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[[Subjective effects]] can vary significantly depending on the subclass, but generally include some form of [[geometry|open and closed-eye visuals]], [[time distortion]], [[introspection|enhanced introspection]], [[conceptual thinking]], [[euphoria]], and [[ego loss]]. The so-called classical psychedelics, which consist of [[LSD]], [[psilocybin mushrooms]], [[mescaline]], and [[DMT]] ([[ayahuasca]]) are considered to produce the archetypal psychedelic effects and also have the most established safety profiles. | [[Subjective effects]] can vary significantly depending on the subclass, but generally include some form of [[geometry|open and closed-eye visuals]], [[time distortion]], [[introspection|enhanced introspection]], [[conceptual thinking]], [[euphoria]], and [[ego loss]]. The so-called classical psychedelics, which consist of [[LSD]], [[psilocybin mushrooms]], [[mescaline]], and [[DMT]] ([[ayahuasca]]) are considered to produce the archetypal psychedelic effects and also have the most established safety profiles. | ||
Psychedelics can be divided into three major sub-classes: [[tryptamines]], [[lysergamides]], and [[phenethylamines]]. Psychedelic tryptamines (e.g. [[psilocybin mushrooms|psilocybin]], [[4-AcO-DMT]]) are either based on or derived from [[dimethyltryptamine]] (DMT), lyergamides (e.g. [[LSA]], [[AL-LAD]]) from [[LSD]], and phenethylamines (e.g. [[2C-B]]) | Psychedelics can be divided into three major sub-classes: [[tryptamines]], [[lysergamides]], and [[phenethylamines]]. Psychedelic tryptamines (e.g. [[psilocybin mushrooms|psilocybin]], [[4-AcO-DMT]]) are either based on or derived from [[dimethyltryptamine]] (DMT), lyergamides (e.g. [[LSA]], [[AL-LAD]]) from [[LSD]], and phenethylamines (e.g. [[2C-B]]) from [[mescaline]]. | ||
Unlike other highly prohibited substances, most psychedelics have not been shown to be physiologically toxic and none have been shown to be addictive.<ref name="nicholsPSY" /> However, adverse psychological reactions such as severe [[anxiety]], [[paranoia]], [[delusions]], and [[psychosis]] are always possible, particularly for those predisposed to mental disorders.<ref>{{cite journal|last=Strassmann|first=Rick|title=Adverse reactions to psychedelic drugs. A review of the literature|journal=Journal of Nervous and Mental Disease|volume=172|issue=10|pages=577–595|doi=10.1097/00005053-198410000-00001|pmid=6384428|year=1984|issn=0022-3018|oclc=1754691}}</ref> As a result, it is highly advised to use [[Harm reduction#Hallucinogens|harm reduction practices]] if using these substances. | Unlike other highly prohibited substances, most psychedelics have not been shown to be physiologically toxic and none have been shown to be addictive.<ref name="nicholsPSY" /> However, adverse psychological reactions such as severe [[anxiety]], [[paranoia]], [[delusions]], and [[psychosis]] are always possible, particularly for those predisposed to mental disorders.<ref>{{cite journal|last=Strassmann|first=Rick|title=Adverse reactions to psychedelic drugs. A review of the literature|journal=Journal of Nervous and Mental Disease|volume=172|issue=10|pages=577–595|doi=10.1097/00005053-198410000-00001|pmid=6384428|year=1984|issn=0022-3018|oclc=1754691}}</ref> As a result, it is highly advised to use [[Harm reduction#Hallucinogens|harm reduction practices]] if using these substances. | ||