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Harmala alkaloid: Difference between revisions
>David Hedlund ==Examples==: Added ====Harmane==== 278px |
>David Hedlund →Examples: '''Harmane''' ('''harman''') is a MAO-A inhibitor. |
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====Harmane==== | ====Harmane==== | ||
[[File:Harmane_structure.svg|278px]] | [[File:Harmane_structure.svg|278px]] | ||
'''Harmane''' ('''harman''') is a MAO-A inhibitor.<ref name="pmid35832393">https://www.frontiersin.org/articles/10.3389/fnmol.2022.925272/full</ref><ref name="harman">{{cite journal |last1=Herraiz |first1=T |last2=Chaparro |first2=C |title=Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee. |journal=Life sciences |date=18 January 2006 |volume=78 |issue=8 |pages=795-802 |doi=10.1016/j.lfs.2005.05.074 |pmid=16139309}}</ref><!- Added to: MAOI, Harmala alkaloid --> | |||
====Harmine==== | ====Harmine==== | ||
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'''L-Tetrahydroharmine''' does not inhibit monoamine oxidase A. Instead, it weakly [[Reuptake inhibitor|inhibits reuptake]] of [[serotonin]]. | '''L-Tetrahydroharmine''' does not inhibit monoamine oxidase A. Instead, it weakly [[Reuptake inhibitor|inhibits reuptake]] of [[serotonin]]. | ||
'''D-THH''', on the other hand, has similar potency in terms of inhibiting MAO as harmine. | '''D-THH''', on the other hand, has similar potency in terms of inhibiting MAO as harmine. | ||
==Subjective effects== | ==Subjective effects== | ||
