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| Total harmala alkaloids were at least 5.9% of dried weight, in one study.<ref name=partial/> | | Total harmala alkaloids were at least 5.9% of dried weight, in one study.<ref name=partial/> |
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| {| class="wikitable sortable" style="text-align: center" | | {{Peganum harmala alkaloids}} |
| |-
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| ! Alkaloid
| |
| ! Content
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| ! Type
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| |-
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| ! [[Desoxypeganine]]<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841998/</ref>
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| | MAO-A<ref>{{cite journal |last1=Algorta |first1=J |last2=Pena |first2=MA |last3=Maraschiello |first3=C |last4=Alvarez-González |first4=A |last5=Maruhn |first5=D |last6=Windisch |first6=M |last7=Mucke |first7=HA |title=Phase I clinical trial with desoxypeganine, a new cholinesterase and selective MAO-A inhibitor: tolerance and pharmacokinetics study of escalating single oral doses. |journal=Methods and findings in experimental and clinical pharmacology |date=March 2008 |volume=30 |issue=2 |pages=141-7 |doi=10.1358/mf.2008.30.2.1159649 |pmid=18560630}}</ref>
| |
| |-
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| ! [[Harmalicidine]]<ref>{{cite journal |last1=Lamchouri |first1=F |last2=Zemzami |first2=M |last3=Jossang |first3=A |last4=Abdellatif |first4=A |last5=Israili |first5=ZH |last6=Lyoussi |first6=B |title=Cytotoxicity of alkaloids isolated from Peganum harmala seeds. |journal=Pakistan journal of pharmaceutical sciences |date=July 2013 |volume=26 |issue=4 |pages=699-706 |pmid=23811445}}</ref>
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| |-
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| ! [[Harmaline]] (harmidine)
| |
| | 0.25%<ref name=partial/>–0.79%<ref name=chroma/>–5.6%<ref name=new1/>
| |
| | [[Reversible inhibitor of monoamine oxidase A]] (RIMA)
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| |-
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| ! [[Harmalol]]
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| | 0.6%<ref name=new1/>–3.90%<ref name=partial/>
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| |-
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| ! [[Harmane]] (harman)
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| | 0.16%<ref name=partial>{{cite journal |vauthors=Hemmateenejad B, Abbaspour A, Maghami H, Miri R, Panjehshahin MR |title=Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts |journal=Anal. Chim. Acta |volume=575 |issue=2 |pages=290–9 |date=August 2006 |pmid=17723604 |doi=10.1016/j.aca.2006.05.093}}</ref>
| |
| | MAO-A and MAO B<ref>{{cite journal |last1=Herraiz |first1=T |last2=Chaparro |first2=C |title=Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee. |journal=Life sciences |date=18 January 2006 |volume=78 |issue=8 |pages=795-802 |doi=10.1016/j.lfs.2005.05.074 |pmid=16139309}}</ref>
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| |-
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| ! [[Harmine]] (banisterine, telepathine)
| |
| | 0.44%<ref name=chroma>{{cite journal |vauthors=Pulpati H, Biradar YS, Rajani M |title=High-performance thin-layer chromatography densitometric method for the quantification of harmine, harmaline, vasicine, and vasicinone in Peganum harmala |journal=J AOAC Int |volume=91 |issue=5 |pages=1179–85 |year=2008 |doi=10.1093/jaoac/91.5.1179 |pmid=18980138|doi-access=free }}</ref>–1.84%<ref name=partial/>–4.3%<ref name=new1>{{cite journal |vauthors=Herraiz T, González D, Ancín-Azpilicueta C, Arán VJ, Guillén H |title=beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO) |journal=Food Chem. Toxicol. |volume=48 |issue=3 |pages=839–45 |date=March 2010 |pmid=20036304 |doi=10.1016/j.fct.2009.12.019}}</ref> – The coatings of the seeds are said to contain large amounts of harmine.<ref name=cdfa/>
| |
| | [[Reversible inhibitor of monoamine oxidase A]] (RIMA)
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| |-
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| ! [[Tetrahydroharmine]] (THH)
| |
| | 0.1%<ref name=new1/>
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| | [[Serotonine reuptake inhibitor]]<ref name="pmid10404423">{{cite journal |last=Callaway |first=James C. |last2=McKenna |first2=Dennis |author-link2=Dennis McKenna |last3=Grob |first3=Charles S. |title=Pharmacokinetics of hoasca alkaloids in healthy humans |journal=[[Journal of Ethnopharmacology]] |volume=65 |issue=3 |pages=243–56 |date=June 1999 |pmid=10404423 |issn=0279-1072 |doi=10.1016/S0378-8741(98)00168-8|display-authors=etal}}</ref>
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| |-
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| ! [[Vasicine]] (peganine)<ref name=nook/>
| |
| | 0.25%<ref name=chroma/>
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| |
| |
| |-
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| ! [[Vasicinone]]<ref name=nook/>
| |
| | 0.0007%<ref name=chroma/>
| |
| |
| |
| |}
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| ==Toxicity and harm potential== | | ==Toxicity and harm potential== |
