Diphenidine: Difference between revisions

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'''Diphenidine''' (also known as DPD, DND, 1,2-DEP, and DPH) is a lesser-known novel [[psychoactive class::dissociative]] substance of the [[chemical class::diarylethylamine]] class that produces [[dissociative]] and [[hallucinogenic]] effects when [[administered]]. It is structurally related to [[methoxphenidine]] and [[ephenidine]].

'''Diphenidine''' (also known as DPD, DND, 1,2-DEP, and DPH) is a lesser-known novel [[psychoactive class::dissociative]] substance of the [[chemical class::diarylethylamine]] class that produces [[dissociative]] and [[hallucinogenic]] effects when [[administered]]. It is structurally related to [[methoxphenidine]] and [[ephenidine]]~~. It is sometimes referred to as DPH in scientific studies despite this name already being in use and widely accepted as meaning [[diphenhydramine]], an unrelated substance~~.

The synthesis of diphenidine was first reported in 1924. Shortly after the 2013 UK [[arylcyclohexylamine]] ban, diphenidine and the related compound [[methoxphenidine]] became available on the grey market. In 2014, there were two cases of diphenidine being sold in combination with synthetic cannabinoids in Japanese herbal incense blends, one of which was implicated in a fatal overdose.

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In 2014, there were two cases of diphenidine being sold in combination with synthetic [[cannabinoids]] in Japanese herbal incense blends. One herbal incense blend was found to contain diphenidine and [[5-fluoro-AB-PINACA]] at concentrations of 289 mg/g and 55.5 mg/g, respectively.<ref>http://link.springer.com/article/10.1007%2Fs11419-014-0240-y | http://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=0346791&KC=&FT=E&locale=en_EP</ref> Another product containing AB-CHMINACA, 5F-AMB, and diphenidine was implicated in a fatal overdose.<ref>Postmortem distribution of AB-CHMINACA, 5-fluoro-AMB, and diphenidine in body fluids and solid tissues in a fatal poisoning case: usefulness of adipose tissue for detection of the drugs in unchanged forms | http://link.springer.com/article/10.1007%2Fs11419-014-0245-6</ref>

===Names===

Diphenidine is sometimes referred to as "DPH" in scientific studies despite this name already being in use and widely accepted as meaning [[diphenhydramine]], an unrelated substance.

==Chemistry==

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 {{SummarySheet}}
 {{SubstanceBox/Diphenidine}}
+'''Diphenidine''' (also known as DPD, DND, 1,2-DEP, and DPH) is a lesser-known novel [[psychoactive class::dissociative]] substance of the [[chemical class::diarylethylamine]] class that produces [[dissociative]] and [[hallucinogenic]] effects when [[administered]]. It is structurally related to [[methoxphenidine]] and [[ephenidine]].
-'''Diphenidine''' (also known as DPD, DND, 1,2-DEP, and DPH) is a lesser-known novel [[psychoactive class::dissociative]] substance of the [[chemical class::diarylethylamine]] class that produces [[dissociative]] and [[hallucinogenic]] effects when [[administered]]. It is structurally related to [[methoxphenidine]] and [[ephenidine]]. It is sometimes referred to as DPH in scientific studies despite this name already being in use and widely accepted as meaning [[diphenhydramine]], an unrelated substance.
 The synthesis of diphenidine was first reported in 1924. Shortly after the 2013 UK [[arylcyclohexylamine]] ban, diphenidine and the related compound [[methoxphenidine]] became available on the grey market. In 2014, there were two cases of diphenidine being sold in combination with synthetic cannabinoids in Japanese herbal incense blends, one of which was implicated in a fatal overdose.
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 In 2014, there were two cases of diphenidine being sold in combination with synthetic [[cannabinoids]] in Japanese herbal incense blends. One herbal incense blend was found to contain diphenidine and [[5-fluoro-AB-PINACA]] at concentrations of 289 mg/g and 55.5 mg/g, respectively.<ref>http://link.springer.com/article/10.1007%2Fs11419-014-0240-y | http://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=0346791&KC=&FT=E&locale=en_EP</ref> Another product containing AB-CHMINACA, 5F-AMB, and diphenidine was implicated in a fatal overdose.<ref>Postmortem distribution of AB-CHMINACA, 5-fluoro-AMB, and diphenidine in body fluids and solid tissues in a fatal poisoning case: usefulness of adipose tissue for detection of the drugs in unchanged forms | http://link.springer.com/article/10.1007%2Fs11419-014-0245-6</ref>
+===Names===
+Diphenidine is sometimes referred to as "DPH" in scientific studies despite this name already being in use and widely accepted as meaning [[diphenhydramine]], an unrelated substance.
 ==Chemistry==