Talk:Bromazolam: Difference between revisions

Line 6:

Page 8 of their reports on ROA's and dosage seemed most particularly helpful.

Light dosage range is reported to be: (0,5mg-1mg) Common dosage range is reported to be: (1mg-2mg) Strong/heavy dosage range is reported to be:(2mg-4mg)

Light dosage range is reported to be: (0,5mg-1mg) Common dosage range is reported to be: (1mg-2mg) Strong/heavy dosage range is reported to be:(2mg-4mg+)

"Onset of effects after oral use is estimated to be 15–45 min, and the duration of action is 5–8 h." - WHO Critical Review findings <ref>[https://cdn.who.int/media/docs/default-source/controlled-substances/45th-ecdd/bromazolam_draft.pdf?sfvrsn=f1bc761e_1https://cdn.who.int/media/docs/default-source/controlled-substances/45th-ecdd/bromazolam_draft.pdf?sfvrsn=f1bc761e_1 WHO Critical Review Report: Bromazolam(2022)]</ref>

''Bromazolam''' (also known as '''Brom''', '''Bromaz''', or '''XLI-268''') is a [[psychoactive class::depressant]] substance of the [[Chemical class::benzodiazepine]] class - more specifically it is a [[Triazolobenzodiazepine]] (TBZD). Its characteristic effects include [[anxiety suppression]], [[sedation]], [[disinhibition]], and [[muscle relaxation]]. <s>It is currently [[Unscheduled]] in most parts of the world, and hence it is commonly sold as a [[Research chemicals|Research chemical]]</s>. Bromazolam was virtually as unregulated as even the most obscure research chemicals known to man until early 2023 the United States DEA and DOJ working in tandem added Flubramzolam, Etizolam, and several other designer benzodiazepines into Emergency Schedule I. ~~Althought bromazolam~~ itself curiously was not one of the substances added, the fact that ~~flubromazolam~~ and many other very similar drugs are in Emergency Schedule I at the Federal Level. meaning that, as a Schedule I or II illegal narcotic, even ~~bromazolam~~ itself is now illegal federally because Schedule I and II narcotics are covered by the Federal Analogues Act.

''Bromazolam''' (also known as '''Brom''', '''Bromaz''', or '''XLI-268''') is a [[psychoactive class::depressant]] substance of the [[Chemical class::benzodiazepine]] class - more specifically it is a [[Triazolobenzodiazepine]] (TBZD). Its characteristic effects include [[anxiety suppression]], [[sedation]], [[disinhibition]], and [[muscle relaxation]]. <s>It is currently [[Unscheduled]] in most parts of the world, and hence it is commonly sold as a [[Research chemicals|Research chemical]]</s>. Bromazolam was virtually as unregulated as even the most obscure research chemicals known to man until early 2023 the United States DEA and DOJ working in tandem added Flubramzolam, Etizolam, and several other designer benzodiazepines into Emergency Schedule I. Although Bromazolam itself curiously was not one of the substances added, the fact that Flubromazolam and many other very similar drugs are in Emergency Schedule I at the Federal Level. meaning that, as a Schedule I or II illegal narcotic, even Bromazolam itself is now illegal federally because Schedule I and II narcotics are covered by the Federal Analogues Act.

Like other [[benzodiazepines]], [[Bromazolam]] binds to specific sites on the [[gamma-amino-butyric acid|GABA<sub>A</sub>]] receptor.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303399/</ref> Since it is not available by prescription and is sold online on [[clearnet]] and [[darknet]] vendors - it is commonly used to self-medicate or for recreational purposes.

Line 23:

==History and culture==

[[Bromazolam]] (XLI-268) is a [[Triazolobenzodiazepine]] (TBZD) which was first synthesized in 1976,and was developed as a canidate medication, bur was never approved for use, and was never marketed.<ref>Manchester KR, Lomas EC, Waters L, Dempsey FC, Maskell PD (January 2018). "The emergence wiener of new psychoactive substance (NPS) benzodiazepines: A review". Drug Testing and Analysis. 10 (1): 37–53. doi:10.1002/dta.2211. <nowiki>PMID 28471096</nowiki>. </ref> [[Bromazolam]] was first found definitively in Sweden in 2016 by the EMCDDA. Since then, the compound has been detected in products or in biological samples in nine countries: Australia, Austria, China, Finland, Germany, India, and Sweden, the United Kingdom (Wales) and in the USA. [[Bromazolam]] is not under international control.

[[Bromazolam]] (XLI-268) is a [[Triazolobenzodiazepine]] (TBZD) which was first synthesized in 1976 by Hofman LaRoche, and was developed as a canidate medication, bur was never approved for use, and was never marketed.<ref>Manchester KR, Lomas EC, Waters L, Dempsey FC, Maskell PD (January 2018). "The emergence wiener of new psychoactive substance (NPS) benzodiazepines: A review". Drug Testing and Analysis. 10 (1): 37–53. doi:10.1002/dta.2211. <nowiki>PMID 28471096</nowiki>. </ref> [[Bromazolam]] was first found definitively in Sweden in 2016 by the EMCDDA. Since then, the compound has been detected in products or in biological samples in nine countries: Australia, Austria, China, Finland, Germany, India, and Sweden, the United Kingdom (Wales) and in the USA. [[Bromazolam]] is not under international control.

Bromazolam seems to be commonly sold as blue Diazepam pills <ref>https://www.wedinos.org/sample-results</ref> in the UK.

@@ Line 6: / Line 6: @@
 Page 8 of their reports on ROA's and dosage seemed most particularly helpful.
-Light dosage range is reported to be: (0,5mg-1mg) Common dosage range is reported to be: (1mg-2mg) Strong/heavy dosage range is reported to be:(2mg-4mg)
+Light dosage range is reported to be: (0,5mg-1mg) Common dosage range is reported to be: (1mg-2mg) Strong/heavy dosage range is reported to be:(2mg-4mg+)
 "Onset of effects after oral use is estimated to be 15–45 min, and the duration of action is 5–8 h." - WHO Critical Review findings <ref>[https://cdn.who.int/media/docs/default-source/controlled-substances/45th-ecdd/bromazolam_draft.pdf?sfvrsn=f1bc761e_1https://cdn.who.int/media/docs/default-source/controlled-substances/45th-ecdd/bromazolam_draft.pdf?sfvrsn=f1bc761e_1 WHO Critical Review Report: Bromazolam(2022)]</ref>
-''Bromazolam''' (also known as '''Brom''', '''Bromaz''', or '''XLI-268''') is a [[psychoactive class::depressant]] substance of the [[Chemical class::benzodiazepine]] class - more specifically it is a [[Triazolobenzodiazepine]] (TBZD). Its characteristic effects include [[anxiety suppression]], [[sedation]], [[disinhibition]], and [[muscle relaxation]]. <s>It is currently [[Unscheduled]] in most parts of the world, and hence it is commonly sold as a [[Research chemicals|Research chemical]]</s>. Bromazolam was virtually as unregulated as even the most obscure research chemicals known to man until early 2023 the United States DEA and DOJ working in tandem added Flubramzolam, Etizolam, and several other designer benzodiazepines into Emergency Schedule I. Althought bromazolam itself curiously was not one of the substances added, the fact that flubromazolam and many other very similar drugs are in Emergency Schedule I at the Federal Level. meaning that, as a Schedule I or II illegal narcotic, even bromazolam itself is now illegal federally because Schedule I and II narcotics are covered by the Federal Analogues Act.
+''Bromazolam''' (also known as '''Brom''', '''Bromaz''', or '''XLI-268''') is a [[psychoactive class::depressant]] substance of the [[Chemical class::benzodiazepine]] class - more specifically it is a [[Triazolobenzodiazepine]] (TBZD). Its characteristic effects include [[anxiety suppression]], [[sedation]], [[disinhibition]], and [[muscle relaxation]]. <s>It is currently [[Unscheduled]] in most parts of the world, and hence it is commonly sold as a [[Research chemicals|Research chemical]]</s>. Bromazolam was virtually as unregulated as even the most obscure research chemicals known to man until early 2023 the United States DEA and DOJ working in tandem added Flubramzolam, Etizolam, and several other designer benzodiazepines into Emergency Schedule I. Although Bromazolam itself curiously was not one of the substances added, the fact that Flubromazolam and many other very similar drugs are in Emergency Schedule I at the Federal Level. meaning that, as a Schedule I or II illegal narcotic, even Bromazolam itself is now illegal federally because Schedule I and II narcotics are covered by the Federal Analogues Act.
 Like other [[benzodiazepines]], [[Bromazolam]] binds to specific sites on the [[gamma-amino-butyric acid|GABA<sub>A</sub>]] receptor.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303399/</ref> Since it is not available by prescription and is sold online on [[clearnet]] and [[darknet]] vendors - it is commonly used to self-medicate or for recreational purposes.
@@ Line 23: / Line 23: @@
 ==History and culture==
 {{historyStub}}
-[[Bromazolam]] (XLI-268) is a [[Triazolobenzodiazepine]] (TBZD) which was first synthesized in 1976,and was developed as a canidate medication, bur was never approved for use, and was never marketed.<ref>Manchester KR, Lomas EC, Waters L, Dempsey FC, Maskell PD (January 2018). "The emergence wiener of new psychoactive substance (NPS) benzodiazepines: A review". Drug Testing and Analysis. 10 (1): 37–53. doi:10.1002/dta.2211. <nowiki>PMID 28471096</nowiki>. </ref> [[Bromazolam]] was first found definitively in Sweden in 2016 by the EMCDDA. Since then, the compound has been detected in products or in biological samples in nine countries: Australia, Austria, China, Finland, Germany, India, and Sweden, the United Kingdom (Wales) and in the USA. [[Bromazolam]] is not under international control.
+[[Bromazolam]] (XLI-268) is a [[Triazolobenzodiazepine]] (TBZD) which was first synthesized in 1976 by Hofman LaRoche, and was developed as a canidate medication, bur was never approved for use, and was never marketed.<ref>Manchester KR, Lomas EC, Waters L, Dempsey FC, Maskell PD (January 2018). "The emergence wiener of new psychoactive substance (NPS) benzodiazepines: A review". Drug Testing and Analysis. 10 (1): 37–53. doi:10.1002/dta.2211. <nowiki>PMID 28471096</nowiki>. </ref> [[Bromazolam]] was first found definitively in Sweden in 2016 by the EMCDDA. Since then, the compound has been detected in products or in biological samples in nine countries: Australia, Austria, China, Finland, Germany, India, and Sweden, the United Kingdom (Wales) and in the USA. [[Bromazolam]] is not under international control.
 Bromazolam seems to be commonly sold as blue Diazepam pills <ref>https://www.wedinos.org/sample-results</ref> in the UK.