This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Ibotenic acid: Difference between revisions
>AlexanderTheGreat added to the effects and chemistry areas |
>Tracer Added Categories |
||
| (11 intermediate revisions by 3 users not shown) | |||
| Line 1: | Line 1: | ||
{{headerpanel|{{stub}}}} | {{headerpanel|{{stub}}}} | ||
{{SubstanceBox/Ibotenic acid}} | |||
'''Ibotenic acid''' or '''(''S'')-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid''' (also referred to as '''ibotenate''') is a psychoactive substance which occurs naturally in ''[[Amanita muscaria]]'' and related species of mushrooms. It is an analogue of the neurotransmitter [[glutamate]], and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist.{{citation needed}} | '''Ibotenic acid''' or '''(''S'')-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid''' (also referred to as '''ibotenate''') is a psychoactive substance which occurs naturally in ''[[Amanita muscaria]]'' and related species of mushrooms. It is an analogue of the neurotransmitter [[glutamate]], and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist.{{citation needed}} | ||
Ibotenic acid | Ibotenic acid is a powerful neurotoxin, and has been employed as a "brain-lesioning agent" through cranial injections in scientific research conducted in rats.{{citation needed}} The same properties have not been studied in humans, however it could very well be a human neurotoxin as well. | ||
==Chemistry== | ==Chemistry== | ||
{{chemistry}} | {{chemistry}} | ||
==Pharmacology== | ==Pharmacology== | ||
| Line 24: | Line 15: | ||
{{effectStub}}The most common symptoms include nausea, vomiting, and drowsiness. However, after the first hour symptoms begin to include confusion, euphoria, visual and auditory distortions, sensations of floating, and retrograde amnesia. | {{effectStub}}The most common symptoms include nausea, vomiting, and drowsiness. However, after the first hour symptoms begin to include confusion, euphoria, visual and auditory distortions, sensations of floating, and retrograde amnesia. | ||
Symptoms are slightly different for children, typically beginning after 30–180 minutes. Dominant symptoms in children include ataxia, obtundation, and lethargy. Seizures are occasionally reported, however, more commonly with children.<ref>https://en.wikipedia.org/ | Symptoms are slightly different for children, typically beginning after 30–180 minutes. Dominant symptoms in children include ataxia, obtundation, and lethargy. Seizures are occasionally reported, however, more commonly with children.<ref>{{Citation | year=2022 | title=Ibotenic acid | url=https://en.wikipedia.org/w/index.php?title=Ibotenic_acid&oldid=1095441575}}</ref> | ||
[[Category:Amino acid]] | |||
[[Category:3-Hydroxyisoxazole]] | |||
[[Category:Hallucinogen]] | |||
==References== | ==References== | ||
{{references}} | {{references}} | ||
<references /> | <references /> | ||