Talk:Kanna: Difference between revisions
>Corangl →Pharmacology: Description was inconsistent with research paper cited; the paper provides evidence that it upregulates VMAT-2, not inhibits it |
>Basedgod →History and culture: Fixed appetite suppression link |
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*'''[[Caffeine]]''' - Kanna is reported to have synergy with [[caffeine]], resulting in stronger [[stimulation]] with [[anxiety suppression|decreased anxiety]] and [[irritability]]. Other effects include an increased likelihood of [[cognitive euphoria]] and [[increased music appreciation]], both effects tending to be rather inconsistent when caffeine is consumed on its own. [[Tactile enhancement]] and [[visual acuity enhancement]] become quite prominent. It should be noted that both compounds are known to [[increased heart rate|increase heart rate]] and so caution should be used in determinig how often one uses these substances together and at what dose. Those with a weak heart should avoid this combination entirely. The [[empathy, affection and sociabilty enhancemnent|prosocial]] effects of kanna are more pronounced with this combo although the empathy and affection aspects are reduced. | *'''[[Caffeine]]''' - Kanna is reported to have synergy with [[caffeine]], resulting in stronger [[stimulation]] with [[anxiety suppression|decreased anxiety]] and [[irritability]]. Other effects include an increased likelihood of [[cognitive euphoria]] and [[increased music appreciation]], both effects tending to be rather inconsistent when caffeine is consumed on its own. [[Tactile enhancement]] and [[visual acuity enhancement]] become quite prominent. It should be noted that both compounds are known to [[increased heart rate|increase heart rate]] and so caution should be used in determinig how often one uses these substances together and at what dose. Those with a weak heart should avoid this combination entirely. The [[empathy, affection and sociabilty enhancemnent|prosocial]] effects of kanna are more pronounced with this combo although the empathy and affection aspects are reduced. | ||
*'''[[Substituted amphetamines|Amphetamines]]''' - Kanna has a strong synergy with amphetamines with effects ranging greatly based on its method of administration. Oral administration alleviates the [[stimulation|excess stimulation]], [[irritability]] and [[anxiety]] seen with high doses whilst reversing the [[emotion suppression|emotion suppresing]] effects of lower doses. The [[physical euphoria]] of both compounds is intensified greatly and the [[cognitive euphoria]] seen with higher doses is also greatly intensified. The effects of oral kanna on an amphetamine high can reliably make the experience feel more [[sedation|relaxing]] whilst decreasing (but not eliminating) the [[thought acceleration]] from the amphetamine. Effects that both compounds have in common such as [[brightness alteration]], [[stamina enhancement|increased stamina]] and [[increased music appreciation|music enhancement]] become far more pronounced. This holds true for negative side effects of both compounds as well such as [[increased perspiration]], [[dry mouth]], [[appetite suppression], [[vasoconstriction]], [[temporary erectile dysfunction]], [[difficulty urinating]] and [[frequent urination]], [[abnormal heartbeat]], [[increased heart rate]] and [[increased bodily temperature]], with these last three effects specifically, it should be comnsidered important that this combo is used sparingly. The [[empathy, affection and sociability enahancement|empathogenic effects]] of kanna are greatly enhanced with this combo, as are the [[tactile enhancement|tactile enhancements]] and visual effects such as [[color enhancement]], [[perspective distortions]] and [[depth perception distortions]]. [[Drifting]] from amphetamines is also more likely with the co-adminstartion of kanna although this rarely goes beyond level 2. Unique effects such as [[visual stretching]] and and low level [[visual disconnection]] is possible with this combo as well, especially if consumed during the amphetamine [[offset|comedown]]. | *'''[[Substituted amphetamines|Amphetamines]]''' - Kanna has a strong synergy with amphetamines with effects ranging greatly based on its method of administration. Oral administration alleviates the [[stimulation|excess stimulation]], [[irritability]] and [[anxiety]] seen with high doses whilst reversing the [[emotion suppression|emotion suppresing]] effects of lower doses. The [[physical euphoria]] of both compounds is intensified greatly and the [[cognitive euphoria]] seen with higher doses is also greatly intensified. The effects of oral kanna on an amphetamine high can reliably make the experience feel more [[sedation|relaxing]] whilst decreasing (but not eliminating) the [[thought acceleration]] from the amphetamine. Effects that both compounds have in common such as [[brightness alteration]], [[stamina enhancement|increased stamina]] and [[increased music appreciation|music enhancement]] become far more pronounced. This holds true for negative side effects of both compounds as well such as [[increased perspiration]], [[dry mouth]], [[appetite suppression]], [[vasoconstriction]], [[temporary erectile dysfunction]], [[difficulty urinating]] and [[frequent urination]], [[abnormal heartbeat]], [[increased heart rate]] and [[increased bodily temperature]], with these last three effects specifically, it should be comnsidered important that this combo is used sparingly. The [[empathy, affection and sociability enahancement|empathogenic effects]] of kanna are greatly enhanced with this combo, as are the [[tactile enhancement|tactile enhancements]] and visual effects such as [[color enhancement]], [[perspective distortions]] and [[depth perception distortions]]. [[Drifting]] from amphetamines is also more likely with the co-adminstartion of kanna although this rarely goes beyond level 2. Unique effects such as [[visual stretching]] and and low level [[visual disconnection]] is possible with this combo as well, especially if consumed during the amphetamine [[offset|comedown]]. | ||
*'''[[Alcohol]]''' - Kanna is reported to have strong synergy with [[alcohol]], increasing the [[empathy, affection and sociability enhancement|prococial effects]] of both substances as well as providing a strong sense of [[novelty enhancement]] and [[unity and interconnectedness|appreciation for nature]]. The warm body feelings of kanna are enhanced greatly with this combination, as are typical empathogenic desires for physical effection. Negative drawbacks to alcohol consumption such as [[irritability]] and [[tactile suppression]] are reduced whilst feelings of [[pain relief]], [[muscle relaxation]] and [[motor control loss]] become more pronounced. [[Nausea]] and heartburn may be more of a risk for sensitive individuals and so those with a weak stomach should be cautious with their dosing. The visual effects of kanna are mostly reduced to [[color enhancement]] and a [[visual haze]] as the effects of alcohol seem to negate some of kanna's more hallucinogenic visual effects. It has been shown that SSRIs increase sensitivity to alcohol and may make the compound more neurotoxic than if it were taken on its own. For this reason, it is advised to use this combo sparingly if one should choose to try it | *'''[[Alcohol]]''' - Kanna is reported to have strong synergy with [[alcohol]], increasing the [[empathy, affection and sociability enhancement|prococial effects]] of both substances as well as providing a strong sense of [[novelty enhancement]] and [[unity and interconnectedness|appreciation for nature]]. The warm body feelings of kanna are enhanced greatly with this combination, as are typical empathogenic desires for physical effection. Negative drawbacks to alcohol consumption such as [[irritability]] and [[tactile suppression]] are reduced whilst feelings of [[pain relief]], [[muscle relaxation]] and [[motor control loss]] become more pronounced. [[Nausea]] and heartburn may be more of a risk for sensitive individuals and so those with a weak stomach should be cautious with their dosing. The visual effects of kanna are mostly reduced to [[color enhancement]] and a [[visual haze]] as the effects of alcohol seem to negate some of kanna's more hallucinogenic visual effects. It has been shown that SSRIs increase sensitivity to alcohol and may make the compound more neurotoxic than if it were taken on its own. For this reason, it is advised to use this combo sparingly if one should choose to try it |