stimulation]], increased focus, [[Motivation enhancement|motivation enhancement]], [[Appetite suppression|appetite suppression]], [[wakefulness]], [[Thought acceleration|thought acceleration]], and [[euphoria]]. At lower to moderate doses, it can promote productivity, alertness, and sociability. However, higher doses may induce restlessness, anxiety, compulsive redosing, and over-stimulation. It is classified as a classical stimulant due to its ability to promote mental and physical arousal through increased catecholamine activity.
+A notable property of dextroamphetamine is its high potential for abuse and rapid tolerance buildup. Repeated use over short periods can lead to diminished effects, compulsive use patterns, and a pronounced comedown characterized by [https://en.wikipedia.org/wiki/Fatigue#Mental mental fatigue], [[irritability]], and [[anhedonia]].
+Recreational or street amphetamine is usually a racemic mix of both enantiomers, resulting in a broader and less focused effect profile compared to pure dextroamphetamine.
 It is highly advised to use [[Harm reduction practices|harm reduction practices]] if using this substance.
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 ==See also==
 *[[Responsible use]]
 *[[Stimulant]]
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 ==External links==
 *[[wikipedia:Dextroamphetamine|Dextroamphetamine (Wikipedia)]]
 *[https://erowid.org//chemicals/amphetamines/amphetamines.shtml Dextroamphetamine (Erowid Vault)]