Talk:N-Methyl-Cyclazodone: Difference between revisions
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'''N-Cyclopropyl-N-Methylpemoline''' (also known as '''N-Methyl-Cyclazodone''' or '''NMC''') is a novel [[psychoactive class::stimulant]] substance of the [[chemical class::4-oxazolidinone]] class. It is structurally related to [[thozalinone]] and [[cyclazodone]]. Similar to [[amphetamine]], the addition of the methyl group on [[cyclazodone]] is thought to increase its potency and duration. The mechanism of action involves promoting the release of [[dopamine]], [[norepinephrine]], and [[serotonin]] in the brain. | '''N-Cyclopropyl-N-Methylpemoline''' (also known as '''N-Methyl-Cyclazodone''' or '''NMC''') is a novel [[psychoactive class::stimulant]] substance of the [[chemical class::4-oxazolidinone]] class. It is structurally related to [[thozalinone]] and [[cyclazodone]]. Similar to [[amphetamine]], the addition of the methyl group on [[cyclazodone]] is thought to increase its potency and duration. The mechanism of action involves promoting the release of [[dopamine]], [[norepinephrine]], and [[serotonin]] in the brain. | ||
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*'''Germany''': Cyclazodone is not a controlled substance under the BtMG (''Narcotics Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/btmg_1981/BJNR106810981.html|title=Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz - BtMG)|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 28, 2019|language=de}}</ref> or the NpSG (''New Psychoactive Substances Act'').<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/BJNR261510016.html|title=Neue-psychoaktive-Stoffe-Gesetz (NpSG)|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 28, 2019|language=de}}</ref> According to §2 AMG (''Medicines Act'') it would fall under the definition of a medicine because it induces pharmacological effect.<ref>{{cite web|url=https://www.gesetze-im-internet.de/amg_1976/__2.html|title=§ 2 AMG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 28, 2019|language=de}}</ref> By a decision of the European Court of Justice, this definition was declared ineffective because it was not compatible with EU law.<ref>{{cite news|url=https://www.lto.de/recht/hintergruende/h/eugh-urteil-c35813-c18114-legal-highs-kein-arzneimittel-strafbar-amg-btmg/|title= Cannabinoide Kräutermischungen vor dem EuGH: Legal Highs bleiben legal|publisher=LTO|author=Prof. Dr. Helmut Pollähne|trans-title=Cannabinoid herbal mixtures at the ECJ: Legal highs stay legal|date=July 11, 2014|access-date=December 28, 2019|language=de}}</ref> Cyclazodone can be considered legal. | *'''Germany''': Cyclazodone is not a controlled substance under the BtMG (''Narcotics Act'')<ref>{{cite web|url=https://www.gesetze-im-internet.de/btmg_1981/BJNR106810981.html|title=Gesetz über den Verkehr mit Betäubungsmitteln (Betäubungsmittelgesetz - BtMG)|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 28, 2019|language=de}}</ref> or the NpSG (''New Psychoactive Substances Act'').<ref>{{cite web|url=https://www.gesetze-im-internet.de/npsg/BJNR261510016.html|title=Neue-psychoaktive-Stoffe-Gesetz (NpSG)|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 28, 2019|language=de}}</ref> According to §2 AMG (''Medicines Act'') it would fall under the definition of a medicine because it induces pharmacological effect.<ref>{{cite web|url=https://www.gesetze-im-internet.de/amg_1976/__2.html|title=§ 2 AMG|publisher=Bundesministerium der Justiz und für Verbraucherschutz|access-date=December 28, 2019|language=de}}</ref> By a decision of the European Court of Justice, this definition was declared ineffective because it was not compatible with EU law.<ref>{{cite news|url=https://www.lto.de/recht/hintergruende/h/eugh-urteil-c35813-c18114-legal-highs-kein-arzneimittel-strafbar-amg-btmg/|title= Cannabinoide Kräutermischungen vor dem EuGH: Legal Highs bleiben legal|publisher=LTO|author=Prof. Dr. Helmut Pollähne|trans-title=Cannabinoid herbal mixtures at the ECJ: Legal highs stay legal|date=July 11, 2014|access-date=December 28, 2019|language=de}}</ref> Cyclazodone can be considered legal. | ||
*'''Switzerland''': Cyclazodone is not controlled under Buchstabe A, B, C and D. It could be considered legal.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref> | *'''Switzerland''': Cyclazodone is not controlled under Buchstabe A, B, C and D. It could be considered legal.<ref>{{cite web|url=https://www.admin.ch/opc/de/classified-compilation/20101220/index.html|title=Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien|publisher=Bundeskanzlei [Federal Chancellery of Switzerland]|access-date=January 1, 2020|language=de}}</ref> | ||
* '''United States''': Cyclazodone being an analogue of [[pemoline]], a Schedule IV controlled substance in the US, may fall under Federal Analogue Act, 21 U.S.C. § 813<ref>https://www.law.cornell.edu/uscode/text/21/813</ref> when intended for human consumption. | *'''United States''': Cyclazodone being an analogue of [[pemoline]], a Schedule IV controlled substance in the US, may fall under Federal Analogue Act, 21 U.S.C. § 813<ref>https://www.law.cornell.edu/uscode/text/21/813</ref> when intended for human consumption. | ||
==See also== | ==See also== | ||
*[[Responsible use]] | *[[Responsible use]] | ||
*[[Research chemicals]] | *[[Research chemicals]] | ||
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==External links== | ==External links== | ||
*[https://en.wikipedia.org/wiki/Cyclazodone Cyclazodone (Wikipedia)] | *[https://en.wikipedia.org/wiki/Cyclazodone Cyclazodone (Wikipedia)] | ||
*[https://isomerdesign.com/PiHKAL/explore.php?id=1434 Cyclazodone (Isomer Design)] | *[https://isomerdesign.com/PiHKAL/explore.php?id=1434 Cyclazodone (Isomer Design)] | ||
==Literature== | ==Literature== | ||
* Segal, D. S., Cox Jr, R. H., Stern, W. C., & Maickel, R. P. (1967). Stimulatory effects of pemoline and cyclopropylpemoline on continuous avoidance behavior: similarity to effects of D-amphetamine. Life Sciences, 6(23), 2567-2572. https://doi.org/10.1016/0024-3205(67)90322-0 | |||
*Segal, D. S., Cox Jr, R. H., Stern, W. C., & Maickel, R. P. (1967). Stimulatory effects of pemoline and cyclopropylpemoline on continuous avoidance behavior: similarity to effects of D-amphetamine. Life Sciences, 6(23), 2567-2572. https://doi.org/10.1016/0024-3205(67)90322-0 | |||
==References== | ==References== |