1cP-LSD: Difference between revisions - PsychonautWiki Archive

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'''1-Cyclopropionyl-''d''-lysergic acid diethylamide''' (also known as '''1cP-LSD''') is a novel semisynthetic [[Psychoactive class::psychedelic]] substance of the [[Chemical class::lysergamide]] class.

1cP-LSD is closely related to [[1P-LSD]] and [[LSD]]. It is reported to produce similar to identical effects.

Little is known about the pharmacology of 1cP-LSD, ~~but~~ it ~~likely~~ produces its psychedelic effects by acting on [[serotonin]] [[receptors]] in the brain.

Little is known about the pharmacology of 1cP-LSD, it produces its psychedelic effects by acting on [[serotonin]] [[receptors]] in the brain.<ref name="Brandt2020">{{cite journal|title=Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1‐cyclopropanoyl‐d‐lysergic acid diethylamide (1CP‐LSD)|first1=Simon D.|last1=Brandt|first2=Pierce V.|last2=Kavanagh|first3=Folker|last3=Westphal|first4=Alexander|last4=Stratford|first5=Anna U.|last5=Odland|first6=Adam K.|last6=Klein|first7=Geraldine|last7=Dowling|first8=Nicola M.|last8=Dempster|first9=Jason|last9=Wallach|first10=Torsten|last10=Passie|first11=Adam L.|last11=Halberstadt|date=March 16, 2020|doi=10.1002/dta.2789|volume=12|issue=6|journal=Drug Testing and Analysis|pages=812-826|eissn=1942-7611|issn=1942-7603|oclc=231680670}}</ref>

~~The similarities in chemical structure between 1cP-~~LSD ~~and~~ LSD ~~predict a similar effect profile~~.

Incubation of 1CP‐LSD with human serum led to the formation of LSD, indicating that it may act as a [[prodrug]] for LSD.<ref name="Brandt2020"></ref>

Characteristic effects include [[geometry|geometric visual hallucinations]], [[time distortion]], [[introspection|enhanced introspection]], and [[ego loss]].

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==History and culture==

1cP-LSD first appeared on the online research chemical market in July 2019.<ref>1cP-LSD (Google Trends) | https://trends.google.com/trends/explore?date=all&q=1cp-lsd</ref>

1cP-LSD first appeared on the online research chemical market in July 2019.<ref>{{cite web|title=1cP-LSD|publisher=Google Trends|access-date=July 14, 2020|url=https://trends.google.com/trends/explore?date=all&q=1cp-lsd}}</ref>

==Chemistry==

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 {{SummarySheet}}
 {{SubstanceBox/1cP-LSD}}
 '''1-Cyclopropionyl-''d''-lysergic acid diethylamide''' (also known as '''1cP-LSD''') is a novel semisynthetic [[Psychoactive class::psychedelic]] substance of the [[Chemical class::lysergamide]] class.
 cP-LSD is closely related to [[1P-LSD]] and [[LSD]]. It is reported to produce similar to identical effects.
-Little is known about the pharmacology of 1cP-LSD, but it likely produces its psychedelic effects by acting on [[serotonin]] [[receptors]] in the brain.
+Little is known about the pharmacology of 1cP-LSD, it produces its psychedelic effects by acting on [[serotonin]] [[receptors]] in the brain.<ref name="Brandt2020">{{cite journal|title=Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1‐cyclopropanoyl‐d‐lysergic acid diethylamide (1CP‐LSD)|first1=Simon D.|last1=Brandt|first2=Pierce V.|last2=Kavanagh|first3=Folker|last3=Westphal|first4=Alexander|last4=Stratford|first5=Anna U.|last5=Odland|first6=Adam K.|last6=Klein|first7=Geraldine|last7=Dowling|first8=Nicola M.|last8=Dempster|first9=Jason|last9=Wallach|first10=Torsten|last10=Passie|first11=Adam L.|last11=Halberstadt|date=March 16, 2020|doi=10.1002/dta.2789|volume=12|issue=6|journal=Drug Testing and Analysis|pages=812-826|eissn=1942-7611|issn=1942-7603|oclc=231680670}}</ref>
-The similarities in chemical structure between 1cP-LSD and LSD predict a similar effect profile.
+Incubation of 1CP‐LSD with human serum led to the formation of LSD, indicating that it may act as a [[prodrug]] for LSD.<ref name="Brandt2020"></ref>
 Characteristic effects include [[geometry|geometric visual hallucinations]], [[time distortion]], [[introspection|enhanced introspection]], and [[ego loss]].
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 ==History and culture==
 {{historyStub}}
-cP-LSD first appeared on the online research chemical market in July 2019.<ref>1cP-LSD (Google Trends) | https://trends.google.com/trends/explore?date=all&q=1cp-lsd</ref>
+cP-LSD first appeared on the online research chemical market in July 2019.<ref>{{cite web|title=1cP-LSD|publisher=Google Trends|access-date=July 14, 2020|url=https://trends.google.com/trends/explore?date=all&q=1cp-lsd}}</ref>
 ==Chemistry==