Talk:Olanzapine: Difference between revisions

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[[File:Apotex-manufactured olanzapine 5 mg ODT.jpg|400px|thumbnail|right|A five milligram tablet of olanzapine manufactured by Apotex. This tablet is designed to dissolve in the mouth and be absorbed through the blood vessels inside of the mouth.]]

'''Olanzapine''', first branded as '''Zyprexa''', is a widely-used [[psychoactive class::antipsychotic]] substance of the [[chemical class::thienobenzodiazepine]] chemical class. It produces sedating and neuroleptic effects when administered. Olanzapine is known to cause weight gain and help induce Diabetes mellitus type 2 more frequently than other antipsychotics. On the other hand, it has less of a chance of producing tardive dyskinesia or an extrapyramidal reaction and also seems to treat schizophrenia very effectively.<ref>Leucht, S., Cipriani, A., Spineli, L., Mavridis, D., Örey, D., Richter, F., ... & Kissling, W. (2013). Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. The Lancet, 382(9896), 951-962.</ref> Olanzapine can be given [[Routes of Administration#Oral|by mouth]] and can also be [[Routes of Administration#Intramuscular|injected into a muscle.]] Telenzepine is another agent that shares the thienobenzodiazepine core structure.

:(doses:

:Light: 2.5 mg

:Medium: 5 to 7.5 mg

:Heavy: 10 mg

:Strong: 10 mg +)

==Subjective effects==

===Physical effects===

*'''[[Appetite stimulation|Hunger]]''' - This often happens over a course of treatment and not with one use.

*'''[[Sedation]]'''

*'''[[Salivation]]'''

===Cognitive effects===

*'''[[Anxiety suppression]]''' - This is mediated by olanzapine's antidopaminergic, antiadrenergic, and serotonergic action rather than GABA-related activity.

@@ Line 3: / Line 3: @@
 [[File:Apotex-manufactured olanzapine 5 mg ODT.jpg|400px|thumbnail|right|A five milligram tablet of olanzapine manufactured by Apotex. This tablet is designed to dissolve in the mouth and be absorbed through the blood vessels inside of the mouth.]]
 '''Olanzapine''', first branded as '''Zyprexa''', is a widely-used [[psychoactive class::antipsychotic]] substance of the [[chemical class::thienobenzodiazepine]] chemical class. It produces sedating and neuroleptic effects when administered. Olanzapine is known to cause weight gain and help induce Diabetes mellitus type 2 more frequently than other antipsychotics. On the other hand, it has less of a chance of producing tardive dyskinesia or an extrapyramidal reaction and also seems to treat schizophrenia very effectively.<ref>Leucht, S., Cipriani, A., Spineli, L., Mavridis, D., Örey, D., Richter, F., ... & Kissling, W. (2013). Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. The Lancet, 382(9896), 951-962.</ref> Olanzapine can be given [[Routes of Administration#Oral|by mouth]] and can also be [[Routes of Administration#Intramuscular|injected into a muscle.]] Telenzepine is another agent that shares the thienobenzodiazepine core structure.
+:(doses:
+:Light: 2.5 mg
+:Medium: 5 to 7.5 mg
+:Heavy: 10 mg
+:Strong: 10 mg +)
+==Subjective effects==
+===Physical effects===
+*'''[[Appetite stimulation|Hunger]]''' - This often happens over a course of treatment and not with one use.
+*'''[[Sedation]]'''
+*'''[[Salivation]]'''
+===Cognitive effects===
+*'''[[Anxiety suppression]]''' - This is mediated by olanzapine's antidopaminergic, antiadrenergic, and serotonergic action rather than GABA-related activity.