Talk:Etorphine: Difference between revisions

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{{decree|type=warning|message=This substance is extraordinarily potent, approximately 1,000–3,000 times that of morphine.(i.e. active in the microgram range). For this reason, it should be handled with extreme care and never be eyeballed. Etorphine can also be fatal when combined with depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, thienodiazepines or other GABAergic substances.[1]

It is strongly encouraged to wear gloves while handling, use volumetric dosing combined with a milligram scale, and to not consume either moderate or heavy dosages of other depressants in combination with this drug (i.e. active in the microgram range). For this reason, it should be handled with extreme care and never be eyeballed. Etorphine can also be fatal when combined with depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, thienodiazepines or other GABAergic substances.[1]

It is strongly encouraged to wear gloves while handling, use volumetric dosing combined with a milligram scale, and to not consume either moderate or heavy dosages of other depressants in combination with this drug. .}}

{{headerpanel|{{Etorphine}}}}

Etorphine is an alcohol and a morphinane alkaloid. It has a role as an opioid analgesic, a sedative and an opioid receptor agonist.

Etorphine is a DEA Schedule I controlled substance. Substances in the DEA Schedule I have no currently accepted medical use in the United States, a lack of accepted safety for use under medical supervision, and a high potential for abuse. Etorphine (also called M-99, aka what is used in the popular show Dexter) is a narcotic analgesic morphinan used as a sedative in veterinary practice. In certain countries, etorphine is classified as a Schedule 1 drug and hence, in these countries, it can be used legally only by health professionals and for research purposes. Etorphine is only available to the patients under an official prescription. In the US, Etorphine is listed as a Schedule I drug, although Etorphine hydrochloride is classified as Schedule II.

{{decree|type=notice|message=This article is in the 'Talk' namespace because it is an unfinished draft. This section is used to host drafts for unpublished articles as well as discussions for published ones. If you'd like to use this area to discuss this draft, please do so in the 'Discussion' section at the very bottom of the page. This notice will be removed once this draft has been approved for publication by an administrator.}}

For tips on how to properly format a substance article, please refer to this document: [[Content Style Guide - Substance]]

==History and culture==

'''Etorphine''' (also known as '''M-99''') is a potent [[Psychoactive class::opioid]] substance of the [[Chemical class::alcohol and a morphinane alkaloid]] class.

[[Subjective effects]] are similar to those of [[heroin]] and includes [[pain relief]] (analgesia), [[sedation]], [[respiratory depression]], and [[euphoria]]. However, it has a rapid [[onset]] and short [[duration]] of action relative to other opioids, which can lead to [[compulsive redosing]].

Etorphine is a highly dangerous substance due its addictiveness and the difficulty with which it can be safely dosed, a result of its incredible potency. Users are advised to be aware of the extreme risk they are placing themselves in if they choose to use Etorphine. Users should take EXTREME caution using this substance.

==Chemistry==

==Pharmacology==

==Subjective effects==

{{effects/base

|{{effects/physical|

If applicable, a brief paragraph summary of the substance's physical effects may be included here.

You may select physical effects to add below [[Subjective effect index#Physical effects|here]].

*'''[[Effect::Physical effect]]'''

*'''[[Effect::Physical effect2]]'''

*'''[[Effect::Physical effect3]]'''

}}

{{effects/visual|

If applicable, a brief paragraph summary of the substance's visual effects may be included here.

You may select visual effects to add below [[Subjective effect index#Visual effects|here]].

====Enhancements====

*'''[[Effect::Visual acuity effect1]]'''

====Distortions====

*'''[[Effect::Visual distortion effect1]]'''

====[[Effect::Geometry]]====

If applicable, a brief paragraph summary describing the visual geometry produced by the substance may be included here.

====Hallucinatory states====

If applicable, a brief summary of the substance's visual effects profile may be written here.

*'''[[Effect::Hallucinatory states1]]'''

}}

|{{effects/cognitive|

If applicable, a brief paragraph summary of the substance's cognitive effects may be included here.

You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].

*'''[[Effect::Cognitive effect1]]'''

*'''[[Effect::Cognitive effect2]]'''

*'''[[Effect::Cognitive effect3]]'''

}}

{{effects/auditory|

If applicable, a brief paragraph summary of the substance's auditory effects may be included here.

You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].

*'''[[Effect::Auditory effect1]]'''

*'''[[Effect::Auditory effect2]]'''

}}

{{effects/multisensory|

If applicable, a brief paragraph summary of the substance's multisensory effects may be included here.

You may select from a list of multisensory effects to add below [[Subjective effect index#Multisensory effects|here]].

*'''[[Effect::Multisensory effect1]]'''

*'''[[Effect::Multisensory effect2]]'''

}}

{{effects/transpersonal|

If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here.

You may select from a list of transpersonal effects to add below [[Subjective effect index#Transpersonal effects|here]].

*'''[[Effect::Transpersonal effect1]]'''

*'''[[Effect::Transpersonal effect2]]'''

}}

===Experience reports===

{{Experience reports|SUBSTANCE|https://www.erowid.org/experiences/subs/exp_SUBSTANCE.shtml}}

==Toxicity and harm potential==

It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.

===Lethal dosage===

===Tolerance and addiction potential===

===Dangerous interactions===

==Legal status==

==See also==

*[[Responsible use]]

==External links==

(List along order below)

*[https://en.wikipedia.org/wiki/SUBSTANCE SUBSTANCE (Wikipedia)]

*SUBSTANCE (Erowid Vault)

*SUBSTANCE ([''PiHKAL'' or ''TiHKAL''] / Isomer Design)

==Literature==

*APA formatted reference

Please see the [[citation formatting guide]] if you need assistance properly formatting citations.

==References==

[[Category:Psychoactive substance]]

[[Category:Proofread]]

[[Category:Approval]]

[[Category:Opioid]]

[[Category:Alcohol]]

__INDEX__

@@ Line 1: / Line 1: @@
-{{DISPLAYTITLE:Etorphine (M-99)}}
+{{decree|type=warning|message=This substance is extraordinarily potent, approximately 1,000–3,000 times that of morphine.(i.e. active in the microgram range). For this reason, it should be handled with extreme care and never be eyeballed. Etorphine can also be fatal when combined with depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, thienodiazepines or other GABAergic substances.[1]
+It is strongly encouraged to wear gloves while handling, use volumetric dosing combined with a milligram scale, and to not consume either moderate or heavy dosages of other depressants in combination with this drug (i.e. active in the microgram range). For this reason, it should be handled with extreme care and never be eyeballed. Etorphine can also be fatal when combined with depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, thienodiazepines or other GABAergic substances.[1]
+It is strongly encouraged to wear gloves while handling, use volumetric dosing combined with a milligram scale, and to not consume either moderate or heavy dosages of other depressants in combination with this drug. .}}
+{{headerpanel|{{Etorphine}}}}
+{{SummarySheet}}
+{{SubstanceBox/Etorphine}}
 Etorphine is an alcohol and a morphinane alkaloid. It has a role as an opioid analgesic, a sedative and an opioid receptor agonist.
 Etorphine is a DEA Schedule I controlled substance. Substances in the DEA Schedule I have no currently accepted medical use in the United States, a lack of accepted safety for use under medical supervision, and a high potential for abuse. Etorphine (also called M-99, aka what is used in the popular show Dexter) is a narcotic analgesic morphinan used as a sedative in veterinary practice. In certain countries, etorphine is classified as a Schedule 1 drug and hence, in these countries, it can be used legally only by health professionals and for research purposes. Etorphine is only available to the patients under an official prescription. In the US, Etorphine is listed as a Schedule I drug, although Etorphine hydrochloride is classified as Schedule II.
+{{decree|type=notice|message=This article is in the 'Talk' namespace because it is an unfinished draft. This section is used to host drafts for unpublished articles as well as discussions for published ones. If you'd like to use this area to discuss this draft, please do so in the 'Discussion' section at the very bottom of the page. This notice will be removed once this draft has been approved for publication by an administrator.}}
+<!-- Please ensure that any new substance articles are first published in the 'Talk' namespace. For example, a new article on substance XYZ should have the title "Talk: XYZ" instead of "XYZ". Once the submitted article has been reviewed and determined to meet the guidelines and standards, it will be published by a staff member. -->
+For tips on how to properly format a substance article, please refer to this document: [[Content Style Guide - Substance]]
+==History and culture==
+{{historyStub}}
+'''Etorphine''' (also known as '''M-99''') is a potent [[Psychoactive class::opioid]] substance of the [[Chemical class::alcohol and a morphinane alkaloid]] class.
+[[Subjective effects]] are similar to those of [[heroin]] and includes [[pain relief]] (analgesia), [[sedation]], [[respiratory depression]], and [[euphoria]]. However, it has a rapid [[onset]] and short [[duration]] of action relative to other opioids, which can lead to [[compulsive redosing]].
+Etorphine is a highly dangerous substance due its addictiveness and the difficulty with which it can be safely dosed, a result of its incredible potency. Users are advised to be aware of the extreme risk they are placing themselves in if they choose to use Etorphine. Users should take EXTREME caution using this substance.
+==Chemistry==
+{{chemistry}}
+==Pharmacology==
+{{pharmacology}}
+==Subjective effects==
+{{EffectStub}}
+{{Preamble/SubjectiveEffects}}
+{{effects/base
+|{{effects/physical|
+If applicable, a brief paragraph summary of the substance's physical effects may be included here.
+You may select physical effects to add below [[Subjective effect index#Physical effects|here]].
+*'''[[Effect::Physical effect]]'''
+*'''[[Effect::Physical effect2]]'''
+*'''[[Effect::Physical effect3]]'''
+}}
+{{effects/visual|
+If applicable, a brief paragraph summary of the substance's visual effects may be included here.
+You may select visual effects to add below [[Subjective effect index#Visual effects|here]].
+====Enhancements====
+*'''[[Effect::Visual acuity effect1]]'''
+====Distortions====
+*'''[[Effect::Visual distortion effect1]]'''
+====[[Effect::Geometry]]====
+If applicable, a brief paragraph summary describing the visual geometry produced by the substance may be included here.
+====Hallucinatory states====
+If applicable, a brief summary of the substance's visual effects profile may be written here.
+*'''[[Effect::Hallucinatory states1]]'''
+}}
+|{{effects/cognitive|
+If applicable, a brief paragraph summary of the substance's cognitive effects may be included here.
+You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
+*'''[[Effect::Cognitive effect1]]'''
+*'''[[Effect::Cognitive effect2]]'''
+*'''[[Effect::Cognitive effect3]]'''
+}}
+{{effects/auditory|
+If applicable, a brief paragraph summary of the substance's auditory effects may be included here.
+You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].
+*'''[[Effect::Auditory effect1]]'''
+*'''[[Effect::Auditory effect2]]'''
+}}
+{{effects/multisensory|
+If applicable, a brief paragraph summary of the substance's multisensory effects may be included here.
+You may select from a list of multisensory effects to add below [[Subjective effect index#Multisensory effects|here]].
+*'''[[Effect::Multisensory effect1]]'''
+*'''[[Effect::Multisensory effect2]]'''
+}}
+{{effects/transpersonal|
+If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here.
+You may select from a list of transpersonal effects to add below [[Subjective effect index#Transpersonal effects|here]].
+*'''[[Effect::Transpersonal effect1]]'''
+*'''[[Effect::Transpersonal effect2]]'''
+}}
+}}
+===Experience reports===
+{{Experience reports|SUBSTANCE|https://www.erowid.org/experiences/subs/exp_SUBSTANCE.shtml}} <!-- Check the link to see if it exists -->
+==Toxicity and harm potential==
+{{toxicity}}
+It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
+===Lethal dosage===
+===Tolerance and addiction potential===
+===Dangerous interactions===
+{{DangerousInteractions}}
+{{DangerousInteractions/Intro}}
+==Legal status==
+{{LegalStub}}
+==See also==
+*[[Responsible use]]
+==External links==
+(List along order below)
+*[https://en.wikipedia.org/wiki/SUBSTANCE SUBSTANCE (Wikipedia)]
+*SUBSTANCE (Erowid Vault)
+*SUBSTANCE ([''PiHKAL'' or ''TiHKAL''] / Isomer Design)
+==Literature==
+*APA formatted reference
+Please see the [[citation formatting guide]] if you need assistance properly formatting citations.
+==References==
+<references />
+[[Category:Psychoactive substance]]
+[[Category:Proofread]]
+[[Category:Approval]]
 [[Category:Opioid]]
 [[Category:Alcohol]]
 __INDEX__