Talk:Clozapine: Difference between revisions

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==Toxicity and harm potential==

Clozapine ~~can cause~~ agranulocytosis ~~as mentioned before~~, ~~and therefore~~ lower doses and self-monitoring for this condition are ~~ideal. Clozapine can be dispensed by prescription, and~~ if ~~you already have a prescription, you should know your blood test results~~ of ~~red, amber, or green. You should not accept clozapine from people or sources you do not trust, and this goes the same for any other drug~~. Clozapine can also cause NMS, or neuroleptic malignant syndrome. This reaction is rare, but serious and includes dysfunctions such as muscle rigidity, hyperthermia, paleness, psychomotor agitation, respiratory distress (tachypnea), ~~and more. Tripsitters should be used and, once again, low doses should be started with~~.

Clozapine is associated with a rare but potentially fatal effect called agranulocytosis (dangerously low white blood cell count).<ref>Mebanga Ojong and Shari N. Allen (2013) Management and prevention of agranulocytosis in patients receiving clozapine. Mental Health Clinician: September 2013, Vol. 3, No. 3, pp. 139-143. https://doi.org/10.9740/mhc.n166825</ref> Therefore lower doses and self-monitoring for this condition are encouraged if taken outside of supervised medical context.

Clozapine can also cause NMS, or neuroleptic malignant syndrome. This reaction is rare, but serious and includes dysfunctions such as muscle rigidity, hyperthermia, paleness, psychomotor agitation, respiratory distress (tachypnea), among others.{{citation needed}}

~~[[File:clozapine dispensing guidelines to prevent ah.PNG|400px]]~~

==Legality==

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 ==Toxicity and harm potential==
-Clozapine can cause agranulocytosis as mentioned before, and therefore lower doses and self-monitoring for this condition are ideal. Clozapine can be dispensed by prescription, and if you already have a prescription, you should know your blood test results of red, amber, or green. You should not accept clozapine from people or sources you do not trust, and this goes the same for any other drug. Clozapine can also cause NMS, or neuroleptic malignant syndrome. This reaction is rare, but serious and includes dysfunctions such as muscle rigidity, hyperthermia, paleness, psychomotor agitation, respiratory distress (tachypnea), and more. Tripsitters should be used and, once again, low doses should be started with.
+Clozapine is associated with a rare but potentially fatal effect called agranulocytosis (dangerously low white blood cell count).<ref>Mebanga Ojong and Shari N. Allen (2013) Management and prevention of agranulocytosis in patients receiving clozapine. Mental Health Clinician: September 2013, Vol. 3, No. 3, pp. 139-143. https://doi.org/10.9740/mhc.n166825</ref> Therefore lower doses and self-monitoring for this condition are encouraged if taken outside of supervised medical context.
+Clozapine can also cause NMS, or neuroleptic malignant syndrome. This reaction is rare, but serious and includes dysfunctions such as muscle rigidity, hyperthermia, paleness, psychomotor agitation, respiratory distress (tachypnea), among others.{{citation needed}}
-[[File:clozapine dispensing guidelines to prevent ah.PNG|400px]]
 ==Legality==
 {{LegalStub}}