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Ibotenic acid: Difference between revisions
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'''Ibotenic acid''' or '''(''S'')-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid''' (also referred to as '''ibotenate''') is a psychoactive substance which occurs naturally in ''[[Amanita muscaria]]'' and related species of mushrooms. It is an analogue of the neurotransmitter [[glutamate]], and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist.{{citation needed}} | '''Ibotenic acid''' or '''(''S'')-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid''' (also referred to as '''ibotenate''') is a psychoactive substance which occurs naturally in ''[[Amanita muscaria]]'' and related species of mushrooms. It is an analogue of the neurotransmitter [[glutamate]], and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist.{{citation needed}} | ||
Ibotenic acid | Ibotenic acid is a powerful neurotoxin, and has been employed as a "brain-lesioning agent" through cranial injections in scientific research conducted in rats.{{citation needed}} The same properties have not been studied in humans, however it could very well be a human neurotoxin as well. | ||
==Chemistry== | ==Chemistry== | ||
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==Pharmacology== | ==Pharmacology== | ||
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Symptoms are slightly different for children, typically beginning after 30–180 minutes. Dominant symptoms in children include ataxia, obtundation, and lethargy. Seizures are occasionally reported, however, more commonly with children.<ref>{{Citation | year=2022 | title=Ibotenic acid | url=https://en.wikipedia.org/w/index.php?title=Ibotenic_acid&oldid=1095441575}}</ref> | Symptoms are slightly different for children, typically beginning after 30–180 minutes. Dominant symptoms in children include ataxia, obtundation, and lethargy. Seizures are occasionally reported, however, more commonly with children.<ref>{{Citation | year=2022 | title=Ibotenic acid | url=https://en.wikipedia.org/w/index.php?title=Ibotenic_acid&oldid=1095441575}}</ref> | ||
[[Category:Amino acid]] | |||
[[Category:3-Hydroxyisoxazole]] | |||
[[Category:Hallucinogen]] | |||
==References== | ==References== | ||
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