AB-FUBINACA: Difference between revisions

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'''AB-FUBINACA''' ('''N-[(1S)-1-(Aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide''') is a drug that acts as a potent agonist for the [[Psychoactive class::cannabinoid]] [[receptor]]s which produces subjective effects somewhat similar to that of [[cannabis]]. It was originally developed by Pfizer in 2009 as an [[analgesic]] medication,<ref>The cannabinoid receptors (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/12432948</ref> but was never pursued for human use. Subsequently in 2012, this compound was discovered as an ingredient in synthetic cannabis blends in Japan<ref>Uchiyama, N.; Matsuda, S.; Wakana, D.; Kikura-Hanajiri, R.; Goda, Y. (2012). "New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as [[designer drug]]s in illegal products".</ref> along with a related compound [[AB-PINACA]] which had not previously been reported.
'''AB-FUBINACA''' ('''N-[(1S)-1-(Aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide''') is a drug that acts as a potent agonist for the [[Psychoactive class::cannabinoid]] [[receptor]]s which produces subjective effects somewhat similar to that of [[cannabis]]. It was originally developed by Pfizer in 2009 as an [[analgesic]] medication,<ref>The cannabinoid receptors (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/12432948</ref> but was never pursued for human use. Subsequently in 2012, this compound was discovered as an ingredient in synthetic cannabis blends in Japan<ref>Uchiyama, N.; Matsuda, S.; Wakana, D.; Kikura-Hanajiri, R.; Goda, Y. (2012). "New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as [[designer drug]]s in illegal products".</ref> along with a related compound [[AB-PINACA]] which had not previously been reported.