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MAOI: Difference between revisions
>David Hedlund →List of MAOIs: ====''Banisteriopsis caapi''==== |
>David Hedlund →Tyramine: Tyramine and dopamine are metabolized by both MAO-A and MAO-B. It has been established that hypertensive crises are a consequence of MAO-A inhibition (Youdim et al. 1988; Laux et al. 1995).<ref>https://pubmed.ncbi.nlm.nih.gov/10063483/</ref> |
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===Tyramine=== | ===Tyramine=== | ||
Tyramine is physiologically metabolized by monamine oxidases (primarily MAO-A), FMO3, PNMI, DBH and CYP2D6.<ref>https://www.ajol.info/index.php/jomip/article/view/213795</ref><ref>https://pubmed.ncbi.nlm.nih.gov/31736764/</ref> However, eating foods rich in tyramine while taking high doses of MAO-B inhibitors can cause a sudden increase in blood pressure.<ref>https://www.parkinsons.org.uk/information-and-support/mao-b-inhibitors-rasagiline-selegiline-safinamide</ref> | Tyramine is physiologically metabolized by monamine oxidases (primarily MAO-A), FMO3, PNMI, DBH and CYP2D6.<ref>https://www.ajol.info/index.php/jomip/article/view/213795</ref><ref>https://pubmed.ncbi.nlm.nih.gov/31736764/</ref> Tyramine and dopamine are metabolized by both MAO-A and MAO-B. It has been established that hypertensive crises are a consequence of MAO-A inhibition (Youdim et al. 1988; Laux et al. 1995).<ref>https://pubmed.ncbi.nlm.nih.gov/10063483/</ref> However, eating foods rich in tyramine while taking high doses of MAO-B inhibitors can cause a sudden increase in blood pressure.<ref>https://www.parkinsons.org.uk/information-and-support/mao-b-inhibitors-rasagiline-selegiline-safinamide</ref> | ||
===Reversibility=== | ===Reversibility=== | ||