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Talk:4-CA: Difference between revisions
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{{SubstanceBox/4-CA}} | {{SubstanceBox/4-CA}} | ||
'''4-Chloroamphetamine''' (also known as '''4-CA''', '''4-CMP''', '''''para''-Chloroamphetamine''', '''PCA''' and '''P-CMP''') is a novel synthetic [[chemical class::amphetamine|substituted amphetamine]] that induces a mixture of [[psychoactive class::entactogen|entactogenic]] and [[psychoactive class::stimulant]] effects when [[Routes of administration|administered]]. | '''4-Chloroamphetamine''' (also known as '''4-CA''', '''4-CMP''', '''''para''-Chloroamphetamine''', '''PCA''' and '''P-CMP''') is a novel synthetic [[chemical class::amphetamine|substituted amphetamine]] that induces a mixture of [[psychoactive class::entactogen|entactogenic]] and [[psychoactive class::stimulant]] effects when [[Routes of administration|administered]]. | ||
4-CA is known for its severe [[Releasing_agent#Neurotoxicity|neurotoxicity]] and | 4-CA is known for its severe [[Releasing_agent#Neurotoxicity|neurotoxicity]] and was found to selectively destruct serotonergic neurons in animal study.<ref>{{cite journal |last1=Miller|first1=Krys J.|last2=Anderholm|first2=David C.|last3=Ames|first3=Matthew M.|date=1986|title=Metabolic activation of the serotonergic neurotoxin para-chloroamphetamine to chemically reactive intermediates by hepatic and brain microsomal preparations|journal=Biochemical Pharmacology|volume=35|issue=10|pages=1737-1742|doi=10.1016/0006-2952(86)90332-1|issn=0006-2952}}</ref> | ||
It is highly recommended to avoid the use of this substance and to use [[harm reduction]] practices if done anyway. | It is highly recommended to avoid the use of this substance and to use [[harm reduction]] practices if done anyway. | ||
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==See also== | ==See also== | ||
*[[Responsible use]] | *[[Responsible use]] | ||
*[[Releasing_agent#Neurotoxicity|Neurotoxicity]] | |||
*[[Research chemical]] | *[[Research chemical]] | ||
*[[4-FA]] | |||
*[[4-CMA]] | *[[4-CMA]] | ||