Ibotenic acid: Difference between revisions

>Graham
m wiki ref formatting
>Clandestine
m Clarified that the neurotoxicity of ibotenic acid has not been studied in humans.
Line 3: Line 3:
'''Ibotenic acid''' or '''(''S'')-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid''' (also referred to as '''ibotenate''') is a psychoactive substance which occurs naturally in ''[[Amanita muscaria]]'' and related species of mushrooms. It is an analogue of the neurotransmitter [[glutamate]], and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist.{{citation needed}}
'''Ibotenic acid''' or '''(''S'')-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid''' (also referred to as '''ibotenate''') is a psychoactive substance which occurs naturally in ''[[Amanita muscaria]]'' and related species of mushrooms. It is an analogue of the neurotransmitter [[glutamate]], and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist.{{citation needed}}


Ibotenic acid can be a powerful neurotoxin, and is employed as a "brain-lesioning agent" through cranial injections in scientific research.{{citation needed}}
Ibotenic acid is a powerful neurotoxin, and has been employed as a "brain-lesioning agent" through cranial injections in scientific research conducted in rats.{{citation needed}} The same properties have not been studied in humans, however it could very well be a human neurotoxin as well.


==Chemistry==
==Chemistry==