1P-ETH-LAD: Difference between revisions

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1P-ETH-LAD, or 1-propionyl-6-ethyl-6-nor-lysergic acid diethyamide, is a semi-synthethic alkaloid of the [[lysergamide]] famiy. 1P-ETH-LAD is a structural analogue of lysergic acid, with an N,N-diethylamide functional group bound to RN of the chemical structure. This core polycyclic structure is an indole derivative, and has [[tryptamine]] and [[phenethylamine]] groups embedded within it.

1P-ETH-LAD's structure contains a bicyclic hexahydroindole fused to a bicyclic quinoline group (nor-lysergic acid). 1P-ETH-LAD does not contain a methyl group substituted at R6 of its nor-lysgeric acid skeleton, this is represented by the nor- prefix. Instead, 1P-ETH-LAD is substituted at R6 with an ethyl group. At carbon 8 of the quinoline a N,N-diethyl carboxamide is bound.

1P-ETH-LAD's structure contains a bicyclic hexahydroindole fused to a bicyclic quinoline group (nor-lysergic acid). 1P-ETH-LAD does not contain a methyl group substituted at R6 of its nor-lysgeric acid skeleton, this is represented by the nor- prefix. Instead, 1P-ETH-LAD is substituted at R6 with an ethyl group and at R1 with a propionyl group. At carbon 8 of the quinoline a N,N-diethyl carboxamide is bound.

1P-ETH-LAD is a chiral compound with two stereocenters at R5 and R8. AL-LAD, also called (+)-D-A1P-ETH-LAD, has an absolute configuration of (5''R'', 8''R''). The three other stereoisomers of 1P-ETH-LAD do not have psychoactive properties.{{citation needed}}

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 P-ETH-LAD, or 1-propionyl-6-ethyl-6-nor-lysergic acid diethyamide, is a semi-synthethic alkaloid of the [[lysergamide]] famiy. 1P-ETH-LAD is a structural analogue of lysergic acid, with an N,N-diethylamide functional group bound to R<sub>N</sub> of the chemical structure. This core polycyclic structure is an indole derivative, and has [[tryptamine]] and [[phenethylamine]] groups embedded within it.
-P-ETH-LAD's structure contains a bicyclic hexahydroindole fused to a bicyclic quinoline group (nor-lysergic acid). 1P-ETH-LAD does not contain a methyl group substituted at R<sub>6</sub> of its nor-lysgeric acid skeleton, this is represented by the nor- prefix. Instead, 1P-ETH-LAD is substituted at R<sub>6</sub> with an ethyl group. At carbon 8 of the quinoline a N,N-diethyl carboxamide is bound.
+P-ETH-LAD's structure contains a bicyclic hexahydroindole fused to a bicyclic quinoline group (nor-lysergic acid). 1P-ETH-LAD does not contain a methyl group substituted at R<sub>6</sub> of its nor-lysgeric acid skeleton, this is represented by the nor- prefix. Instead, 1P-ETH-LAD is substituted at R<sub>6</sub> with an ethyl group and at R<sub>1</sub> with a propionyl group. At carbon 8 of the quinoline a N,N-diethyl carboxamide is bound.
 P-ETH-LAD is a chiral compound with two stereocenters at R<sub>5</sub> and R<sub>8</sub>. AL-LAD, also called (+)-D-A1P-ETH-LAD, has an absolute configuration of (5''R'', 8''R''). The three other stereoisomers of 1P-ETH-LAD do not have psychoactive properties.{{citation needed}}