Research chemicals: Difference between revisions

>Oskykins
No edit summary
>Oskykins
No edit summary
Line 8: Line 8:
In terms of risk factors, Erowid states that "mislabeling, misidentification, issues of purity, adulteration, and misrepresentation (substitution) are unfortunately a common problem with research chemicals."<ref name="erowid">Experimental & Research Chemicals (Synthetic Drugs, Novel Psychoactive Substances, New Psychoactive Substances, NPS, Replacement Psychoactives) (Erowid) | https://www.erowid.org/psychoactives/research_chems/</ref> It is recommended that one avoid branded products or blends if the active psychoactive compounds are not listed on the labelling.<ref name="tripsit">Research Chemicals (Tripsit) | https://wiki.tripsit.me/wiki/Research_Chemicals</ref> Combining research chemicals also presents an unknown risk due to the lack of research.
In terms of risk factors, Erowid states that "mislabeling, misidentification, issues of purity, adulteration, and misrepresentation (substitution) are unfortunately a common problem with research chemicals."<ref name="erowid">Experimental & Research Chemicals (Synthetic Drugs, Novel Psychoactive Substances, New Psychoactive Substances, NPS, Replacement Psychoactives) (Erowid) | https://www.erowid.org/psychoactives/research_chems/</ref> It is recommended that one avoid branded products or blends if the active psychoactive compounds are not listed on the labelling.<ref name="tripsit">Research Chemicals (Tripsit) | https://wiki.tripsit.me/wiki/Research_Chemicals</ref> Combining research chemicals also presents an unknown risk due to the lack of research.


Caution should be used when dosing because not much is known about the dose range and lethal doses. Research chemicals which have caused death at high doses include [[25I-NBOMe]]<ref name="one">25I-NBOMe (2C-I-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2ci_nbome/2ci_nbome_death.shtml</ref>, [[25B-NBOMe]]<ref name="three">Other or Unknown NBOMe Compound Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/nbome/nbome_death.shtml</ref>, [[25C-NBOMe]]<ref name="two">25C-NBOMe (2C-C-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2cc_nbome/2cc_nbome_death.shtml</ref>, [[AMT]]<ref name="amt">AMT (Alphamethyltryptamine, IT-290) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/amt/amt_death.shtml</ref><ref name="amt2">Boland DM, Andollo W, Hime GW, Hearn WL. “Fatality due to acute alpha-methyltryptamine intoxication”. J Anal Toxicol. 2005 Jul-Aug;29(5):394-7. | https://www.erowid.org/references/refs_view.php?ID=6603</ref>,  
Caution should be used when dosing because not much is known about the dose range, lethal dosage, and harmful side effects. Some research chemicals have produced unexpected adverse side effects due to the lack of screening for off-target effects prior to marketing; both [[bromo-dragonfly]] and [[mephedrone]] seem to be capable of producing pronounced [[vasoconstriction]] under some circumstances, which has resulted in several deaths<ref>A fatal poisoning involving Bromo-Dragonfly. | https://www.ncbi.nlm.nih.gov/pubmed/19091499</ref>. Substituted phenethylamines such as the [[2C-x|2C family]] and [[substituted amphetamines]] such as the [[DOx]] family have also caused a limited number of deaths. Other research chemicals which have been reported to cause death at high doses include [[25I-NBOMe]]<ref name="one">25I-NBOMe (2C-I-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2ci_nbome/2ci_nbome_death.shtml</ref>, [[25B-NBOMe]]<ref name="three">Other or Unknown NBOMe Compound Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/nbome/nbome_death.shtml</ref>, [[25C-NBOMe]]<ref name="two">25C-NBOMe (2C-C-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2cc_nbome/2cc_nbome_death.shtml</ref>, [[AMT]]<ref name="amt">AMT (Alphamethyltryptamine, IT-290) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/amt/amt_death.shtml</ref><ref name="amt2">Boland DM, Andollo W, Hime GW, Hearn WL. “Fatality due to acute alpha-methyltryptamine intoxication”. J Anal Toxicol. 2005 Jul-Aug;29(5):394-7. | https://www.erowid.org/references/refs_view.php?ID=6603</ref>,  
 


Dosing
Dosing