Talk:2F-NENDCK: Difference between revisions

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{{headerpanel|{{Approval}}}}

~~{{SummarySheet}}~~

~~[[File:2F-NENDCK_structure.png|400px]]~~

==History and culture==

{{2F-NENDCK (short for 2-fluoro-N–ethylnordeschloroketamine, also known as CanKET, 2’-fluoro-2-oxo-PCE or 2-FXE) is a novel synthetic dissociative drug was first identified in Canberra, Australia (2022) at Cantest, a legal anonymous substance testing site, Novel synthetic substances have been typically put under the category of "designer drug"

2F-NENDCK (short for 2-fluoro-N–ethylnordeschloroketamine, also known as CanKET, 2’-fluoro-2-oxo-PCE or 2-FXE) is a novel synthetic dissociative drug was first identified in Canberra, Australia (2022) at Cantest, a legal anonymous substance testing site, Novel synthetic substances have been typically put under the category of "designer drug"

CanKet (Canberra Ketamine) gained its name for its Ketamine like properties and effects.

Canket has since been discovered being manufactured in laboratory's in mainland China and Taiwan.

The original CanKet samples and many since have reportably came from sales at festivals and bush parties in the NSW mountain ranges specifically around the Brindabella mountain range.

At CanTEST, 2F-NENDCK has been found numerous times in samples that were expected to be ketamine. According to CanTEST’s final evaluation, only 57% of the 81 samples expected to be ketamine actually contained ketamine as of April 2023. The remaining 43% of the 81 samples contained other dissociative drugs, including 2F-NENDCK, 2F-DCK, and tiletamine (a veterinary dissociative anaesthetic), as well as other psychoactive and non-psychoactive compounds. According to DrugsData.org, a drug checking service in the US that analyses samples sent by mail, numerous samples sold as ketamine, FXE, 2F, MXE, 2F-DCK, and even heroin, fentanyl and ibogaine, actually contained 2F-NENDCK.}}

At CanTEST, 2F-NENDCK has been found numerous times in samples that were expected to be ketamine. According to CanTEST’s final evaluation, only 57% of the 81 samples expected to be ketamine actually contained ketamine as of April 2023. The remaining 43% of the 81 samples contained other dissociative drugs, including 2F-NENDCK, 2F-DCK, and tiletamine (a veterinary dissociative anaesthetic), as well as other psychoactive and non-psychoactive compounds. According to DrugsData.org, a drug checking service in the US that analyses samples sent by mail, numerous samples sold as ketamine, FXE, 2F, MXE, 2F-DCK, and even heroin, fentanyl and ibogaine, actually contained 2F-NENDCK.

==Chemistry==

2F-NENDCK belongs to the [https://psychonautwiki.org/wiki/Arylcyclohexylamines arylcyclohexylamines] category of substances, this category includes ketamine, PCP and other substances alike.

2F-NENDCK is remarkably simmilair to ketamine structually, it only differs in 2 points. [https://www.cahma.org.au/wp-content/uploads/2023/08/image.png ~~see photo~~] [https://chemapps.stolaf.edu/jmol/jmol.php?model=CCNC1%28CCCCC1%3DO%29C2%3DCC%3DCC%3DC2F interactive 2F-NENDCK model]

2F-NENDCK is remarkably simmilair to ketamine structually, it only differs in 2 points, 2F-NENDCK is also similar to [https://psychonautwiki.org/wiki/Fluorexetamine FXE] as it only differs in one point. [https://www.cahma.org.au/wp-content/uploads/2023/08/image.png ket/canket differences] [https://www.cahma.org.au/wp-content/uploads/2024/01/image.png canket/FXE differences] [https://chemapps.stolaf.edu/jmol/jmol.php?model=CCNC1%28CCCCC1%3DO%29C2%3DCC%3DCC%3DC2F interactive 2F-NENDCK model]

==Pharmacology==

there has been no official pharmacology or lab testing done on 2F-NENDCK

there has been no official pharmacology or lab testing done on 2F-NENDCK.

==Subjective effects==

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===Physical Effects===

~~You may select physical~~ effects to ~~add below [[Subjective effect index#Physical effects|here]]~~.

along with the list of these effects, 2F-NENDCK has also been known to produce a next day hangover, typically leaving the user feeling quite "cloudy" and "foggy".

*[https://psychonautwiki.org/wiki/Dizziness dizziness] 2F-NENDCK can have dizzy/spinning head effects in moderate dosage. some users report difficulty walking.

*[https://psychonautwiki.org/wiki/Sedation sedation] 2F-NENDCK has little sedation in lighter doses, but can induce [https://psychonautwiki.org/wiki/Ketamine ketamine] like sedation in higher doses. 2F-NENDCK's sedation is closer related to heavy [https://psychonautwiki.org/wiki/Cannabis Cannabis] couch lock.

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*[https://psychonautwiki.org/wiki/Acuity_suppression acuity suppression]

*[https://psychonautwiki.org/wiki/Frame_rate_suppression frame rate suppression] not to the same extent as [https://psychonautwiki.org/wiki/Ketamine ketamine], but can still be present in higher doses

*[https://psychonautwiki.org/wiki/Perspective_distortion]

*[https://psychonautwiki.org/wiki/Perspective_distortion perspective distortion]

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It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance, also learn about [https://psychonautwiki.org/wiki/Responsible_drug_use responsible drug use] before using this and any psychoactive substance.

===Lethal dosage===

there has been no documented lethal ~~dose or any~~ dose for ~~that matter.~~

there has been no documented lethal dose for 2F-NENDCK.

~~The following is a rough guide for dosing ketamine as a reference (not~~ 2F-NENDCK):

~~LOW DOSE – 20-50 mg~~

~~MEDIUM DOSE – 50-125 mg~~

~~STRONG DOSE – 125-175 mg~~

~~HEAVY DOSE, POSSIBLE ANAESTHESIA – 175+ mg~~

===Tolerance and addiction potential===

===Dangerous interactions===

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==Legal status==

~~at the moment I can not find any hard evidence on its legality~~ in Australia ~~although as it belongs to the~~ [https://~~psychonautwiki~~.~~org~~/~~wiki~~/~~Arylcyclohexylamines arylcyclohexylamines~~] ~~category of drugs, i can only assume it isn't federally legal and i would worn anyone on possessing, distributing and purchasing this substance~~.

as of April 2024 2F-NENDCK is unscheduled in Australia. see [https://www.odc.gov.au/controlled-substances/list controlled substance list] for up to date information.

==See also==

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(List along order below)

* [https://en.wikipedia.org/wiki/SUBSTANCE SUBSTANCE (Wikipedia)]

* SUBSTANCE (Erowid Vault)

* SUBSTANCE ([''PiHKAL'' or ''TiHKAL''] / Isomer Design)

==Literature==

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==References==

* [https://en.wikipedia.org/wiki/2F-NENDCK]

* [https://en.wikipedia.org/wiki/2F-NENDCK wikipedia]

*[https://www.cahma.org.au/article/safer-using-canket/]

* [https://www.cahma.org.au/article/safer-using-canket/ cahma]

* [https://www.odc.gov.au/controlled-substances/list AUS controlled substance list]

* [https://www.vice.com/en/article/5d3jp5/scientists-discover-imitation-ketamine-on-the-market VICE]

* [https://ndarc.med.unsw.edu.au/sites/default/files/ndarc/resources/NPS_bulletin_2023.pdf NPS bulletin]

[[Category:Psychoactive substance]][[Category:Proofread]][[Category:Approval]]

@@ Line 3: / Line 3: @@
 {{headerpanel|{{Approval}}}}
-{{SummarySheet}}
 {{SubstanceBox/2F-NENDCK}}
-[[File:2F-NENDCK_structure.png|400px]]
 ==History and culture==
-{{2F-NENDCK (short for 2-fluoro-N–ethylnordeschloroketamine, also known as CanKET, 2’-fluoro-2-oxo-PCE or 2-FXE) is a novel synthetic dissociative drug was first identified in Canberra, Australia (2022) at Cantest, a legal anonymous substance testing site, Novel synthetic substances have been typically put under the category of "designer drug"
+F-NENDCK (short for 2-fluoro-N–ethylnordeschloroketamine, also known as CanKET, 2’-fluoro-2-oxo-PCE or 2-FXE) is a novel synthetic dissociative drug was first identified in Canberra, Australia (2022) at Cantest, a legal anonymous substance testing site, Novel synthetic substances have been typically put under the category of "designer drug"
 CanKet (Canberra Ketamine) gained its name for its Ketamine like properties and effects.
 Canket has since been discovered being manufactured in laboratory's in mainland China and Taiwan.
 The original CanKet samples and many since have reportably came from sales at festivals and bush parties in the NSW mountain ranges specifically around the Brindabella mountain range.
-At CanTEST, 2F-NENDCK has been found numerous times in samples that were expected to be ketamine. According to CanTEST’s final evaluation, only 57% of the 81 samples expected to be ketamine actually contained ketamine as of April 2023. The remaining 43% of the 81 samples contained other dissociative drugs, including 2F-NENDCK, 2F-DCK, and tiletamine (a veterinary dissociative anaesthetic), as well as other psychoactive and non-psychoactive compounds. According to DrugsData.org, a drug checking service in the US that analyses samples sent by mail, numerous samples sold as ketamine, FXE, 2F, MXE, 2F-DCK, and even heroin, fentanyl and ibogaine, actually contained 2F-NENDCK.}}
+At CanTEST, 2F-NENDCK has been found numerous times in samples that were expected to be ketamine. According to CanTEST’s final evaluation, only 57% of the 81 samples expected to be ketamine actually contained ketamine as of April 2023. The remaining 43% of the 81 samples contained other dissociative drugs, including 2F-NENDCK, 2F-DCK, and tiletamine (a veterinary dissociative anaesthetic), as well as other psychoactive and non-psychoactive compounds. According to DrugsData.org, a drug checking service in the US that analyses samples sent by mail, numerous samples sold as ketamine, FXE, 2F, MXE, 2F-DCK, and even heroin, fentanyl and ibogaine, actually contained 2F-NENDCK.
 ==Chemistry==
 F-NENDCK belongs to the [https://psychonautwiki.org/wiki/Arylcyclohexylamines arylcyclohexylamines] category of substances, this category includes ketamine, PCP and other substances alike.
-F-NENDCK is remarkably simmilair to ketamine structually, it only differs in 2 points. [https://www.cahma.org.au/wp-content/uploads/2023/08/image.png see photo] [https://chemapps.stolaf.edu/jmol/jmol.php?model=CCNC1%28CCCCC1%3DO%29C2%3DCC%3DCC%3DC2F interactive 2F-NENDCK model]
+F-NENDCK is remarkably simmilair to ketamine structually, it only differs in 2 points, 2F-NENDCK is also similar to [https://psychonautwiki.org/wiki/Fluorexetamine FXE] as it only differs in one point.  [https://www.cahma.org.au/wp-content/uploads/2023/08/image.png ket/canket differences] [https://www.cahma.org.au/wp-content/uploads/2024/01/image.png canket/FXE differences] [https://chemapps.stolaf.edu/jmol/jmol.php?model=CCNC1%28CCCCC1%3DO%29C2%3DCC%3DCC%3DC2F interactive 2F-NENDCK model]
 ==Pharmacology==
 {{pharmacology}}
-there has been no official pharmacology or lab testing done on 2F-NENDCK
+there has been no official pharmacology or lab testing done on 2F-NENDCK.
 ==Subjective effects==
@@ Line 27: / Line 27: @@
 ===Physical Effects===
-You may select physical effects to add below [[Subjective effect index#Physical effects|here]].
+along with the list of these effects, 2F-NENDCK has also been known to produce a next day hangover, typically leaving the user feeling quite "cloudy" and "foggy".
 *[https://psychonautwiki.org/wiki/Dizziness dizziness] 2F-NENDCK can have dizzy/spinning head effects in moderate dosage. some users report difficulty walking.
 *[https://psychonautwiki.org/wiki/Sedation sedation] 2F-NENDCK has little sedation in lighter doses, but can induce [https://psychonautwiki.org/wiki/Ketamine ketamine] like sedation in higher doses. 2F-NENDCK's sedation is closer related to heavy [https://psychonautwiki.org/wiki/Cannabis Cannabis] couch lock.
@@ Line 53: / Line 52: @@
 *[https://psychonautwiki.org/wiki/Acuity_suppression acuity suppression]
 *[https://psychonautwiki.org/wiki/Frame_rate_suppression frame rate suppression] not to the same extent as [https://psychonautwiki.org/wiki/Ketamine ketamine], but can still be present in higher doses
-*[https://psychonautwiki.org/wiki/Perspective_distortion]
+*[https://psychonautwiki.org/wiki/Perspective_distortion perspective distortion]
@@ Line 93: / Line 92: @@
 It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance, also learn about [https://psychonautwiki.org/wiki/Responsible_drug_use responsible drug use] before using this and any psychoactive substance.
 ===Lethal dosage===
-there has been no documented lethal dose or any dose for that matter.
+there has been no documented lethal dose for 2F-NENDCK.
-The following is a rough guide for dosing ketamine as a reference (not 2F-NENDCK):
-LOW DOSE – 20-50 mg
-MEDIUM DOSE – 50-125 mg
-STRONG DOSE – 125-175 mg
-HEAVY DOSE, POSSIBLE ANAESTHESIA – 175+ mg
 ===Tolerance and addiction potential===
 ===Dangerous interactions===
@@ Line 120: / Line 111: @@
 ==Legal status==
 {{LegalStub}}
-at the moment I can not find any hard evidence on its legality in Australia although as it belongs to the [https://psychonautwiki.org/wiki/Arylcyclohexylamines arylcyclohexylamines] category of drugs, i can only assume it isn't federally legal and i would worn anyone on possessing, distributing and purchasing this substance.
+as of April 2024 2F-NENDCK is unscheduled in Australia. see [https://www.odc.gov.au/controlled-substances/list controlled substance list] for up to date information.
 ==See also==
@@ Line 128: / Line 119: @@
 (List along order below)
 * [https://en.wikipedia.org/wiki/SUBSTANCE SUBSTANCE (Wikipedia)]
-* SUBSTANCE (Erowid Vault)
-* SUBSTANCE ([''PiHKAL'' or ''TiHKAL''] / Isomer Design)
 ==Literature==
@@ Line 138: / Line 127: @@
 ==References==
 <references />
-* [https://en.wikipedia.org/wiki/2F-NENDCK]
+* [https://en.wikipedia.org/wiki/2F-NENDCK wikipedia]
-*[https://www.cahma.org.au/article/safer-using-canket/]
+* [https://www.cahma.org.au/article/safer-using-canket/ cahma]
+* [https://www.odc.gov.au/controlled-substances/list AUS controlled substance list]
+* [https://www.vice.com/en/article/5d3jp5/scientists-discover-imitation-ketamine-on-the-market VICE]
+* [https://ndarc.med.unsw.edu.au/sites/default/files/ndarc/resources/NPS_bulletin_2023.pdf NPS bulletin]
 [[Category:Psychoactive substance]][[Category:Proofread]][[Category:Approval]]