Talk:Clozapine: Difference between revisions

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{{decree|type=style|message=Neither the link format follows our usual format, nor does a summary or a verified substance box exist. Please help by contributing so that this article can be published.}}

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==Pharmacology==

~~Cloazapine~~ is classified as and was the first atypical antipsychotic agent. It binds to several types of central nervous system receptors and displays a unique pharmacological profile. It is a [[serotonin]] antagonist, with strong binding to the 5-HT2A and 5-HT2C receptor subtypes.

Clozapine is classified as and was the first atypical antipsychotic agent. It binds to several types of central nervous system receptors and displays a unique pharmacological profile. It is a [[serotonin]] antagonist, with strong binding to the 5-HT2A and 5-HT2C receptor subtypes.

It also displays a strong affinity as an antagonist to several [[dopamine|dopaminergic]] receptors, but shows only weak antagonism at the dopamine D2 receptor, which is commonly thought to modulate neuroleptic activity.

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==Legality==

*'''United States:''' Clozapine is not a controlled substance, but is a prescription-only medicine. Bloodwork for a condition called agranulocytosis is often done for safety before prescribing.

*'''United States:''' Clozapine is not a controlled substance, but is a prescription-only medicine. Bloodwork for a condition called agranulocytosis is often done for safety before prescribing and sometimes while on the medication.

*'''Australia:''' Clozapine is a schedule four substance, meaning it is a prescription-only medicine.

==See also==

* [[Responsible use]]

*[[Responsible use]]

* [[Antipsychotic]]

*[[Antipsychotic]]

*[[Delusions]]

*[[Quetiapine]]

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-{{decree|type=style|message=Neither the link format follows our usual format, nor does a summary or a verified substance box exist. Please help by contributing, so that this article can be published.}}
+{{decree|type=style|message=Neither the link format follows our usual format, nor does a summary or a verified substance box exist. Please help by contributing so that this article can be published.}}
 {{headerpanel|{{stub}} {{proofread}}}}
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 ==Pharmacology==
-Cloazapine is classified as and was the first atypical antipsychotic agent. It binds to several types of central nervous system receptors and displays a unique pharmacological profile. It is a [[serotonin]] antagonist, with strong binding to the 5-HT<sub>2A</sub> and 5-HT<sub>2C</sub> receptor subtypes.
+Clozapine is classified as and was the first atypical antipsychotic agent. It binds to several types of central nervous system receptors and displays a unique pharmacological profile. It is a [[serotonin]] antagonist, with strong binding to the 5-HT<sub>2A</sub> and 5-HT<sub>2C</sub> receptor subtypes.
 It also displays a strong affinity as an antagonist to several [[dopamine|dopaminergic]] receptors, but shows only weak antagonism at the dopamine D2 receptor, which is commonly thought to modulate neuroleptic activity.
@@ Line 66: / Line 66: @@
 ==Legality==
 {{LegalStub}}
-*'''United States:''' Clozapine is not a controlled substance, but is a prescription-only medicine. Bloodwork for a condition called agranulocytosis is often done for safety before prescribing.
+*'''United States:''' Clozapine is not a controlled substance, but is a prescription-only medicine. Bloodwork for a condition called agranulocytosis is often done for safety before prescribing and sometimes while on the medication.
 *'''Australia:''' Clozapine is a schedule four substance, meaning it is a prescription-only medicine.
 ==See also==
-* [[Responsible use]]
+*[[Responsible use]]
-* [[Antipsychotic]]
+*[[Antipsychotic]]
 *[[Delusions]]
 *[[Quetiapine]]