This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Depression reduction: Difference between revisions
>Graham m →Euthymia: updating links to reflect nomenclature changes |
>Graham m Undo revision 166769 by Graham Just having a bit of fun |
||
| (6 intermediate revisions by 2 users not shown) | |||
| Line 2: | Line 2: | ||
'''Depression reduction''' is the experience of minimizing the symptoms associated with [[depression]] and low mood states. It is distinct from effects such as [[cognitive euphoria]], as it does not simply elevate the user's mood but instead results in a sense of stable emotional well-being. | '''Depression reduction''' is the experience of minimizing the symptoms associated with [[depression]] and low mood states. It is distinct from effects such as [[cognitive euphoria]], as it does not simply elevate the user's mood but instead results in a sense of stable emotional well-being. | ||
Depression reduction most commonly occurs with adequate nutritional intake.<ref name="BenderHagan2017">{{cite journal|last1=Bender|first1=Ansley|last2=Hagan|first2=Kelsey E.|last3=Kingston|first3=Neal|title=The association of folate and depression: A meta-analysis|journal=Journal of Psychiatric Research|volume=95|year=2017|pages=9–18|issn=00223956|doi=10.1016/j.jpsychires.2017.07.019}}</ref><ref name="Spedding2014">{{cite journal|last1=Spedding|first1=Simon|title=Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws|journal=Nutrients|volume=6|issue=4|year=2014|pages=1501–1518|issn=2072-6643|doi=10.3390/nu6041501}}</ref><ref name="SubletteEllis2011">{{cite journal|last1=Sublette|first1=M. Elizabeth|last2=Ellis|first2=Steven P.|last3=Geant|first3=Amy L.|last4=Mann|first4=J. John|title=Meta-Analysis of the Effects of Eicosapentaenoic Acid (EPA) in Clinical Trials in Depression|journal=The Journal of Clinical Psychiatry|volume=72|issue=12|year=2011|pages=1577–1584|issn=0160-6689|doi=10.4088/JCP.10m06634}}</ref><ref name="HuangWang2016">{{cite journal|last1=Huang|first1=Ruixue|last2=Wang|first2=Ke|last3=Hu|first3=Jianan|title=Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials|journal=Nutrients|volume=8|issue=8|year=2016|pages=483|issn=2072-6643|doi=10.3390/nu8080483}}</ref><ref name="NgKoh2017">{{cite journal|last1=Ng|first1=Qin Xiang|last2=Koh|first2=Shawn Shao Hong|last3=Chan|first3=Hwei Wuen|last4=Ho|first4=Collin Yih Xian|title=Clinical Use of Curcumin in Depression: A Meta-Analysis|journal=Journal of the American Medical Directors Association|volume=18|issue=6|year=2017|pages=503–508|issn=15258610|doi=10.1016/j.jamda.2016.12.071}}</ref> Severe depression is effectively reduced with conventional antidepressants; although in mild to moderate depression, SSRI's and tricyclic antidepressants appear (on average) to be either only minimally helpful or completely ineffective.<ref name="FournierDeRubeis2010">{{cite journal|last1=Fournier|first1=Jay C.|last2=DeRubeis|first2=Robert J.|last3=Hollon|first3=Steven D.|last4=Dimidjian|first4=Sona|last5=Amsterdam|first5=Jay D.|last6=Shelton|first6=Richard C.|last7=Fawcett|first7=Jan|title=Antidepressant Drug Effects and Depression Severity|journal=JAMA|volume=303|issue=1|year=2010|pages=47|issn=0098-7484|doi=10.1001/jama.2009.1943}}</ref> However, depression reduction can also occur under the influence of | Depression reduction most commonly occurs with adequate nutritional intake.<ref name="BenderHagan2017">{{cite journal|last1=Bender|first1=Ansley|last2=Hagan|first2=Kelsey E.|last3=Kingston|first3=Neal|title=The association of folate and depression: A meta-analysis|journal=Journal of Psychiatric Research|volume=95|year=2017|pages=9–18|issn=00223956|doi=10.1016/j.jpsychires.2017.07.019}}</ref><ref name="Spedding2014">{{cite journal|last1=Spedding|first1=Simon|title=Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws|journal=Nutrients|volume=6|issue=4|year=2014|pages=1501–1518|issn=2072-6643|doi=10.3390/nu6041501}}</ref><ref name="SubletteEllis2011">{{cite journal|last1=Sublette|first1=M. Elizabeth|last2=Ellis|first2=Steven P.|last3=Geant|first3=Amy L.|last4=Mann|first4=J. John|title=Meta-Analysis of the Effects of Eicosapentaenoic Acid (EPA) in Clinical Trials in Depression|journal=The Journal of Clinical Psychiatry|volume=72|issue=12|year=2011|pages=1577–1584|issn=0160-6689|doi=10.4088/JCP.10m06634}}</ref><ref name="HuangWang2016">{{cite journal|last1=Huang|first1=Ruixue|last2=Wang|first2=Ke|last3=Hu|first3=Jianan|title=Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials|journal=Nutrients|volume=8|issue=8|year=2016|pages=483|issn=2072-6643|doi=10.3390/nu8080483}}</ref><ref name="NgKoh2017">{{cite journal|last1=Ng|first1=Qin Xiang|last2=Koh|first2=Shawn Shao Hong|last3=Chan|first3=Hwei Wuen|last4=Ho|first4=Collin Yih Xian|title=Clinical Use of Curcumin in Depression: A Meta-Analysis|journal=Journal of the American Medical Directors Association|volume=18|issue=6|year=2017|pages=503–508|issn=15258610|doi=10.1016/j.jamda.2016.12.071}}</ref> Severe depression is effectively reduced with conventional antidepressants; although in mild to moderate depression, SSRI's and tricyclic antidepressants appear (on average) to be either only minimally helpful or completely ineffective.<ref name="FournierDeRubeis2010">{{cite journal|last1=Fournier|first1=Jay C.|last2=DeRubeis|first2=Robert J.|last3=Hollon|first3=Steven D.|last4=Dimidjian|first4=Sona|last5=Amsterdam|first5=Jay D.|last6=Shelton|first6=Richard C.|last7=Fawcett|first7=Jan|title=Antidepressant Drug Effects and Depression Severity|journal=JAMA|volume=303|issue=1|year=2010|pages=47|issn=0098-7484|doi=10.1001/jama.2009.1943}}</ref> However, depression reduction can also occur under the influence of testosterone replacement therapies<ref name="ZarroufArtz2009">{{cite journal|last1=Zarrouf|first1=Fahd Aziz|last2=Artz|first2=Steven|last3=Griffith|first3=James|last4=Sirbu|first4=Cristian|last5=Kommor|first5=Martin|title=Testosterone and Depression|journal=Journal of Psychiatric Practice|volume=15|issue=4|year=2009|pages=289–305|issn=1538-1145|doi=10.1097/01.pra.0000358315.88931.fc}}</ref><ref>{{cite journal | vauthors=((Walther, A.)), ((Breidenstein, J.)), ((Miller, R.)) | journal=JAMA Psychiatry | title=Association of Testosterone Treatment With Alleviation of Depressive Symptoms in Men: A Systematic Review and Meta-analysis | volume=76 | issue=1 | pages=31 | date=1 January 2019 | url=http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/jamapsychiatry.2018.2734 | issn=2168-622X | doi=10.1001/jamapsychiatry.2018.2734 | access-date=29 May 2022}}</ref> (increased estrogen is associated with an increase in depression in young men regardless of BMI)<ref>{{cite journal | vauthors=((Stanikova, D.)), ((Luck, T.)), ((Bae, Y. J.)), ((Thiery, J.)), ((Ceglarek, U.)), ((Engel, C.)), ((Enzenbach, C.)), ((Wirkner, K.)), ((Stanik, J.)), ((Kratzsch, J.)), ((Riedel-Heller, S. G.)) | journal=Psychoneuroendocrinology | title=Increased estrogen level can be associated with depression in males | volume=87 | pages=196–203 | date= January 2018 | url=https://linkinghub.elsevier.com/retrieve/pii/S0306453017304195 | issn=03064530 | doi=10.1016/j.psyneuen.2017.10.025 | access-date=15 April 2025}}</ref> and modafinil.<ref name="RockRoiser2013">{{cite journal|last1=Rock|first1=P. L.|last2=Roiser|first2=J. P.|last3=Riedel|first3=W. J.|last4=Blackwell|first4=A. D.|title=Cognitive impairment in depression: a systematic review and meta-analysis|journal=Psychological Medicine|volume=44|issue=10|year=2013|pages=2029–2040|issn=0033-2917|doi=10.1017/S0033291713002535}}</ref> | ||
===Euthymia=== | ===Euthymia=== | ||