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Talk:Ginkgo Biloba: Difference between revisions
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Ginkgo biloba, commonly known as ginkgo or gingko, also known as the maidenhair tree, is a species of tree native to China used as medicine. The tree was cultivated early in human history and remains commonly planted. | Ginkgo biloba, commonly known as ginkgo or gingko, also known as the maidenhair tree, is a species of tree native to China used as medicine. The tree was cultivated early in human history and remains commonly planted. | ||
Usually taken orally, as an | Usually taken orally, as an extract in a capsule or pressed pill, or infusing the leaves in hot water to drink it as a tea. | ||
Adults have used between 120 and 240 milligrams a day in divided doses. It appears to take 4 to 6 weeks before improvements are noticed, also it have an immediate effect. | |||
Ginkgo leaf extract is commonly used as a dietary supplement, but there is no scientific evidence that it supports human health or is effective against any disease. | Ginkgo leaf extract is commonly used as a dietary supplement, but there is no scientific evidence that it supports human health or is effective against any disease. | ||
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==History and culture== | ==History and culture== | ||
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==Chemistry== | ==Chemistry== | ||
{{chemistry}} | {{chemistry}} | ||
The active compounds in ginkgo are Bilobalide, Ginkgoic acid, Ginkgolide-A, Ginkgotoxin (a neurotoxin that in large amounts can cause seizures. Is found in ginkgo seeds and, to a lesser extent, ginkgo leaves), Isorhamnetin, Amentoflavone, Ginkgetin, others... | |||
==Pharmacology== | ==Pharmacology== | ||
{{pharmacology}} | {{pharmacology}} | ||
Ginkgo biloba supplements have been shown to increase dopamine levels in animal and test-tube studies. | |||
Both ginkgolides and bilobalide inhibit GABA(A) receptors, with bilobalide demonstrating a more potent effect. | |||
Ginkgo biloba Extract (GbE) Restores Serotonin and Leptin Receptor Levels and Plays an Antioxidative Role in the Hippocampus of Ovariectomized Rats. | |||
==Subjective effects== | ==Subjective effects== | ||
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{{toxicity}} | {{toxicity}} | ||
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance. | It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance. | ||
If you are older, have a bleeding disorder or are pregnant, don't take ginkgo. The supplement might increase your risk of bleeding. If you're planning to have surgery, stop taking ginkgo two weeks beforehand. | |||
In an open trial ginkgo biloba, an extract derived from the leaf of the Chinese ginkgo tree and noted for its cerebral enhancing effects, was found to be 84% effective in treating antidepressant-induced sexual dysfunction predominately caused by selective serotonin reuptake inhibitors | |||
Several studies show that ginkgo has a positive effect on memory and thinking in people with Alzheimer disease or vascular dementia. | |||
===Lethal dosage=== | ===Lethal dosage=== | ||
===Tolerance and addiction potential=== | ===Tolerance and addiction potential=== | ||