Talk:Clozapine: Difference between revisions

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==Toxicity and harm potential==

Clozapine is associated with a rare but potentially fatal effect called agranulocytosis (dangerously low white blood cell count).<ref>Mebanga Ojong and Shari N. Allen (2013) Management and prevention of agranulocytosis in patients receiving clozapine. Mental Health Clinician: September 2013, Vol. 3, No. 3, pp. 139-143. https://doi.org/10.9740/mhc.n166825</ref> Therefore lower doses and self-monitoring for this condition are encouraged if taken outside of supervised medical context.

Clozapine is associated with a rare but potentially fatal effect called agranulocytosis (dangerously low white blood cell count).<ref>Mebanga Ojong and Shari N. Allen (2013) Management and prevention of agranulocytosis in patients receiving clozapine. Mental Health Clinician: September 2013, Vol. 3, No. 3, pp. 139-143. https://doi.org/10.9740/mhc.n166825</ref> Therefore, lower doses and self-monitoring for this condition are encouraged if taken outside of supervised medical context.

Clozapine can also cause NMS, or neuroleptic malignant syndrome. This reaction is rare, but serious and includes dysfunctions such as muscle rigidity, hyperthermia, paleness, psychomotor agitation, respiratory distress (tachypnea), among others.{{citation needed}}

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 ==Toxicity and harm potential==
-Clozapine is associated with a rare but potentially fatal effect called agranulocytosis (dangerously low white blood cell count).<ref>Mebanga Ojong and Shari N. Allen (2013) Management and prevention of agranulocytosis in patients receiving clozapine. Mental Health Clinician: September 2013, Vol. 3, No. 3, pp. 139-143. https://doi.org/10.9740/mhc.n166825</ref> Therefore lower doses and self-monitoring for this condition are encouraged if taken outside of supervised medical context.
+Clozapine is associated with a rare but potentially fatal effect called agranulocytosis (dangerously low white blood cell count).<ref>Mebanga Ojong and Shari N. Allen (2013) Management and prevention of agranulocytosis in patients receiving clozapine. Mental Health Clinician: September 2013, Vol. 3, No. 3, pp. 139-143. https://doi.org/10.9740/mhc.n166825</ref> Therefore, lower doses and self-monitoring for this condition are encouraged if taken outside of supervised medical context.
 Clozapine can also cause NMS, or neuroleptic malignant syndrome. This reaction is rare, but serious and includes dysfunctions such as muscle rigidity, hyperthermia, paleness, psychomotor agitation, respiratory distress (tachypnea), among others.{{citation needed}}