Talk:Aripiprazole: Difference between revisions

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==Chemistry==

Aripiprazole is a synthetic substance of the quinolinone class and is structurally distinct from other atypical antipsychotics. Its molecular formula is ~~C_{~~23~~}H_{~~27~~}Cl_{~~2~~}N_{~~3~~}O_{~~2}, and it has a unique mechanism of action as a dopamine-serotonin system stabilizer.

Aripiprazole is a synthetic substance of the quinolinone class and is structurally distinct from other atypical antipsychotics. Its molecular formula is C23H27Cl2N3O2, and it has a unique mechanism of action as a dopamine-serotonin system stabilizer.

==Pharmacology==

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}}

{{effects/cognitive|

|{{effects/cognitive|

Cognitive effects of Aripiprazole can include:

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* '''[[Effect::Insomnia]]''' - Difficulty falling or staying asleep in some individuals.

* '''[[Effect::Memory suppression|Short-term memory suppression]]''' - In rare cases, may affect short-term memory.

}}

~~{{effects/auditory|~~

~~Auditory effects are typically therapeutic in nature, reducing symptoms in those with auditory hallucinations due to mental health conditions:~~

* '''[[Effect::Decreased auditory hallucinations]]''' - Often effective in reducing or eliminating auditory hallucinations in schizophrenia or other psychotic disorders.

}}

~~{{effects/visual|~~

~~The visual effects of Aripiprazole are comparable to that of certain aspects [[deliriants]] and [[dissociatives]].~~

*'''[[Effect::Acuity suppression]]'''

*'''[[Effect::Double vision]]''' - [[Double vision]] is a common side effect, especially at higher doses and can cause long-term problems with vision depending on the duration of use.

*'''[[Effect::Shadow people]]''' - This effect is rarely seen with therapeutic use.

}}

==Experience reports==

There are a limited number of experience reports for Aripiprazole given its medical usage, but some can be found in the [[experience index]] and on external platforms like Erowid.

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==External links==

*[https://en.wikipedia.org/wiki/Aripiprazole Aripiprazole (Wikipedia)]

*[https://www.~~erowid~~.~~org/pharms~~/aripiprazole/ Aripiprazole (~~Erowid Vault~~)]

*[https://isomerdesign.com/pihkal/explore/9511 Aripiprazole (Isomer Design)]

*[https://go.drugbank.com/drugs/DB01238 Aripiprazole (DrugBank)]

*[https://www.drugs.com/aripiprazole.html Aripiprazole (Drugs.com)]

==References==

The 2016 [[NICE]] guidance for treating psychosis and schizophrenia in children and young people recommended aripiprazole as a second line treatment after [[risperidone]] for people between 15 and 17 who are having an acute exacerbation or recurrence of psychosis or schizophrenia.<ref>{{cite web |title=Psychosis and schizophrenia in children and young people: recognition and management {{!}} Guidance and guidelines {{!}} NICE |url=https://www.nice.org.uk/guidance/cg155/chapter/Recommendations |publisher=NICE |date=October 2016}}</ref> A 2014 NICE review of the depot formulation of the drug found that it might have a role in treatment as an alternative to other depot formulations of second generation antipsychotics for people who have trouble taking medication as directed or who prefer it.<ref>{{cite web |title=Schizophrenia: aripiprazole prolonged-release suspension for injection {{!}} Guidance and guidelines {{!}} NICE |url=https://www.nice.org.uk/advice/esnm39/chapter/Key-points-from-the-evidence |publisher=NICE |date=24 July 2013}}</ref>

[[Category:Psychoactive substance]][[Category:Proofread]][[Category:Approval]]

@@ Line 9: / Line 9: @@
 ==Chemistry==
-Aripiprazole is a synthetic substance of the quinolinone class and is structurally distinct from other atypical antipsychotics. Its molecular formula is C_{23}H_{27}Cl_{2}N_{3}O_{2}, and it has a unique mechanism of action as a dopamine-serotonin system stabilizer.
+Aripiprazole is a synthetic substance of the quinolinone class and is structurally distinct from other atypical antipsychotics. Its molecular formula is C<sub>23</sub>H<sub>27</sub>Cl<sub>2</sub>N<sub>3</sub>O<sub>2</sub>, and it has a unique mechanism of action as a dopamine-serotonin system stabilizer.
 ==Pharmacology==
@@ Line 33: / Line 33: @@
 }}
-{{effects/cognitive|
+|{{effects/cognitive|
 Cognitive effects of Aripiprazole can include:
@@ Line 45: / Line 45: @@
 * '''[[Effect::Insomnia]]''' - Difficulty falling or staying asleep in some individuals.
 * '''[[Effect::Memory suppression|Short-term memory suppression]]''' - In rare cases, may affect short-term memory.
 }}
-{{effects/auditory|
-Auditory effects are typically therapeutic in nature, reducing symptoms in those with auditory hallucinations due to mental health conditions:
-* '''[[Effect::Decreased auditory hallucinations]]''' - Often effective in reducing or eliminating auditory hallucinations in schizophrenia or other psychotic disorders.
 }}
-{{effects/visual|
-The visual effects of Aripiprazole are comparable to that of certain aspects [[deliriants]] and [[dissociatives]].
-*'''[[Effect::Acuity suppression]]'''
-*'''[[Effect::Double vision]]''' - [[Double vision]] is a common side effect, especially at higher doses and can cause long-term problems with vision depending on the duration of use.
-*'''[[Effect::Shadow people]]''' - This effect is rarely seen with therapeutic use.
-}}
 ==Experience reports==
 There are a limited number of experience reports for Aripiprazole given its medical usage, but some can be found in the [[experience index]] and on external platforms like Erowid.
@@ Line 86: / Line 73: @@
 ==External links==
 *[https://en.wikipedia.org/wiki/Aripiprazole Aripiprazole (Wikipedia)]
-*[https://www.erowid.org/pharms/aripiprazole/ Aripiprazole (Erowid Vault)]
+*[https://isomerdesign.com/pihkal/explore/9511 Aripiprazole (Isomer Design)]
+*[https://go.drugbank.com/drugs/DB01238 Aripiprazole (DrugBank)]
+*[https://www.drugs.com/aripiprazole.html Aripiprazole (Drugs.com)]
 ==References==
 <references />
-The 2016 [[NICE]] guidance for treating psychosis and schizophrenia in children and young people recommended aripiprazole as a second line treatment after [[risperidone]] for people between 15 and 17 who are having an acute exacerbation or recurrence of psychosis or schizophrenia.<ref>{{cite web |title=Psychosis and schizophrenia in children and young people: recognition and management {{!}} Guidance and guidelines {{!}} NICE |url=https://www.nice.org.uk/guidance/cg155/chapter/Recommendations |publisher=NICE |date=October 2016}}</ref> A 2014 NICE review of the depot formulation of the drug found that it might have a role in treatment as an alternative to other depot formulations of second generation antipsychotics for people who have trouble taking medication as directed or who prefer it.<ref>{{cite web |title=Schizophrenia: aripiprazole prolonged-release suspension for injection {{!}} Guidance and guidelines {{!}} NICE |url=https://www.nice.org.uk/advice/esnm39/chapter/Key-points-from-the-evidence |publisher=NICE |date=24 July 2013}}</ref>
 [[Category:Psychoactive substance]][[Category:Proofread]][[Category:Approval]]