Psychedelic: Difference between revisions

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[[File:Oversoul by Alex Grey.jpg|300px|thumb|right|''Oversoul'' by '''[http://alexgrey.com/art/paintings/soul/oversoul/ Alex Grey]''' - An example of [[psychedelic]] artwork created by the renowned visionary artist Alex Grey. This image is a representation of an experience report found in the 1901 book [http://en.wikipedia.org/wiki/Cosmic_Consciousness ''Cosmic Consciousness''] ]]

'''Psychedelics''' (also known as '''[[serotonergic]] [[hallucinogens]]''') are a class of [[psychoactive substances]] that produce an altered state of consciousness marked by unusual changes in perception, mood, and cognitive processes.<ref name="nicholsPSY">Nichols, D. E. (2016). Psychedelics. Pharmacological Reviews, 68(2), 264-355. https://doi.org/10.1124/pr.115.011478</ref> While their precise mechanism of action is not known, psychedelic substances are thought to produce their effects by binding to [[serotonin]] ('''5'''-'''h'''ydroxy'''t'''ryptamine or '''5-HT''') [[receptors]] in the central nervous system, particularly the 5-HT<sub>2a</sub> subtype.

'''Psychedelics''' (also known as '''[[serotonergic]] [[hallucinogens]]''') are a class of [[psychoactive substances]] that produce an altered state of consciousness marked by unusual changes in perception, mood, and cognitive processes.<ref name="nicholsPSY">Nichols, D. E. (2016). Psychedelics. Pharmacological Reviews, 68(2), 264-355. https://doi.org/10.1124/pr.115.011478</ref>

Serotonin plays a number of critical roles throughout the human body and is a key [[neurotransmitter]] involved in the functioning and regulation of sensory perception, behavior, mood, cognition and memory.<ref name="nichols5HT">Nichols, D. E., & Nichols, C. D. (2008). Serotonin Receptors. Chemical Reviews, 108(5), 1614-1641. https://doi.org/10.1021/cr078224o</ref>

While the precise mechanism of action is not known, psychedelic substances are thought to produce their effects by binding to [[serotonin]] ('''5'''-'''h'''ydroxy'''t'''ryptamine or '''5-HT''') [[receptors]] in the central nervous system, particularly the 5-HT<sub>2a</sub> subtype. Serotonin plays a number of critical roles throughout the human body and is a key [[neurotransmitter]] involved in the functioning and regulation of sensory perception, behavior, mood, cognition and memory.<ref name="nichols5HT">Nichols, D. E., & Nichols, C. D. (2008). Serotonin Receptors. Chemical Reviews, 108(5), 1614-1641. https://doi.org/10.1021/cr078224o</ref>

Human usage of psychedelics predates written history, and there is growing evidence that they were employed by early cultures in a variety of sociocultural and ritual contexts.<ref name="nicholsPSY" /> In modern times, psychedelic substances are used for a number of purposes that span from the traditional shamanic forms (such as the use of [[ayahuasca]] in the Amazon jungle, or [[peyote]] among Native Americans) to more modern forms of New Age spiritual, [[transpersonal]], or religious practices.

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 [[File:Oversoul by Alex Grey.jpg|300px|thumb|right|''Oversoul'' by '''[http://alexgrey.com/art/paintings/soul/oversoul/ Alex Grey]''' - An example of [[psychedelic]] artwork created by the renowned visionary artist Alex Grey. This image is a representation of an experience report found in the 1901 book [http://en.wikipedia.org/wiki/Cosmic_Consciousness ''Cosmic Consciousness''] ]]
-'''Psychedelics''' (also known as '''[[serotonergic]] [[hallucinogens]]''') are a class of [[psychoactive substances]] that produce an altered state of consciousness marked by unusual changes in perception, mood, and cognitive processes.<ref name="nicholsPSY">Nichols, D. E. (2016). Psychedelics. Pharmacological Reviews, 68(2), 264-355. https://doi.org/10.1124/pr.115.011478</ref> While their precise mechanism of action is not known, psychedelic substances are thought to produce their effects by binding to [[serotonin]] ('''5'''-'''h'''ydroxy'''t'''ryptamine or '''5-HT''') [[receptors]] in the central nervous system, particularly the 5-HT<sub>2a</sub> subtype.
+'''Psychedelics''' (also known as '''[[serotonergic]] [[hallucinogens]]''') are a class of [[psychoactive substances]] that produce an altered state of consciousness marked by unusual changes in perception, mood, and cognitive processes.<ref name="nicholsPSY">Nichols, D. E. (2016). Psychedelics. Pharmacological Reviews, 68(2), 264-355. https://doi.org/10.1124/pr.115.011478</ref>
-Serotonin plays a number of critical roles throughout the human body and is a key [[neurotransmitter]] involved in the functioning and regulation of sensory perception, behavior, mood, cognition and memory.<ref name="nichols5HT">Nichols, D. E., & Nichols, C. D. (2008). Serotonin Receptors. Chemical Reviews, 108(5), 1614-1641. https://doi.org/10.1021/cr078224o</ref>
+While the precise mechanism of action is not known, psychedelic substances are thought to produce their effects by binding to [[serotonin]] ('''5'''-'''h'''ydroxy'''t'''ryptamine or '''5-HT''') [[receptors]] in the central nervous system, particularly the 5-HT<sub>2a</sub> subtype. Serotonin plays a number of critical roles throughout the human body and is a key [[neurotransmitter]] involved in the functioning and regulation of sensory perception, behavior, mood, cognition and memory.<ref name="nichols5HT">Nichols, D. E., & Nichols, C. D. (2008). Serotonin Receptors. Chemical Reviews, 108(5), 1614-1641. https://doi.org/10.1021/cr078224o</ref>
 Human usage of psychedelics predates written history, and there is growing evidence that they were employed by early cultures in a variety of sociocultural and ritual contexts.<ref name="nicholsPSY" /> In modern times, psychedelic substances are used for a number of purposes that span from the traditional shamanic forms (such as the use of [[ayahuasca]] in the Amazon jungle, or [[peyote]] among Native Americans) to more modern forms of New Age spiritual, [[transpersonal]], or religious practices.