Talk:2-MMC: Difference between revisions
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{{SummarySheet}} | {{SummarySheet}} | ||
{{SubstanceBox/2-MMC}} | {{SubstanceBox/2-MMC}} | ||
'''2-Methylmethcathinone''' (also known as '''2-MMC''', '''Ortho''' or '''Orthomephedrone''') is a novel lesser-known stimulant-entactogen substance of the [[cathinones|cathinone]] class that induces feelings of euphoria, and stimulation. It is related to other substituted cathinones like for example [[3-MMC]] or [[4-MMC]] (Mephedrone). The mechanism of action is not fully studied, but [[dopamine]] | '''2-Methylmethcathinone''' (also known as '''2-MMC''', '''Ortho''' or '''Orthomephedrone''') is a novel lesser-known stimulant-entactogen substance of the [[cathinones|cathinone]] class that induces feelings of [[physical euphoria|euphoria]], and [[stimulation]]. It is related to other substituted cathinones like for example [[3-MMC]] or [[4-MMC]] (Mephedrone). The mechanism of action is not fully studied, but [[dopamine]] ,[[serotonin]] and [[norepinephrine]] releasing activity is known to be involved. | ||
,[[serotonin]] and [[norepinephrine]] releasing activity is known to be involved. | |||
2-MMC is shown to be more dopaminergic and less serotonergic compared to [[MDMA]]. This profile makes it more stimulating and less empathogenic, similar to that of [[Amphetamine]]. | 2-MMC is shown to be more dopaminergic and less serotonergic compared to [[MDMA]]. This profile makes it more stimulating and less empathogenic, similar to that of [[Amphetamine]]. | ||
[[Subjective effects]] include [[stimulation]], [[anxiety suppression]], [[empathy, affection, and sociability enhancement|enhanced empathy and sociability]], [[muscle relaxation|relaxation]], [[increased libido]], [[increased music appreciation]] and [[euphoria]]. The effects are reported to be a mix of amphetamine and a cocaine-like stimulation rush with a lighter version of MDMA euphoria. | [[Subjective effects]] include [[stimulation]], [[anxiety suppression]], [[empathy, affection, and sociability enhancement|enhanced empathy and sociability]], [[muscle relaxation|relaxation]], [[increased libido]], [[increased music appreciation]] and [[euphoria]]. The effects are reported to be a mix of amphetamine and a cocaine-like stimulation rush with a lighter version of MDMA euphoria. | ||
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|{{effects/physical| | |{{effects/physical| | ||
*'''[[Effect::Stimulation]]''' - Orthomephedrone is reported to be highly energizing and stimulating, it encourages physical activities like running, walking, or dancing. The style of stimulation can be described as "forced". This means that at higher doses, it becomes difficult or impossible to keep still as jaw clenching, involuntarily body shakes and vibrations become present. Additionally, | *'''[[Effect::Stimulation]]''' - Orthomephedrone is reported to be highly energizing and stimulating, it encourages physical activities like running, walking, or dancing. The style of stimulation can be described as "forced". This means that at higher doses, it becomes difficult or impossible to keep still as jaw clenching, involuntarily body shakes and vibrations become present. Additionally, wave-like feelings of sedation and relaxation may be paradoxically present, although this doesnt happen that frequently as on [[3-MMC]], it can lead users to redose. | ||
*'''[[Effect::Physical euphoria]]''' | |||
*'''[[Effect::Stamina enhancement]]''' | |||
*'''[[Effect::Bodily control enhancement]]''' | *'''[[Effect::Bodily control enhancement]]''' | ||
*'''[[Effect::Temperature regulation suppression]]''' | *'''[[Effect::Temperature regulation suppression]]''' | ||
*'''[[Effect::Spontaneous physical sensations]]''' | *'''[[Effect::Spontaneous physical sensations]]''' | ||
*'''[[Effect::Increased bodily temperature]]''' & *'''[[Effect::Decreased bodily temperature]]''' | *'''[[Effect::Increased bodily temperature]]''' & *'''[[Effect::Decreased bodily temperature]]''' | ||
*'''[[Effect::Increased perspiration]]''' | *'''[[Effect::Increased perspiration]]''' | ||
*'''[[Effect::Abnormal heartbeat]]''' | |||
*'''[[Effect::Increased heart rate]]''' - 2-MMC increases heart rate mildly to moderately compared to other stimulants. | |||
*'''[[Effect::Vasoconstriction]]''' | *'''[[Effect::Vasoconstriction]]''' | ||
*'''[[Effect:: | *'''[[Effect::Dry mouth]]''' | ||
*'''[[Effect::Dehydration]]''' | *'''[[Effect::Dehydration]]''' | ||
*'''[[Effect:: | *'''[[Effect::Vibrating vision]]''' - At overly high dosages or binging a person's eyeballs may begin to spontaneously wiggle back and forth in a rapid motion, causing the vision to become blurry and temporarily out of focus. This is a condition known as [http://en.wikipedia.org/wiki/Nystagmus nystagmus]. | ||
*'''[[Effect::Frequent urination]]''' | *'''[[Effect::Frequent urination]]''' | ||
*'''[[Effect::Tactile intensification]]''' | *'''[[Effect::Tactile intensification]]''' | ||
*'''[[Effect::Appetite suppression]]''' | *'''[[Effect::Appetite suppression]]''' | ||
*'''[[Effect::Pupil dilation]]''' | *'''[[Effect::Pupil dilation]]''' | ||
*'''[[Effect::Teeth grinding]]''' - This component can be considered to be less intense when compared with that of [[MDMA]]. | *'''[[Effect::Teeth grinding]]''' - This component can be considered to be less intense when compared with that of [[MDMA]]. | ||
*'''[[Effect::Restless leg syndrome]]''' | |||
*'''[[Effect::Orgasm depression]]''' | *'''[[Effect::Orgasm depression]]''' | ||
*'''[[Effect::Temporary erectile dysfunction]]''' | *'''[[Effect::Temporary erectile dysfunction]]''' | ||
*'''[[Effect::Seizure]]''' - This is a very rare effect but can likely happen in those predisposed to them, especially while in physically taxing conditions such as being dehydrated, undernourished, overheated, fatigued or when combining with other substances that lower the seizure threshold. | *'''[[Effect::Seizure]]''' - This is a very rare effect but can likely happen in those predisposed to them, especially while in physically taxing conditions such as being dehydrated, undernourished, overheated, fatigued or when combining with other substances that lower the seizure threshold. | ||
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{{effects/cognitive| | {{effects/cognitive| | ||
*'''[[Effect::Analysis enhancement]]''' | |||
*'''[[Effect::Anxiety suppression]] | *'''[[Effect::Anxiety suppression]] | ||
*'''[[Effect::Cognitive euphoria]]''' | *'''[[Effect::Cognitive euphoria]]''' | ||
*'''[[Effect:: | *'''[[Effect::Creativity enhancement]]''' | ||
*'''[[Effect::Compulsive redosing]]''' | |||
*'''[[Effect::Disinhibition]] | *'''[[Effect::Disinhibition]] | ||
*'''[[Effect::Delusion]]''' | |||
*'''[[Effect::Empathy, affection, and sociability enhancement]] | *'''[[Effect::Empathy, affection, and sociability enhancement]] | ||
*'''[[Effect::Ego inflation]] | *'''[[Effect::Ego inflation]] | ||
*'''[[Effect::Increased music appreciation]]''' | *'''[[Effect::Increased music appreciation]]''' | ||
*'''[[Effect::Immersion enhancement]]''' | *'''[[Effect::Immersion enhancement]]''' | ||
*'''[[Effect::Increased libido]]''' | *'''[[Effect::Increased libido]]''' | ||
*'''[[Effect::Memory suppression]]''' - 2-MMC's positional isomer [[4-MMC]] has been shown to negatively impact short-term memory<ref>https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0045473</ref> and 2-MMC itself anecdotally is said to have immediate disruptive effects on memory. | *'''[[Effect::Memory suppression]]''' - 2-MMC's positional isomer [[4-MMC]] has been shown to negatively impact short-term memory<ref>https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0045473</ref> and 2-MMC itself anecdotally is said to have immediate disruptive effects on memory. | ||
*'''[[Effect::Motivation enhancement]]''' | *'''[[Effect::Motivation enhancement]]''' | ||
*'''[[Effect::Thought acceleration]]''' | *'''[[Effect::Thought acceleration]]''' | ||
*'''[[Effect::Delirium]]''' & '''[[Effect::Confusion]]''' - This effect typically only occurs with overly high doses, and is associated with temperature dysregulation, sleep deprivation and overheating, particularly when 2-MMC is taken in crowded, physically strenuous environments that leaves the user unable to cool off, rest, or rehydrate adequately. | *'''[[Effect::Delirium]]''' & '''[[Effect::Confusion]]''' - This effect typically only occurs with overly high doses, and is associated with temperature dysregulation, sleep deprivation and overheating, particularly when 2-MMC is taken in crowded, physically strenuous environments that leaves the user unable to cool off, rest, or rehydrate adequately. | ||
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The effects which occur during the [[offset]] of a [[stimulant]] experience generally feel negative and uncomfortable in comparison to the effects which occurred during its [[peak]]. This is often referred to as a "comedown" and occurs because of [[neurotransmitter]] depletion. Its effects commonly include: | The effects which occur during the [[offset]] of a [[stimulant]] experience generally feel negative and uncomfortable in comparison to the effects which occurred during its [[peak]]. This is often referred to as a "comedown" and occurs because of [[neurotransmitter]] depletion. Its effects commonly include: | ||
*'''[[Effect::Appetite | *'''[[Effect::Appetite suppression]]''' | ||
*'''[[Effect::Cognitive fatigue]]''' | *'''[[Effect::Cognitive fatigue]]''' | ||
*'''[[Effect::Delusion]]''' | *'''[[Effect::Delusion]]''' |