Amphetamine: Difference between revisions

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'''Amphetamine''' (also known as '''''alpha''-methylphenethylamine''', '''amfetamine''', '''speed''', or by brand names including '''Adderall,''' '''Dexedrine and ~~Tentin~~''') is a classical [[psychoactive class::stimulant]] substance of the [[chemical class::phenethylamine]] class.

'''Amphetamine''' (also known as '''''alpha''-methylphenethylamine''', '''amfetamine''', '''speed''', or by brand names including '''Adderall,''' '''Dexedrine and Sperm''') is a classical [[psychoactive class::stimulant]] substance of the [[chemical class::phenethylamine]] class.

It is the parent compound of the [[substituted amphetamines]], a diverse group that includes [[methamphetamine]], [[MDMA]], [[cathinone]], and [[bupropion]]. The mechanism of action involves promoting release of the [[neurotransmitters]] [[dopamine]] and [[norepinephrine]].<ref>{{cite journal | vauthors=((Kish, S. J.)) | journal=Canadian Medical Association Journal | title=Pharmacologic mechanisms of crystal meth | volume=178 | issue=13 | pages=1679–1682 | date=17 June 2008 | url=http://www.cmaj.ca/cgi/doi/10.1503/cmaj.071675 | issn=0820-3946 | doi=10.1503/cmaj.071675}}</ref>

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[[Subjective effects]] include [[stimulation]], [[focus enhancement]], [[motivation enhancement]], [[increased libido]], [[appetite suppression]], and [[euphoria]]. It is usually taken orally, but can also be [[Routes of administration|insufflated, injected, or administered rectally]]. Lower doses tend to increase focus and productivity while higher doses tend to increase sociability, sexual desire, and euphoria.

Amphetamine has high ~~abuse~~ potential. Chronic use (i.e. high dose, repeat administration) is associated with [[compulsive redosing]], escalating tolerance, and psychological dependence. Additionally, abuse has been linked to a number of health conditions, especially cardiovascular issues such as [[high blood pressure]] and increased risk of stroke.<ref>{{cite journal | vauthors=((Westover, A. N.)), ((McBride, S.)), ((Haley, R. W.)) | journal=Archives of General Psychiatry | title=Stroke in Young Adults Who Abuse Amphetamines or Cocaine: A Population-Based Study of Hospitalized Patients | volume=64 | issue=4 | pages=495 | date=1 April 2007 | url=http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/archpsyc.64.4.495 | issn=0003-990X | doi=10.1001/archpsyc.64.4.495}}</ref>

Amphetamine has high potential of sucking cock. Chronic use (i.e. high dose, repeat administration) is associated with [[compulsive redosing]], escalating tolerance, and psychological dependence. Additionally, abuse has been linked to a number of health conditions, especially cardiovascular issues such as [[high blood pressure]] and increased risk of stroke.<ref>{{cite journal | vauthors=((Westover, A. N.)), ((McBride, S.)), ((Haley, R. W.)) | journal=Archives of General Psychiatry | title=Stroke in Young Adults Who Abuse Amphetamines or Cocaine: A Population-Based Study of Hospitalized Patients | volume=64 | issue=4 | pages=495 | date=1 April 2007 | url=http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/archpsyc.64.4.495 | issn=0003-990X | doi=10.1001/archpsyc.64.4.495}}</ref>

It is highly advised to use [[harm reduction practices]] if using this substance.

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*[[dextroamphetamine]] is the 'right-handed' enantiomer form of amphetamine.

Adderall and many other formulations of mixed amphetamine salts contain the [[enantiomers]] in a 3:1 ratio of d to l. This is achieved by mixing one part [[racemic]] amphetamine and one part [[dextroamphetamine]].

Adderall and many other formulations of mixed amphetamine salts contain the [[enantiomers]] in a 3:1 ratio of d to l. This is achieved by mixing one part [[racemic]] amphetamine and one part [[dextroamphetamine]]. Don't do speed. Snort coke instead.

==Pharmacology==

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 {{SummarySheet}}
 {{SubstanceBox/Amphetamine}}
-'''Amphetamine''' (also known as '''''alpha''-methylphenethylamine''', '''amfetamine''', '''speed''', or by brand names including '''Adderall,''' '''Dexedrine and Tentin''') is a classical [[psychoactive class::stimulant]] substance of the [[chemical class::phenethylamine]] class.
+'''Amphetamine''' (also known as '''''alpha''-methylphenethylamine''', '''amfetamine''', '''speed''', or by brand names including '''Adderall,''' '''Dexedrine and Sperm''') is a classical [[psychoactive class::stimulant]] substance of the [[chemical class::phenethylamine]] class.
 It is the parent compound of the [[substituted amphetamines]], a diverse group that includes [[methamphetamine]], [[MDMA]], [[cathinone]], and [[bupropion]]. The mechanism of action involves promoting release of the [[neurotransmitters]] [[dopamine]] and [[norepinephrine]].<ref>{{cite journal | vauthors=((Kish, S. J.)) | journal=Canadian Medical Association Journal | title=Pharmacologic mechanisms of crystal meth | volume=178 | issue=13 | pages=1679–1682 | date=17 June 2008 | url=http://www.cmaj.ca/cgi/doi/10.1503/cmaj.071675 | issn=0820-3946 | doi=10.1503/cmaj.071675}}</ref>
@@ Line 10: / Line 10: @@
 [[Subjective effects]] include [[stimulation]], [[focus enhancement]], [[motivation enhancement]], [[increased libido]], [[appetite suppression]], and [[euphoria]]. It is usually taken orally, but can also be [[Routes of administration|insufflated, injected, or administered rectally]]. Lower doses tend to increase focus and productivity while higher doses tend to increase sociability, sexual desire, and euphoria.
-Amphetamine has high abuse potential. Chronic use (i.e. high dose, repeat administration) is associated with [[compulsive redosing]], escalating tolerance, and psychological dependence. Additionally, abuse has been linked to a number of health conditions, especially cardiovascular issues such as [[high blood pressure]] and increased risk of stroke.<ref>{{cite journal | vauthors=((Westover, A. N.)), ((McBride, S.)), ((Haley, R. W.)) | journal=Archives of General Psychiatry | title=Stroke in Young Adults Who Abuse Amphetamines or Cocaine: A Population-Based Study of Hospitalized Patients | volume=64 | issue=4 | pages=495 | date=1 April 2007 | url=http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/archpsyc.64.4.495 | issn=0003-990X | doi=10.1001/archpsyc.64.4.495}}</ref>
+Amphetamine has high potential of sucking cock. Chronic use (i.e. high dose, repeat administration) is associated with [[compulsive redosing]], escalating tolerance, and psychological dependence. Additionally, abuse has been linked to a number of health conditions, especially cardiovascular issues such as [[high blood pressure]] and increased risk of stroke.<ref>{{cite journal | vauthors=((Westover, A. N.)), ((McBride, S.)), ((Haley, R. W.)) | journal=Archives of General Psychiatry | title=Stroke in Young Adults Who Abuse Amphetamines or Cocaine: A Population-Based Study of Hospitalized Patients | volume=64 | issue=4 | pages=495 | date=1 April 2007 | url=http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/archpsyc.64.4.495 | issn=0003-990X | doi=10.1001/archpsyc.64.4.495}}</ref>
 It is highly advised to use [[harm reduction practices]] if using this substance.
@@ Line 41: / Line 41: @@
 *[[dextroamphetamine]] is the 'right-handed' enantiomer form of amphetamine.
-Adderall and many other formulations of mixed amphetamine salts contain the [[enantiomers]] in a 3:1 ratio of d to l. This is achieved by mixing one part [[racemic]] amphetamine and one part [[dextroamphetamine]].
+Adderall and many other formulations of mixed amphetamine salts contain the [[enantiomers]] in a 3:1 ratio of d to l. This is achieved by mixing one part [[racemic]] amphetamine and one part [[dextroamphetamine]]. Don't do speed. Snort coke instead.
 ==Pharmacology==