Talk:Hydroxyzine: Difference between revisions
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{{SubstanceBox/Hydroxyzine}} | {{SubstanceBox/Hydroxyzine}} | ||
'''Hydroxyzine''' is a [[psychoactive class:: antihistamine]] substance of the [[chemical class::diphenylmethylpiperazine]] class. | '''Hydroxyzine''' is a [[psychoactive class::antihistamine]] substance of the [[chemical class::diphenylmethylpiperazine]] class. | ||
It is in the piperazine family of chemicals.<ref>"Hydroxyzine Hydrochloride Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 21 Nov 2018.</ref> It's main mechanism of action is as a potent and selective histamine H1 receptor antagonist.<ref>Szepietowski J, Weisshaar E (2016). Itin P, Jemec GB (eds.). Itch - Management in Clinical Practice. Current Problems in Dermatology. 50. Karger Medical and Scientific Publishers. pp. 1–80. ISBN 9783318058895.</ref><ref>Hosák L, Hrdlička M, et al. (2017). Psychiatry and Pedopsychiatry. Charles University in Prague, Karolinum Press. p. 364. ISBN 9788024633787.</ref> | It is in the [[psychoactive class::piperazine]] family of chemicals.<ref>"Hydroxyzine Hydrochloride Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 21 Nov 2018.</ref> It's main mechanism of action is as a potent and selective histamine H1 receptor antagonist.<ref>Szepietowski J, Weisshaar E (2016). Itin P, Jemec GB (eds.). Itch - Management in Clinical Practice. Current Problems in Dermatology. 50. Karger Medical and Scientific Publishers. pp. 1–80. ISBN 9783318058895.</ref><ref>Hosák L, Hrdlička M, et al. (2017). Psychiatry and Pedopsychiatry. Charles University in Prague, Karolinum Press. p. 364. ISBN 9788024633787.</ref> | ||
It was first made by Union Chimique Belge in 1956 and was approved for sale by Pfizer in the United States later that year.<ref></ref>Shorter E (2009). Before Prozac: the troubled history of mood disorders in psychiatry. Oxford [Oxfordshire]: Oxford University Press. ISBN 9780195368741.<ref>Shorter E (2009). Before Prozac: the troubled history of mood disorders in psychiatry. Oxford [Oxfordshire]: Oxford University Press. ISBN 9780195368741.</ref> | It was first made by Union Chimique Belge in 1956 and was approved for sale by Pfizer in the United States later that year.<ref></ref>Shorter E (2009). Before Prozac: the troubled history of mood disorders in psychiatry. Oxford [Oxfordshire]: Oxford University Press. ISBN 9780195368741.<ref>Shorter E (2009). Before Prozac: the troubled history of mood disorders in psychiatry. Oxford [Oxfordshire]: Oxford University Press. ISBN 9780195368741.</ref> |