Clonidine: Difference between revisions

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*'''[[Effect::Sedation]]''' - Clonidine can produce a strong sedative effect, which has been compared to that of [[benzodiazepines]]. Users can become very tired and sleep through prompts to awake.

*'''[[Effect::Decreased heart rate]]'''<ref>Anderson, R. J., Hart, G. R., Crumpler, C. P., & Lerman, M. J. (1981). Clonidine overdose: report of six cases and review of the literature. Annals of emergency medicine, 10(2), 107-112. | https://www.ncbi.nlm.nih.gov/pubmed/7013572</ref> - In normal use as well as overdose, heartrate is lowered and is directly affected by how much is taken.

*'''[[Effect::Decreased blood pressure]]''' - Clonidine's sympatholytic effects quickly and effectively ~~lowers~~ blood pressure.<ref>Mitchell A, Bührmann S, Opazo Saez A, Rushentsova U, Schäfers RF, Philipp T, et al. Clonidine lowers blood pressure by reducing vascular resistance and cardiac output in young, healthy males. Cardiovasc Drugs Ther 2005;19:49–55. pmid:15883756</ref> Users should take care to avoid standing up too quickly to avoid an overwhelming light-headedness and possible fainting spell.

*'''[[Effect::Decreased blood pressure]]''' - Clonidine's sympatholytic effects quickly and effectively lower blood pressure.<ref>Mitchell A, Bührmann S, Opazo Saez A, Rushentsova U, Schäfers RF, Philipp T, et al. Clonidine lowers blood pressure by reducing vascular resistance and cardiac output in young, healthy males. Cardiovasc Drugs Ther 2005;19:49–55. pmid:15883756</ref> Users should take care to avoid standing up too quickly to avoid an overwhelming light-headedness and possible fainting spell.

*'''[[Effect::Abnormal heartbeat]]''' - This effect has a low likelihood. Caution should be taken if clonidine is taken with other substances that affect heartbeat. Intense physical activity should be avoided while on this substance.

*'''[[Effect::Dry mouth]]'''

@@ Line 77: / Line 77: @@
 *'''[[Effect::Sedation]]''' - Clonidine can produce a strong sedative effect, which has been compared to that of [[benzodiazepines]]. Users can become very tired and sleep through prompts to awake.
 *'''[[Effect::Decreased heart rate]]'''<ref>Anderson, R. J., Hart, G. R., Crumpler, C. P., & Lerman, M. J. (1981). Clonidine overdose: report of six cases and review of the literature. Annals of emergency medicine, 10(2), 107-112. | https://www.ncbi.nlm.nih.gov/pubmed/7013572</ref> - In normal use as well as overdose, heartrate is lowered and is directly affected by how much is taken.
-*'''[[Effect::Decreased blood pressure]]''' - Clonidine's sympatholytic effects quickly and effectively lowers blood pressure.<ref>Mitchell A, Bührmann S, Opazo Saez A, Rushentsova U, Schäfers RF, Philipp T, et al. Clonidine lowers blood pressure by reducing vascular resistance and cardiac output in young, healthy males. Cardiovasc Drugs Ther 2005;19:49–55. pmid:15883756</ref> Users should take care to avoid standing up too quickly to avoid an overwhelming light-headedness and possible fainting spell.
+*'''[[Effect::Decreased blood pressure]]''' - Clonidine's sympatholytic effects quickly and effectively lower blood pressure.<ref>Mitchell A, Bührmann S, Opazo Saez A, Rushentsova U, Schäfers RF, Philipp T, et al. Clonidine lowers blood pressure by reducing vascular resistance and cardiac output in young, healthy males. Cardiovasc Drugs Ther 2005;19:49–55. pmid:15883756</ref> Users should take care to avoid standing up too quickly to avoid an overwhelming light-headedness and possible fainting spell.
 *'''[[Effect::Abnormal heartbeat]]''' - This effect has a low likelihood. Caution should be taken if clonidine is taken with other substances that affect heartbeat. Intense physical activity should be avoided while on this substance.
 *'''[[Effect::Dry mouth]]'''