5F-AKB48: Difference between revisions

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Unlike [[cannabis]], the chronic abuse of [[synthetic cannabinoids]] has been [[Synthetic_cannabinoid#Deaths|associated with multiple serious injuries deaths]] and [[Synthetic cannabinoid#Harm potential|more dangerous side effects and toxicity]] in general. Therefore, it is strongly discouraged to take this substance for extended periods of time or in excessive doses.

==Chemistry==

5F-AKB48, or N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, is a synthetic [[Chemical class::indazole cannabinoid]] as it contains a substituted indazole group. This indazole moeity is substituted at R1 with a fluoropentyl chain, a substitution shared with [[5F-PB-22]]. Additionally, the indazole is substituted at R3 with a carboxamide group. This carboxamide group is N-substituted at its terminal amine group with an adamantane group. This group consists of four fused cyclohexane rings in a unique structure called a diamondoid. 5F-AKB48 is an analog of [[STS-135]] in which the core indole structure is substituted with an indazole base.

5F-AKB48, or N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, is a synthetic [[Chemical class::indazole cannabinoid]] as it contains a substituted indazole group. This indazole moeity is substituted at R1 with a fluoropentyl chain, a substitution shared with [[5F-PB-22]]. Additionally, the indazole is substituted at R3 with a carboxamide group. This carboxamide group is N-substituted at its terminal amine group with an [[adamantane]] group. This group consists of four fused cyclohexane rings in a unique structure called a diamondoid. 5F-AKB48 is an analog of [[STS-135]] in which the core indole structure is substituted with an indazole base.

==Pharmacology==

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 Unlike [[cannabis]], the chronic abuse of [[synthetic cannabinoids]] has been [[Synthetic_cannabinoid#Deaths|associated with multiple serious injuries deaths]] and [[Synthetic cannabinoid#Harm potential|more dangerous side effects and toxicity]] in general. Therefore, it is strongly discouraged to take this substance for extended periods of time or in excessive doses.
 ==Chemistry==
-F-AKB48, or N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, is a synthetic [[Chemical class::indazole cannabinoid]] as it contains a substituted indazole group. This indazole moeity is substituted at R<sub>1</sub> with a fluoropentyl chain, a substitution shared with [[5F-PB-22]]. Additionally, the indazole is substituted at R<sub>3</sub> with a carboxamide group.  This carboxamide group is N-substituted at its terminal amine group with an adamantane group. This group consists of four fused cyclohexane rings in a unique structure called a diamondoid. 5F-AKB48 is an analog of [[STS-135]] in which the core indole structure is substituted with an indazole base.
+F-AKB48, or N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, is a synthetic [[Chemical class::indazole cannabinoid]] as it contains a substituted indazole group. This indazole moeity is substituted at R<sub>1</sub> with a fluoropentyl chain, a substitution shared with [[5F-PB-22]]. Additionally, the indazole is substituted at R<sub>3</sub> with a carboxamide group.  This carboxamide group is N-substituted at its terminal amine group with an [[adamantane]] group. This group consists of four fused cyclohexane rings in a unique structure called a diamondoid. 5F-AKB48 is an analog of [[STS-135]] in which the core indole structure is substituted with an indazole base.
 ==Pharmacology==