User:Stasconstantine/etrПсиходелики: Difference between revisions

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While the method of action behind psychedelics is not fully understood, serotonergic psychedelics are known to show affinities for various 5-HT receptors in different ways and levels and may be classified by their activity at different 5-HT subsites, such as 5-HT1A, 5-HT1B, 5-HT2A, etc. Many serotonergic psychedelics (such as the [[tryptamine|tryptamines]]) share very close chemical and structural similarities to serotonin itself which is thought to account for the range of affinities to 5-HT sites that it displays. It is almost unanimously agreed that serotonergic psychedelics produce their effects by acting as uniquely effective [[Agonist#Agonists|partial agonists]] at 5-HT2A receptor sites.<ref name="nicholspsy">Nichols, D. E. (2016). Psychedelics. ''Pharmacological Reviews'', 68(2), 264-355. https://doi.org/10.1124/pr.115.011478</ref>

==~~Subjective effects=~~=

==Эффекты=

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 While the method of action behind psychedelics is not fully understood, serotonergic psychedelics are known to show affinities for various 5-HT receptors in different ways and levels and may be classified by their activity at different 5-HT subsites, such as 5-HT<sub>1A</sub>, 5-HT<sub>1B</sub>, 5-HT<sub>2A</sub>, etc. Many serotonergic psychedelics (such as the [[tryptamine|tryptamines]]) share very close chemical and structural similarities to serotonin itself which is thought to account for the range of affinities to 5-HT sites that it displays. It is almost unanimously agreed that serotonergic psychedelics produce their effects by acting as uniquely effective [[Agonist#Agonists|partial agonists]] at 5-HT<sub>2A</sub> receptor sites.<ref name="nicholspsy">Nichols, D. E. (2016). Psychedelics. ''Pharmacological Reviews'', 68(2), 264-355. https://doi.org/10.1124/pr.115.011478</ref>
-==Subjective effects==
+==Эффекты=
 {{Preamble/SubjectiveEffects}}