Seizure: Difference between revisions

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An '''epileptic seizure''' (colloquially a '''fit''') is a brief episode of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain.<ref>Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/15816939</ref> The outward effect can vary from uncontrolled jerking movement (tonic-clonic seizure) to as subtle as a momentary loss of awareness (absence seizure). The disease of the brain characterized by an enduring predisposition to generate epileptic seizures is called epilepsy,<ref>Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/15816939</ref><ref>ILAE official report: a practical clinical definition of epilepsy (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/24730690</ref> but seizures can also occur in people who do not have epilepsy.  
An '''epileptic seizure''' (colloquially a '''fit''') is a brief episode of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain.<ref>Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/15816939</ref> The outward effect can vary from uncontrolled jerking movement (tonic-clonic seizure) to as subtle as a momentary loss of awareness (absence seizure). The disease of the brain characterized by an enduring predisposition to generate epileptic seizures is called epilepsy,<ref>Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/15816939</ref><ref>ILAE official report: a practical clinical definition of epilepsy (PubMed.gov / NCBI) | http://www.ncbi.nlm.nih.gov/pubmed/24730690</ref> but seizures can also occur in people who do not have epilepsy.  


This can occur due to a variety of causes and is common during withdrawals from prolonged chronic [[benzodiazepine]] usage or during an overdose on certain substances such as [[stimulant]]s, [[Synthetic cannabinoid|synthetic cannabinoids]] and the [[25x-NBOMe]] series of [[psychedelic]]s.</onlyinclude>
This can occur due to a variety of causes and is common during withdrawals from prolonged chronic [[benzodiazepine]] usage or during an overdose on certain substances such as [[stimulant]]s, [[Synthetic cannabinoid|synthetic cannabinoids]] and the [[25x-NBOMe]] series of [[psychedelic]]s. It has also been noted that opioid overdoses can cause seizures. This is believed to happen because many opioids, despite being [[depressants]], have significant intrinsic activity at the sigma receptors. </onlyinclude>
 
Seizures, depending on the cause, are generally treated with [[seizure suppression |anticonvulsant]] drugs such as [[diazepam]] and [[pregabalin]].
===See also===
===See also===
*[[Responsible use]]
*[[Responsible use]]