Sedative: Difference between revisions

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A '''sedative''' or '''tranquilizer''' (or '''tranquilliser'''~~, see [[American and British English spelling differences]])~~ is a substance that induces [[sedation]] by reducing [[irritability]]<ref name="urlJohns Hopkins Colon Cancer Center - Glossary S">{{cite web |url=http://www.hopkinscoloncancercenter.org/index.cfm?cID=194&CFID=1128737&CFTOKEN=20842936 |title=Johns Hopkins Colon Cancer Center - Glossary S |format= |work= |accessdate=}}</ref> or [[Psychomotor agitation|excitement]].<ref>{{DorlandsDict|seven/000095557|sedative}}</ref>

A '''sedative''' or '''tranquilizer''' or '''tranquilliser''' is a substance that induces [[Physical effects: Sedation|sedation]] by reducing [[irritability]]<ref name="urlJohns Hopkins Colon Cancer Center - Glossary S">{{cite web |url=http://www.hopkinscoloncancercenter.org/index.cfm?cID=194&CFID=1128737&CFTOKEN=20842936 |title=Johns Hopkins Colon Cancer Center - Glossary S |format= |work= |accessdate=}}</ref> or [[Psychomotor agitation|excitement]].<ref>{{DorlandsDict|seven/000095557|sedative}}</ref>

At higher doses it may result in slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes. Doses of sedatives such as [[benzodiazepines]], when used to induce [[sleep]], tend to be higher than amounts used to relieve anxiety, whereas only low doses are needed to provide a peaceful effect.<ref>{{cite journal |author=Montenegro M, Veiga H, Deslandes A, et al. |title=[Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study.] |journal=Arq Neuropsiquiatr |volume=63 |issue=2B |pages=410–5 |date=June 2005 |pmid=16059590 |doi=10.1590/S0004-282X2005000300009 |url=http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000300009&lng=en&nrm=iso&tlng=en }}</ref>

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-A '''sedative''' or '''tranquilizer''' (or '''tranquilliser''', see [[American and British English spelling differences]])  is a substance that induces [[sedation]] by reducing [[irritability]]<ref name="urlJohns Hopkins Colon Cancer Center - Glossary S">{{cite web |url=http://www.hopkinscoloncancercenter.org/index.cfm?cID=194&CFID=1128737&CFTOKEN=20842936 |title=Johns Hopkins Colon Cancer Center - Glossary S |format= |work= |accessdate=}}</ref> or [[Psychomotor agitation|excitement]].<ref>{{DorlandsDict|seven/000095557|sedative}}</ref>
+A '''sedative''' or '''tranquilizer''' or '''tranquilliser'''  is a substance that induces [[Physical effects: Sedation|sedation]] by reducing [[irritability]]<ref name="urlJohns Hopkins Colon Cancer Center - Glossary S">{{cite web |url=http://www.hopkinscoloncancercenter.org/index.cfm?cID=194&CFID=1128737&CFTOKEN=20842936 |title=Johns Hopkins Colon Cancer Center - Glossary S |format= |work= |accessdate=}}</ref> or [[Psychomotor agitation|excitement]].<ref>{{DorlandsDict|seven/000095557|sedative}}</ref>
 At higher doses it may result in slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes. Doses of sedatives such as [[benzodiazepines]], when used to induce [[sleep]], tend to be higher than amounts used to relieve anxiety, whereas only low doses are needed to provide a peaceful effect.<ref>{{cite journal |author=Montenegro M, Veiga H, Deslandes A, et al. |title=[Neuromodulatory effects of caffeine and bromazepam on visual event-related potential (P300): a comparative study.] |journal=Arq Neuropsiquiatr |volume=63 |issue=2B |pages=410–5 |date=June 2005 |pmid=16059590 |doi=10.1590/S0004-282X2005000300009  |url=http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2005000300009&lng=en&nrm=iso&tlng=en }}</ref>