Research chemicals: Difference between revisions

>Tracer
>David Hedlund
Opioids: See [https://isomerdesign.com/PiHKAL/tableLandscape.php?domain=pk&property=fentanyl&sort=name Isomer Design's fentanyl landscape] for a list of fentanyl analogs.
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====Opioids====
====Opioids====


*'''[[Acetylfentanyl]]''' - Between March 2013 and May 2013, 14 overdose deaths related to injected acetylfentanyl had occurred in Rhode Island. After confirming five overdoses in one county, including a fatality, Pennsylvania asked coroners and medical examiners across the state to screen for acetylfentanyl, which led to 50 confirmed fatalities and five non-fatal overdoses statewide in 2013.<ref>Ogilvie, Laurie, Christina Stanley, Lauren Lewis, Molly Boyd, Matthew Lozier, Matthew Lozier. "Notes from the Field: Acetyl Fentanyl Overdose Fatalities — Rhode Island, March–May 2013". cdc.gov. Center for Disease Control and Prevention. Retrieved 11 November 2013. | http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6234a5.htm</ref><ref>Pennsylvania Department of Drug and Alcohol Programs. "Department of Drug and Alcohol Programs warns about acetyl fentanyl: drug caused at least 50 fatalities in 2013 in Pennsylvania.". Pennsylvania Department of Drug and Alcohol Programs. | http://www.pa.gov/portal/server.pt/document/1345188/department_of_drug_and_alcohol_programs_warns_about_acetyl_fentanyl</ref> Another 5 deaths were reported in Jefferson Parish, New Orleans,<ref> Grunfeld, David (November 1, 2013). "Couple found dead in Old Metairie home killed by lethal new synthetic drug". NOLA.com | The Times-Picayune. Retrieved 28 March 2014. | http://www.nola.com/crime/index.ssf/2013/10/couple_found_dead_in_old_metai.html</ref> along with three more in North Carolina.<ref> "DHHS Issues Health Advisory for Deadly New Synthetic Drug". NC DHHS Press Releases. North Carolina Department of Health and Human Services. Retrieved 27 August 2014. | http://www.ncdhhs.gov/news/press-releases/dhhs-issues-health-advisory-deadly-new-synthetic-drug</ref>
*'''[[Acetylfentanyl]]''' - Between March 2013 and May 2013, 14 overdose deaths related to injected acetylfentanyl had occurred in Rhode Island. After confirming five overdoses in one county, including a fatality, Pennsylvania asked coroners and medical examiners across the state to screen for acetylfentanyl, which led to 50 confirmed fatalities and five non-fatal overdoses statewide in 2013.<ref>Ogilvie, Laurie, Christina Stanley, Lauren Lewis, Molly Boyd, Matthew Lozier, Matthew Lozier. "Notes from the Field: Acetyl Fentanyl Overdose Fatalities — Rhode Island, March–May 2013". cdc.gov. Center for Disease Control and Prevention. Retrieved 11 November 2013. | http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6234a5.htm</ref><ref>Pennsylvania Department of Drug and Alcohol Programs. "Department of Drug and Alcohol Programs warns about acetyl fentanyl: drug caused at least 50 fatalities in 2013 in Pennsylvania.". Pennsylvania Department of Drug and Alcohol Programs. | http://www.pa.gov/portal/server.pt/document/1345188/department_of_drug_and_alcohol_programs_warns_about_acetyl_fentanyl</ref> Another 5 deaths were reported in Jefferson Parish, New Orleans,<ref> Grunfeld, David (November 1, 2013). "Couple found dead in Old Metairie home killed by lethal new synthetic drug". NOLA.com | The Times-Picayune. Retrieved 28 March 2014. | http://www.nola.com/crime/index.ssf/2013/10/couple_found_dead_in_old_metai.html</ref> along with three more in North Carolina.<ref> "DHHS Issues Health Advisory for Deadly New Synthetic Drug". NC DHHS Press Releases. North Carolina Department of Health and Human Services. Retrieved 27 August 2014. | http://www.ncdhhs.gov/news/press-releases/dhhs-issues-health-advisory-deadly-new-synthetic-drug</ref> See [https://isomerdesign.com/PiHKAL/tableLandscape.php?domain=pk&property=fentanyl&sort=name Isomer Design's fentanyl landscape] for a list of fentanyl analogs.
*'''[[AH-7921]]'''- In a 2014 study which investigated nine fatalities in which AH-7921 was involved, it was concluded that poly-drug use was not a major contributing factor for the deaths and that a more important factor was the person's tolerance to opiates, which led to an overdose when the drug was taken in excessive amounts.<ref>Fatal Intoxications Associated with the Designer Opioid AH-7921 | http://jat.oxfordjournals.org/content/38/8/599.full</ref>
*'''[[AH-7921]]'''- In a 2014 study which investigated nine fatalities in which AH-7921 was involved, it was concluded that poly-drug use was not a major contributing factor for the deaths and that a more important factor was the person's tolerance to opiates, which led to an overdose when the drug was taken in excessive amounts.<ref>Fatal Intoxications Associated with the Designer Opioid AH-7921 | http://jat.oxfordjournals.org/content/38/8/599.full</ref>
*'''[[U-47700]]''' - Combined consumption of U-47700 and [[fentanyl]] caused one fatality in Belgium.<ref>Twee doden in België door overdosis met fentanylpleisters | http://deredactie.be/cm/vrtnieuws/binnenland/1.2558454</ref> Individual consumption of U-47700 caused one fatality in Ireland.<ref>U-47700 death | http://www.thejournal.ie/readme/opinion-our-drug-policy-isnt-working-and-people-are-dying-3200883-Jan2017</ref> At least 17 opioid overdoses and several deaths in the USA have also been connected with the use of U-47700.<ref>Synthetic opiate makers stay step ahead of US drug laws as overdose cases rise (the guardian) | http://www.theguardian.com/world/2016/apr/11/synthetic-opiates-drug-laws-w-18-fentanyl</ref>
*'''[[U-47700]]''' - Combined consumption of U-47700 and [[fentanyl]] caused one fatality in Belgium.<ref>Twee doden in België door overdosis met fentanylpleisters | http://deredactie.be/cm/vrtnieuws/binnenland/1.2558454</ref> Individual consumption of U-47700 caused one fatality in Ireland.<ref>U-47700 death | http://www.thejournal.ie/readme/opinion-our-drug-policy-isnt-working-and-people-are-dying-3200883-Jan2017</ref> At least 17 opioid overdoses and several deaths in the USA have also been connected with the use of U-47700.<ref>Synthetic opiate makers stay step ahead of US drug laws as overdose cases rise (the guardian) | http://www.theguardian.com/world/2016/apr/11/synthetic-opiates-drug-laws-w-18-fentanyl</ref>