4-FA: Difference between revisions - PsychonautWiki Archive

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'''4-Fluoroamphetamine''' (also known as '''4-FA''', '''4-FMP''', '''para-Fluoroamphetamine''', '''PAL-303''' and colloquially as '''Flux''') is a novel synthetic [[chemical class::amphetamine|~~substituted~~ amphetamine]] compound that produces a unique progressive mixture of [[psychoactive class::entactogen|entactogenic]] and [[psychoactive class::stimulant]] effects when [[Routes of administration|administered]]. It is part of a series of fluorinated amphetamine analog that initially included such compounds as [[2-FA]], [[2-FMA]], and [[3-FA]].<ref>Quednow, B., Girreser, U., Junge, T., & Ro, P. (2005). Isomeric Fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs), 148, 143–156. https://doi.org/10.1016/j.forsciint.2004.05.003</ref>

'''4-Fluoroamphetamine''' (also known as '''4-FA''', '''4-FMP''', '''para-Fluoroamphetamine''', '''PAL-303''' and colloquially as '''Flux''') is a novel synthetic [[chemical class::Substituted amphetamine|amphetamine]] compound that produces a unique progressive mixture of [[psychoactive class::entactogen|entactogenic]] and [[psychoactive class::stimulant]] effects when [[Routes of administration|administered]]. It is part of a series of fluorinated amphetamine analog that initially included such compounds as [[2-FA]], [[2-FMA]], and [[3-FA]].<ref>Quednow, B., Girreser, U., Junge, T., & Ro, P. (2005). Isomeric Fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs), 148, 143–156. https://doi.org/10.1016/j.forsciint.2004.05.003</ref>

Anecdotal reports have described the subjective effects of [[4-FA]] as having a moderate [[MDMA|MDMA-like]] [[entactogenic]] onset for the initial few hours of the experience that then gradually transitions into traditional [[amphetamine|amphetamine-type]] [[stimulation]] (for a total duration of around 6 to 8 hours) with residual effects that can last a few hours afterward.{{citation needed}}

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==Chemistry==

4-Fluoroamphetamine (4-FA) is a synthetic molecule of the [[amphetamine]] family. Molecules of the amphetamine class contain a [[phenethylamine]] core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. Amphetamines are alpha-methylated phenethylamines. 4-fluoroamphetamine contains a fluorine atom at R4 of its phenyl ring and is a fluorinated analogue of amphetamine.

4-Fluoroamphetamine (4-FA) is a synthetic molecule of the [[Substituted amphetamine|amphetamine]] family. Molecules of the amphetamine class contain a [[phenethylamine]] core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. Amphetamines are alpha-methylated phenethylamines. 4-fluoroamphetamine contains a fluorine atom at R4 of its phenyl ring and is a fluorinated analogue of amphetamine.

[[File:samphetamine.png|thumb|right|240px|thumb|right||Substitutive structure of an amphetamine molecule]]

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 {{SubstanceBox/4-FA}}
-'''4-Fluoroamphetamine''' (also known as '''4-FA''', '''4-FMP''', '''para-Fluoroamphetamine''', '''PAL-303''' and colloquially as '''Flux''') is a novel synthetic [[chemical class::amphetamine|substituted amphetamine]] compound that produces a unique progressive mixture of [[psychoactive class::entactogen|entactogenic]] and [[psychoactive class::stimulant]] effects when [[Routes of administration|administered]]. It is part of a series of fluorinated amphetamine analog that initially included such compounds as [[2-FA]], [[2-FMA]], and [[3-FA]].<ref>Quednow, B., Girreser, U., Junge, T., & Ro, P. (2005). Isomeric Fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs), 148, 143–156. https://doi.org/10.1016/j.forsciint.2004.05.003</ref>
+'''4-Fluoroamphetamine''' (also known as '''4-FA''', '''4-FMP''', '''para-Fluoroamphetamine''', '''PAL-303''' and colloquially as '''Flux''') is a novel synthetic [[chemical class::Substituted amphetamine|amphetamine]] compound that produces a unique progressive mixture of [[psychoactive class::entactogen|entactogenic]] and [[psychoactive class::stimulant]] effects when [[Routes of administration|administered]]. It is part of a series of fluorinated amphetamine analog that initially included such compounds as [[2-FA]], [[2-FMA]], and [[3-FA]].<ref>Quednow, B., Girreser, U., Junge, T., & Ro, P. (2005). Isomeric Fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs), 148, 143–156. https://doi.org/10.1016/j.forsciint.2004.05.003</ref>
 Anecdotal reports have described the subjective effects of [[4-FA]] as having a moderate [[MDMA|MDMA-like]] [[entactogenic]] onset for the initial few hours of the experience that then gradually transitions into traditional [[amphetamine|amphetamine-type]] [[stimulation]] (for a total duration of around 6 to 8 hours) with residual effects that can last a few hours afterward.{{citation needed}}
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 ==Chemistry==
--Fluoroamphetamine (4-FA) is a synthetic molecule of the [[amphetamine]] family.  Molecules of the amphetamine class contain a [[phenethylamine]] core featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group through an ethyl chain with an additional methyl substitution at R<sub>α</sub>. Amphetamines are alpha-methylated phenethylamines. 4-fluoroamphetamine contains a fluorine atom at R<sub>4</sub> of its phenyl ring and is a fluorinated analogue of amphetamine.
+-Fluoroamphetamine (4-FA) is a synthetic molecule of the [[Substituted amphetamine|amphetamine]] family.  Molecules of the amphetamine class contain a [[phenethylamine]] core featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group through an ethyl chain with an additional methyl substitution at R<sub>α</sub>. Amphetamines are alpha-methylated phenethylamines. 4-fluoroamphetamine contains a fluorine atom at R<sub>4</sub> of its phenyl ring and is a fluorinated analogue of amphetamine.
 [[File:samphetamine.png|thumb|right|240px|thumb|right||Substitutive structure of an amphetamine molecule]]