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MAOI: Difference between revisions
>David Hedlund m m |
>David Hedlund Sort 5-HTP and L-DOPA |
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====By chemicals==== | ====By chemicals==== | ||
*Amino acids, and | *Amino acids, and amino acid metabolism metabolic intermediates | ||
**Amino acids | **Amino acids | ||
***[[5-HTP]] → serotonin | |||
***<small>L</small>-DOPA → dopamine, and epinephrine (adrenaline) | |||
***L-phenylalanine → L-tyrosine, and phenethylamine: Use with caution,<ref>{{cite web |last1=Metcalf |first1=Eric |title=Phenylalanine: Uses and Risks |url=https://www.webmd.com/vitamins-and-supplements/phenylalanine-uses-and-risks |website=WebMD |language=en}}</ref> taking phenylalanine while taking MAOIs may cause a severe increase in blood pressure (hypertensive crisis).<ref>{{cite web |title=Phenylalanine |url=http://slu.adam.com/content.aspx?productid=107&pid=33&gid=000318 |website=slu.adam.com |language=en}}</ref> | ***L-phenylalanine → L-tyrosine, and phenethylamine: Use with caution,<ref>{{cite web |last1=Metcalf |first1=Eric |title=Phenylalanine: Uses and Risks |url=https://www.webmd.com/vitamins-and-supplements/phenylalanine-uses-and-risks |website=WebMD |language=en}}</ref> taking phenylalanine while taking MAOIs may cause a severe increase in blood pressure (hypertensive crisis).<ref>{{cite web |title=Phenylalanine |url=http://slu.adam.com/content.aspx?productid=107&pid=33&gid=000318 |website=slu.adam.com |language=en}}</ref> | ||
***L-tryptophan → 5-HTP, and melatonin: May result in short-term serotonin syndrome.<ref name="Boyer-NEJM">{{cite journal | vauthors = Boyer EW, Shannon M | title = The serotonin syndrome | journal = The New England Journal of Medicine | volume = 352 | issue = 11 | pages = 1112–20 | date = March 2005 | pmid = 15784664 | doi = 10.1056/NEJMra041867 | s2cid = 37959124 | url = https://semanticscholar.org/paper/bd6134bea06b830b36b696ffd7b34b395f6f72ec }}</ref> | ***L-tryptophan → 5-HTP, and melatonin: May result in short-term serotonin syndrome.<ref name="Boyer-NEJM">{{cite journal | vauthors = Boyer EW, Shannon M | title = The serotonin syndrome | journal = The New England Journal of Medicine | volume = 352 | issue = 11 | pages = 1112–20 | date = March 2005 | pmid = 15784664 | doi = 10.1056/NEJMra041867 | s2cid = 37959124 | url = https://semanticscholar.org/paper/bd6134bea06b830b36b696ffd7b34b395f6f72ec }}</ref> | ||
***L-tyrosine → L-DOPA, and tyramine: It is unknown if MAOIs interact with tyrosine, so use with caution.<ref>{{cite web |title=Tyrosine: Benefits, Side Effects and Dosage |url=https://www.healthline.com/nutrition/tyrosine |website=Healthline |language=en |date=1 February 2018}}</ref> | ***L-tyrosine → L-DOPA, and tyramine: It is unknown if MAOIs interact with tyrosine, so use with caution.<ref>{{cite web |title=Tyrosine: Benefits, Side Effects and Dosage |url=https://www.healthline.com/nutrition/tyrosine |website=Healthline |language=en |date=1 February 2018}}</ref> | ||
** | ***Amino acid metabolism metabolic intermediates | ||
* | |||
***[[SAM-e]] → epinephrine (adrenaline) | ***[[SAM-e]] → epinephrine (adrenaline) | ||
*[[Adrenergic]]s | *[[Adrenergic]]s | ||