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Buspirone: Difference between revisions

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{{Substance Breakdown}}
 
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{{SummarySheet}}
'''Buspirone''' (trade name '''Buspar''' among others) is an [[Anxiety suppression|anxiolytic]] substance of the [[azapirone]] class. It is primarily used to treat [[Anxiety|anxiety disorders]], particularly generalized anxiety disorder (GAD.)<ref>[https://www.drugs.com/monograph/buspirone.html "Buspirone Hydrochloride Monograph for Professionals".] ''[https://drugs.com Drugs.com]''</ref> It is a [[serotonin]] 5-HT<sub>1A</sub> [[receptor]] [[Agonist|partial agonist]], increasing action at serotonin receptors in the brain.<ref>Loane C, Politis M (June 2012). "Buspirone: what is it all about?". ''Brain Research''. '''1461''': 111–118. https://doi.org/10.1016%2Fj.brainres.2012.04.032</ref>
 
It is often prescribed as a safer alternative to [[benzodiazepines]] for anxiety as it does not activate [[GABA|GABA receptors]] and does not possess any addiction liability.<ref>Wilson TK, Tripp J (January 2018). [https://www.ncbi.nlm.nih.gov/books/NBK531477/ "Buspirone".]</ref> At therapeutic doses, it has no immediate anxiolytic effects and hence has a delayed [[Onset|onset of action]]; its full clinical effectiveness may require 2–4 weeks to manifest itself.{{SubstanceBox/Buspirone}}
 
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==History and culture==
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==Chemistry==
{{chemistry}}
==Pharmacology==
{{pharmacology}}
 
==Subjective effects==
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===Experience reports===
{{Experience reports|erowid_experience_substance_label=Pharms - Buspirone}}
 
==Toxicity and harm potential==
{{toxicity}}
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
===Lethal dosage===
===Tolerance and addiction potential===
===Dangerous interactions===
{{DangerousInteractions}}
{{DangerousInteractions/Intro}}
 
==Legal status==
{{LegalStub}}
 
==See also==
 
*[[Responsible use]]
 
==External links==
 
*[https://en.wikipedia.org/wiki/Buspirone Buspirone (Wikipedia)]
 
==Literature==
 
*APA formatted reference
 
Please see the [[citation formatting guide]] if you need assistance properly formatting citations.
 
==References==
<references />
 
[[Category:Psychoactive substance]]
[[Category:Proofread]]
[[Category:Approval]]
Retrieved from "https://psy.st/wiki/Buspirone"